7XB0

Crystal structure of Omicron BA.2 RBD complexed with hACE2

Summary for 7XB0

• Entry DOI: 10.2210/pdb7xb0/pdb
• Descriptor: Angiotensin-converting enzyme 2, Spike protein S1, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (6 entities in total)
• Functional Keywords: sars-cov-2, omicron, rbd, hace2, complex structure, viral protein, hydrolase-viral protein complex, hydrolase/viral protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 2
• Total formula weight: 93242.83

Authors

Li, L.,Liao, H.,Meng, Y.,Li, W. (deposition date: 2022-03-19, release date: 2022-07-06, Last modification date: 2023-11-29)

• Primary citation: Li, L.,Liao, H.,Meng, Y.,Li, W.,Han, P.,Liu, K.,Wang, Q.,Li, D.,Zhang, Y.,Wang, L.,Fan, Z.,Zhang, Y.,Wang, Q.,Zhao, X.,Sun, Y.,Huang, N.,Qi, J.,Gao, G.F.; Structural basis of human ACE2 higher binding affinity to currently circulating Omicron SARS-CoV-2 sub-variants BA.2 and BA.1.1.; Cell, 185:2952-2960.e10, 2022; PubMed: 35809570; DOI: 10.1016/j.cell.2022.06.023

Experimental method

X-RAY DIFFRACTION (2.9 Å)