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Structure paper

TitleMolecular activation and G protein coupling selectivity of human succinate receptor SUCR1.
Journal, issue, pagesCell Res, Vol. 34, Issue 8, Page 590-593, Year 2024
Publish dateMay 14, 2024
AuthorsTianxin Wang / Wenqin Tang / Xiaolei Zhu / Zhenyu Lv / Jiayan Chen / Yongze Li / Xiaoyu Sun / Haoyu Lv / Quanchang Gu / Fahui Li / Jiangyun Wang /
External linksCell Res / PubMed:38744983 / PubMed Central
MethodsEM (single particle)
Resolution2.9 - 3.2 Å
Structure data

36484

8jpn

EMDB-36484, PDB-8jpn:
Cryo-EM structure of succinate receptor bound to cis-epoxysuccinic acid coupling to Gi
Method: EM (single particle) / Resolution: 2.9 Å

36486

8jpp

EMDB-36486, PDB-8jpp:
Cryo-EM structure of succinate receptor bound to succinate acid coupling MiniGsq
Method: EM (single particle) / Resolution: 3.2 Å

Chemicals

ChemComp-U9S:
(2R,3S)-oxirane-2,3-dicarboxylic acid

ChemComp-SIN:
SUCCINIC ACID

Source
  • homo sapiens (human)
  • oplophorus gracilirostris (crustacean)
  • escherichia coli (E. coli)
KeywordsMEMBRANE PROTEIN / Complex

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