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19861
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Q: When the data are updated?-
Recent 3DEM papers
-Cryo-EM structure of P-glycoprotein bound to triple elacridar inhibitor molecules.
Biochem Biophys Res Commun, Vol. 709, Page 149855, Year 2024
Norie Hamaguchi-Suzuki / Naruhiko Adachi / Toshio Moriya / Satoshi Yasuda / Masato Kawasaki / Kano Suzuki / Satoshi Ogasawara / Naohiko Anzai / Toshiya Senda / Takeshi Murata
Methods: EM (single particle)
38986
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38987
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-The pan-RAF-MEK non degrading molecular glue NST-628 is a potent and brain penetrant inhibitor of the RAS-MAPK pathway with activity across diverse RAS- and RAF-driven cancers.
Cancer Discov, Year 2024Meagan B Ryan / Bradley Quade / Natasha Schenk / Zhong Fang / Marshall Zingg / Steven E Cohen / Brooke M Swalm / Chun Li / Aysegul Ozen / Chaoyang Ye ...Meagan B Ryan / Bradley Quade / Natasha Schenk / Zhong Fang / Marshall Zingg / Steven E Cohen / Brooke M Swalm / Chun Li / Aysegul Ozen / Chaoyang Ye / Maria Stella Ritorto / Xin Huang / Arvin C Dar / Yongxin Han / Klaus P Hoeflich / Michael Hale / Margit Hagel
Methods: EM (single particle) / X-ray diffraction
43931
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43932
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+Removal of type IV pili by a small RNA virus.
+Molecular insights into capsular polysaccharide secretion.
+Mechanical activation opens a lipid-lined pore in OSCA ion channels.
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-Feb 9, 2022. New format data for meta-information of EMDB entries
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-Oct 5, 2021. Nobel Prize for mechanically activated and temperature-gated ion channels
Nobel Prize for mechanically activated and temperature-gated ion channels
- The Nobel Prize in Physiology or Medicine 2021 was awarded jointly to David Julius and Ardem Patapoutian "for their discoveries of receptors for temperature and touch."
- EM Navigator can help to find cryo-EM structure data by both pioneers.
External links:The Nobel Prize in Physiology or Medicine 2021 - NobelPrize.org / Structure data by Ardem Patapoutian / Structure data by David Julius
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+Mar 5, 2020. Novel coronavirus structure data
+Jul 5, 2019. Downlodablable text data
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