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Showing 1 - 50 of 74 items for (author: brown & ms)

EMDB-69219: 
TamA complex with TamB DUF490 in lipid nanodisc
Method: single particle / : Adamson LSR, Doyle MT, Grosas AB

EMDB-69220: 
TamA complex with TamB DUF490 in detergent micelles.
Method: single particle / : Adamson LSR, Doyle MT, Grosas AB

PDB-23sp: 
TamA complex with TamB DUF490 in lipid nanodisc
Method: single particle / : Adamson LSR, Doyle MT, Grosas AB

PDB-23sq: 
TamA complex with TamB DUF490 in detergent micelles.
Method: single particle / : Adamson LSR, Doyle MT, Grosas AB

EMDB-70721: 
TMPRSS2 (S441A) bound to the HCoV-NL63 S2'region genetically fused to the HCoV-HKU1 RBD
Method: single particle / : McCallum M, Seattle Structural Genomics Center for Infectious Disease (SSGCID), Veesler D

EMDB-70722: 
TMPRSS2 S441A in complex with the H1H7 Fab and anti-kappa light chain nanobody
Method: single particle / : McCallum M, Seattle Structural Genomics Center for Infectious Disease (SSGCID), Veesler D

EMDB-73656: 
SARS-CoV-2 spike trimer in the early fusion intermediate conformation bound to the VN01H1 Fab (Fab local refinement)
Method: single particle / : Park YJ, Seattle Structural Genomics Center for Infectious Disease (SSGCID), Veesler D

EMDB-73657: 
SARS-CoV-2 spike trimer in the early fusion intermediate conformation bound to the VN01H1 Fab (S2 local refinement)
Method: single particle / : Park YJ, Seattle Structural Genomics Center for Infectious Disease (SSGCID), Veesler D

EMDB-73786: 
HCoV-NL63 S2' peptide bound to TMPRSS2 S441A (complexed with the H1H7 Fab and an anti-kappa-nanobody)
Method: single particle / : McCallum M, Seattle Structural Genomics Center for Infectious Disease (SSGCID), Veesler D

EMDB-73787: 
SARS-CoV-2 S2 trimer stabilized in the early fusion intermediate conformation by circular permutation and clamping by gp41 (E-FICs-v1)
Method: single particle / : McCallum M, Seattle Structural Genomics Center for Infectious Disease (SSGCID), Veesler D

EMDB-75233: 
SARS-CoV-2 spike trimer in the early fusion intermediate conformation bound to the VN01H1 Fab (global refinement)
Method: single particle / : Park YJ, Seattle Structural Genomics Center for Infectious Disease (SSGCID), Veesler D

EMDB-75694: 
SARS-CoV-2 spike S2 trimer stabilized in the early fusion intermediate conformation (E-FICs-v3) bound to the VN01H1 Fab (Fab local refinement)
Method: single particle / : McCallum M, Seattle Structural Genomics Center for Infectious Disease (SSGCID), Veesler D

EMDB-75695: 
SARS-CoV-2 spike S2 trimer stabilized in the early fusion intermediate conformation (E-FICs-v3) bound to the VN01H1 Fab (S2 local refinement)
Method: single particle / : McCallum M, Seattle Structural Genomics Center for Infectious Disease (SSGCID), Veesler D

EMDB-75705: 
SARS-CoV-2 spike S2 trimer stabilized in the early fusion intermediate conformation (E-FICs-v3) bound to C77G12 (Fab local refinement)
Method: single particle / : McCallum M, Seattle Structural Genomics Center for Infectious Disease (SSGCID), Veesler D

EMDB-75721: 
SARS-CoV-2 spike S2 trimer stabilized in the early fusion intermediate conformation (E-FICs-v3) bound to the VN01H1 Fab
Method: single particle / : McCallum M, Seattle Structural Genomics Center for Infectious Disease (SSGCID), Veesler D

EMDB-75722: 
SARS-CoV-2 spike S2 trimer stabilized in the early fusion intermediate conformation (E-FICs-v3) bound to C77G12 (global refinement)
Method: single particle / : McCallum M, Seattle Structural Genomics Center for Infectious Disease (SSGCID), Veesler D

