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Showing 1 - 50 of 16,799 items for (author: hu & t)

EMDB-42676:
5-HT2AR bound to Lisuride in complex with a mini-Gq protein and an active-state stabilizing single-chain variable fragment (scFv16) obtained by cryo-electron microscopy (cryoEM)
Method: single particle / : Barros-Alvarez X, Kim K, Panova O, Roth BL, Skiniotis G

EMDB-42999:
5HT2AR-miniGq heterotrimer in complex with a novel agonist obtained from large scale docking
Method: single particle / : Gumpper RH, Wang L, Kapolka N, Skiniotis G, Roth BL

PDB-8uwl:
5-HT2AR bound to Lisuride in complex with a mini-Gq protein and an active-state stabilizing single-chain variable fragment (scFv16) obtained by cryo-electron microscopy (cryoEM)
Method: single particle / : Barros-Alvarez X, Kim K, Panova O, Roth BL, Skiniotis G

PDB-8v6u:
5HT2AR-miniGq heterotrimer in complex with a novel agonist obtained from large scale docking
Method: single particle / : Gumpper RH, Wang L, Kapolka N, Skiniotis G, Roth BL

EMDB-36989:
Full agonist-bound mu-type opioid receptor-G protein complex
Method: single particle / : Uchikubo-Kamo T, Shirouzu M, Hisano T, Imai S, Kaneko S, Shimada I

EMDB-36990:
Full agonist- and positive allosteric modulator-bound mu-type opioid receptor-G protein complex
Method: single particle / : Uchikubo-Kamo T, Shirouzu M, Hisano T, Imai S, Kaneko S, Shimada I

PDB-8k9k:
Full agonist-bound mu-type opioid receptor-G protein complex
Method: single particle / : Hisano T, Uchikubo-Kamo T, Shirouzu M, Imai S, Kaneko S, Shimada I

PDB-8k9l:
Full agonist- and positive allosteric modulator-bound mu-type opioid receptor-G protein complex
Method: single particle / : Hisano T, Uchikubo-Kamo T, Shirouzu M, Imai S, Kaneko S, Shimada I

EMDB-37640:
Cryo-EM structure of DiCas7-11 in complex with crRNA
Method: single particle / : Ma HY, Tang XD

EMDB-37649:
Cryo-EM structure of DiCas7-11-crRNA in complex with regulator
Method: single particle / : Ma HY, Tang XD

EMDB-37653:
Cryo-EM structure of DiCas7-11 mutant in complex with crRNA
Method: single particle / : Ma HY, Tang XD

EMDB-37655:
Cryo-EM structure of Cas7-11-crRNA bound to N-terminal of TPR-CHAT
Method: single particle / : Ma HY, Tang XD

PDB-8wm4:
Cryo-EM structure of DiCas7-11 in complex with crRNA
Method: single particle / : Ma HY, Tang XD

PDB-8wmc:
Cryo-EM structure of DiCas7-11-crRNA in complex with regulator
Method: single particle / : Ma HY, Tang XD

PDB-8wmi:
Cryo-EM structure of DiCas7-11 mutant in complex with crRNA
Method: single particle / : Ma HY, Tang XD

PDB-8wml:
Cryo-EM structure of Cas7-11-crRNA bound to N-terminal of TPR-CHAT
Method: single particle / : Ma HY, Tang XD

EMDB-16466:
The structural architecture of alpha-synuclein oligomer
Method: single particle / : Cuellar J, Santos J, Pallares I, Ventura S, Valpuesta JM

EMDB-16528:
3D reconstruction of alpha-synuclein oligomer-PSMa3 complex
Method: single particle / : Cuellar J, Santos J, Pallares I, Ventura S, Valpuesta JM

EMDB-19408:
Cryo-EM structure of CDK2-cyclin A in complex with CDC25A
Method: single particle / : Rowland RJ, Noble MEM, Endicott JA

EMDB-39064:
Structure of NET-Maprotiline in outward-open state
Method: single particle / : Zhang H, Xu EH, Jiang Y

EMDB-39065:
Structure of NET-Nefopam in outward-open state
Method: single particle / : Zhang H, Xu EH, Jiang Y

EMDB-39066:
Structure of NET-nomifensine in outward-open state
Method: single particle / : Zhang H, Xu EH, Jiang Y

EMDB-39067:
structure of NET-Atomoxetine in outward-open state
Method: single particle / : Zhang H, Xu EH, Jiang Y

EMDB-39068:
Structure of NET-Amitriptyline in outward-open state
Method: single particle / : Zhang H, Xu EH, Jiang Y

EMDB-39069:
Structure of Apo human norepinephrine transporter NET
Method: single particle / : Zhang H, Xu HE, Jiang Y

EMDB-39070:
Structure of NET-NE in Occluded state
Method: single particle / : Zhang H, Xu HE, Jiang Y