EMDB-75697: 
SARS-CoV-2 spike S2 trimer stabilized in the early fusion intermediate conformation (E-FICs-v3) bound to C77G12 (S2 local refinement)
Method: single particle / : McCallum M, Seattle Structural Genomics Center for Infectious Disease (SSGCID), Veesler D

EMDB-45969: 
Local refinement of the SARS-CoV-2 BA.2.86 RBD in complex with TRI2-2 minibinder
Method: single particle / : Lee J, Seattle Structural Genomics Center for Infectious Disease (SSGCID), Veesler D

EMDB-45971: 
Local refinement of the SARS-CoV-2 BA.2.86 NTD
Method: single particle / : Lee J, Seattle Structural Genomics Center for Infectious Disease (SSGCID), Veesler D

EMDB-45972: 
SARS-CoV-2 BA.2.86 Spike trimer in complex with TRI2-2 minibinder
Method: single particle / : Lee J, Veesler D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)

EMDB-46960: 
Designed miniproteins potently inhibit and protect against MERS-CoV. MERS-CoV S in complex with miniprotein cb3_GGGSGGGS_SB175, linker 7 (Local refinement of two RBDs and 2 miniproteins)
Method: single particle / : Tortorici MA, Veesler D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)

PDB-9dkk: 
Designed miniproteins potently inhibit and protect against MERS-CoV. MERS-CoV S in complex with miniprotein cb3_GGGSGGGS_SB175, linker 7 (Local refinement of two RBDs and 2 miniproteins)
Method: single particle / : Tortorici MA, Seattle Structural Genomics Center for Infectious Disease (SSGCID), Veesler D

EMDB-46947: 
Designed miniproteins potently inhibit and protect against MERS_CoV (Global refinement of MERS_CoV_S RBD in complex with miniprotein cb3_GSG_SB175, linker 1)
Method: single particle / : Tortorici MA, Veesler D

EMDB-46952: 
Designed miniproteins potently inhibit and protect against MERS_CoV. MERS_CoV S in complex with cb3_GSG_SB175, linker 1. Global refinement, three RBDs engaged.
Method: single particle / : Tortorici MA, Veesler D

EMDB-46955: 
Designed miniproteins potently inhibit and protect against MERS_CoV. MERS_CoV S in complex with cb3_GGGSGGGS_SB175, linker 7. Global refinement.
Method: single particle / : Tortorici MA, Veesler D

EMDB-46957: 
Designed miniproteins potently inhibit and protect against MERS_CoV. MERS-CoV S in complex with cb3_GGGSGGGS_SB175B175, linker 7(Global refinement after focused classification)
Method: single particle / : Tortorici MA, Veesler D

EMDB-53347: 
Structure of the 50S ribosomal subunit from the antibiotic-producing bacterium Streptomyces fradiae
Method: single particle / : Ekemezie CL, Melnikov SV

PDB-9qt5: 
Structure of the 50S ribosomal subunit from the antibiotic-producing bacterium Streptomyces fradiae
Method: single particle / : Ekemezie CL, Melnikov SV

EMDB-45448: 
Double-stacked pore and prepore-like complex (C1 symmetry)
Method: single particle / : Johnstone BA, Christie MP, Morton CJ, Brown HG, Hanssen E, Parker MW

EMDB-45449: 
Double-stacked pore and prepore-like complex (C30 symmetry)
Method: single particle / : Johnstone BA, Christie MP, Morton CJ, Brown HG, Hanssen E, Parker MW

EMDB-45450: 
EaCDCL pore complex (C1 symmetry)
Method: single particle / : Johnstone BA, Christie MP, Morton CJ, Brown HG, Hanssen E, Parker MW

EMDB-45451: 
Cryo-EM structure of the EaCDCL pore
Method: single particle / : Johnstone BA, Christie MP, Morton CM, Brown HG, Hanssen E, Parker MW

EMDB-45452: 
Prepore-like EaCDCL short oligomer (C1 symmetry)
Method: single particle / : Johnstone BA, Christie MP, Morton CJ, Brown HG, Hanssen E, Parker MW

EMDB-45453: 
Cryo-EM structure of the prepore-like EaCDCL short oligomer
Method: single particle / : Johnstone BA, Christie MP, Morton CM, Brown HG, Hanssen E, Parker MW

EMDB-45454: 
EaCDCL pore complex, non-stacked control (C1)
Method: single particle / : Johnstone BA, Christie MP, Morton CJ, Brown HG, Hanssen E, Parker MW

EMDB-45455: 
EaCDCL pore complex, non-stacked control (C30 symmetry)
Method: single particle / : Johnstone BA, Christie MP, Morton CJ, Brown HG, Hanssen E, Parker MW

PDB-9ccp: 
Cryo-EM structure of the EaCDCL pore
Method: single particle / : Johnstone BA, Christie MP, Morton CM, Brown HG, Hanssen E, Parker MW

PDB-9ccq: 
Cryo-EM structure of the prepore-like EaCDCL short oligomer
Method: single particle / : Johnstone BA, Christie MP, Morton CM, Brown HG, Hanssen E, Parker MW

EMDB-44103: 
Structure of the Porcine deltacoronavirus (PDCoV) receptor-binding domain bound to the PD33 antibody Fab fragment and the Kappa light chain nanobody
Method: single particle / : Park YJ, Seattle Structural Genomics Center for Infectious Disease (SSGCID), Veesler D

EMDB-46804: 
PDCoV S trimer bound by three copies of PD41 Fab
Method: single particle / : Asarnow D, Rexhepaj M, Seattle Structural Genomics Center for Infectious Disease (SSGCID), Veesler D

EMDB-46805: 
PDCoV S RBD bound to PD41 Fab (local refinement)
Method: single particle / : Asarnow D, Rexhepaj M, Seattle Structural Genomics Center for Infectious Disease (SSGCID), Veesler D

EMDB-46806: 
PDCoV S SD2018/300 Apo (Class I)
Method: single particle / : Asarnow D, Rexhepaj M, Seattle Structural Genomics Center for Infectious Disease (SSGCID), Veesler D, Center for Structural Genomics of Infectious Diseases (CSGID)

EMDB-46814: 
PDCoV S SD2018/300 with one PD41 Fab bound (Class II)
Method: single particle / : Asarnow D, Rexhepaj M, Seattle Structural Genomics Center for Infectious Disease (SSGCID), Veesler D, Center for Structural Genomics of Infectious Diseases (CSGID)

EMDB-46815: 
PDCoV S SD2018/300 with one PD41 Fab bound (Class III)
Method: single particle / : Asarnow D, Rexhepaj M, Seattle Structural Genomics Center for Infectious Disease (SSGCID), Veesler D, Center for Structural Genomics of Infectious Diseases (CSGID)

EMDB-46816: 
PDCoV S SD2018/300 with two PD41 Fabs bound (Class IV)
Method: single particle / : Asarnow D, Rexhepaj M, Seattle Structural Genomics Center for Infectious Disease (SSGCID), Veesler D, Center for Structural Genomics of Infectious Diseases (CSGID)

EMDB-43813: 
VIR-7229 Fab fragment bound the SARS-CoV-2 BA.2.86 spike trimer (local refinement of the BA 2.86 RBD/VIR-7229 VHVL)
Method: single particle / : Park YJ, Tortorici MA, Seattle Structural Genomics Center for Infectious Disease (SSGCID), Veesler D

EMDB-43842: 
VIR-7229 Fab fragment bound the BA.2.86 spike trimer (global refinement)
Method: single particle / : Tortorici MA, Park YJ, Veelser D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)

EMDB-40480: 
TUBB4B and TUBA1A Heterodimer from Human Respiratory Doublet Microtubules
Method: single particle / : Anderson JR, Gui M, Brown A

PDB-8sh7: 
TUBB4B and TUBA1A Heterodimer from Human Respiratory Doublet Microtubules
Method: single particle / : Anderson JR, Gui M, Brown A

EMDB-17539: 
Cryo-EM structure of dimeric UBR5
Method: single particle / : Aguirre JD, Kater L, Kempf G, Cavadini S, Thoma NH
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