EMDB-39533:
Structure of NET-Nisoxetine in outward-open state
Method: single particle / : Zhang H, Xu EH, Jiang Y

EMDB-40867:
NUDT9-H domain focused cryo-EM map of TRPM2 chanzyme in the presence of Magnesium, Adenosine monophosphate, and Ribose-5-phosphate
Method: single particle / : Huang Y, Sushant K, Lu W, Du J

EMDB-44368:
Cryo-EM structure of the E396A mutant of human TRPM4 in complex with calcium at 37 degrees Celsius
Method: single particle / : Hu J, Lu W, Du J

PDB-9b94:
Cryo-EM structure of the E396A mutant of human TRPM4 in complex with calcium at 37 degrees Celsius
Method: single particle / : Hu J, Lu W, Du J

EMDB-41248:
Structure of AT118-H Nanobody Antagonist in Complex with the Angiotensin II Type I Receptor
Method: single particle / : Skiba MA, Kruse AC

EMDB-41249:
Structure of AT118-L Nanobody Antagonist in Complex with the Angiotensin II Type I Receptor and Losartan
Method: single particle / : Skiba MA, Kruse AC

PDB-8th3:
Structure of AT118-H Nanobody Antagonist in Complex with the Angiotensin II Type I Receptor
Method: single particle / : Skiba MA, Kruse AC

PDB-8th4:
Structure of AT118-L Nanobody Antagonist in Complex with the Angiotensin II Type I Receptor and Losartan
Method: single particle / : Skiba MA, Kruse AC

EMDB-36484:
Cryo-EM structure of succinate receptor bound to cis-epoxysuccinic acid coupling to Gi
Method: single particle / : Wang TX, Tang WQ, Li FH, Wang JY

EMDB-36486:
Cryo-EM structure of succinate receptor bound to succinate acid coupling MiniGsq
Method: single particle / : Wang TX, Tang WQ, Li FH, Wang JY

PDB-8jpn:
Cryo-EM structure of succinate receptor bound to cis-epoxysuccinic acid coupling to Gi
Method: single particle / : Wang TX, Tang WQ, Li FH, Wang JY

PDB-8jpp:
Cryo-EM structure of succinate receptor bound to succinate acid coupling MiniGsq
Method: single particle / : Wang TX, Tang WQ, Li FH, Wang JY

EMDB-36672:
Cryo-EM structure of the N-terminal domain of Omicron BA.1 in complex with nanobody N235 and S2L20 Fab
Method: single particle / : Liu B, Liu HH, Han P, Qi JX

PDB-8jva:
Cryo-EM structure of the N-terminal domain of Omicron BA.1 in complex with nanobody N235 and S2L20 Fab
Method: single particle / : Liu B, Liu HH, Han P, Qi JX

EMDB-39542:
CryoEM structure of fospropofol-bound MRGPRX4-Gq complex
Method: single particle / : Cao C, Fay JF, Roth BL

PDB-8yrg:
CryoEM structure of fospropofol-bound MRGPRX4-Gq complex
Method: single particle / : Cao C, Fay JF, Roth BL

EMDB-40436:
48-nm doublet microtubule from Tetrahymena thermophila strain MEC17
Method: single particle / : Black CS, Kubo S, Yang SK, Bui KH

PDB-8sf7:
48-nm doublet microtubule from Tetrahymena thermophila strain MEC17
Method: single particle / : Black CS, Kubo S, Yang SK, Bui KH

EMDB-36907:
Cryo-EM structure of the RC-LH core comples from Halorhodospira halochloris
Method: single particle / : Wang GL, Qi CH, Yu LJ

PDB-8k5o:
Cryo-EM structure of the RC-LH core comples from Halorhodospira halochloris
Method: single particle / : Wang GL, Qi CH, Yu LJ

EMDB-17356:
Structure of divisome complex FtsWIQLB
Method: single particle / : Yang L, Chang S, Tang D, Dong H, Xie T, Luo B, Lu G, Zhu X, Wei X, Dong C, Zhou R, Zhang X, Tang X

EMDB-44369:
Cryo-EM structure of the human TRPM4 channel in complex with calcium, decavanadate and ATP at 37 degrees Celsius
Method: single particle / : Hu J, Lu W, Du J

EMDB-40814:
Local refinement of SARS-CoV-2 (HP-GSAS-Mut7) spike NTD in complex with TXG-0078 Fab
Method: single particle / : Bangaru B, Ward A

EMDB-17337:
CryoEM structure of 20S Trichomonas vaginalis proteasome in complex with proteasome inhibitor CP-17
Method: single particle / : Silhan J, Boura E, Fajtova P

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Oct 5, 2021. Nobel Prize for mechanically activated and temperature-gated ion channels

Nobel Prize for mechanically activated and temperature-gated ion channels

  • The Nobel Prize in Physiology or Medicine 2021 was awarded jointly to David Julius and Ardem Patapoutian "for their discoveries of receptors for temperature and touch."
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