2UXN | | STRUCTURAL BASIS OF HISTONE DEMETHYLATION BY LSD1 REVEALED BY SUICIDE INACTIVATION | | Descriptor: | LYSINE-SPECIFIC HISTONE DEMETHYLASE 1, REST COREPRESSOR 1, HISTONE H3.1, ... | | Authors: | Yang, M., Culhane, J.C., Szewczuk, L.M., Gocke, C.B., Brautigam, C.A., Tomchick, D.R., Machius, M., Cole, P.A., Yu, H. | | Deposit date: | 2007-03-28 | | Release date: | 2007-05-29 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.72 Å) | | Cite: | Structural Basis of Histone Demethylation by Lsd1 Revealed by Suicide Inactivation.
Nat.Struct.Mol.Biol., 14, 2007
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2UXX | | HUMAN LSD1 HISTONE DEMETHYLASE-COREST IN COMPLEX WITH AN FAD- TRANYLCYPROMINE ADDUCT | | Descriptor: | LYSINE-SPECIFIC HISTONE DEMETHYLASE 1, REST COREPRESSOR 1, FAD-trans-2-Phenylcyclopropylamine Adduct, ... | | Authors: | Yang, M., Culhane, J.C., Machius, M., Cole, P.A., Yu, H. | | Deposit date: | 2007-03-30 | | Release date: | 2007-08-21 | | Last modified: | 2019-02-06 | | Method: | X-RAY DIFFRACTION (2.74 Å) | | Cite: | Structural Basis for the Inhibition of the Lsd1 Histone Demethylase by the Antidepressant Trans-2-Phenylcyclopropylamine.
Biochemistry, 46, 2007
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2IW5 | | STRUCTURAL BASIS FOR COREST-DEPENDENT DEMETHYLATION OF NUCLEOSOMES BY THE HUMAN LSD1 HISTONE DEMETHYLASE | | Descriptor: | LYSINE-SPECIFIC HISTONE DEMETHYLASE 1, REST COREPRESSOR 1, FLAVIN-ADENINE DINUCLEOTIDE, ... | | Authors: | Yang, M., Gocke, C.B., Luo, X., Borek, D., Tomchick, D.R., Machius, M., Otwinowski, Z., Yu, H. | | Deposit date: | 2006-06-26 | | Release date: | 2006-08-09 | | Last modified: | 2019-02-06 | | Method: | X-RAY DIFFRACTION (2.57 Å) | | Cite: | Structural Basis for Corest-Dependent Demethylation of Nucleosomes by the Human Lsd1 Histone Demethylase
Mol.Cell, 23, 2006
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2VFX | | STRUCTURE OF THE SYMMETRIC MAD2 DIMER | | Descriptor: | MITOTIC SPINDLE ASSEMBLY CHECKPOINT PROTEIN MAD2A, MAGNESIUM ION, CHLORIDE ION, ... | | Authors: | Yang, M., Li, B., Liu, C.-J., Tomchick, D.R., Machius, M., Rizo, J., Yu, H., Luo, X. | | Deposit date: | 2007-11-05 | | Release date: | 2008-03-18 | | Last modified: | 2019-05-08 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | Insights Into MAD2 Regulation in the Spindle Checkpoint Revealed by the Crystal Structure of the Symmetric MAD2 Dimer.
Plos Biol., 6, 2008
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2H2N | | CRYSTAL STRUCTURE OF HUMAN SOLUBLE CALCIUM-ACTIVATED NUCLEOTIDASE (SCAN) WITH CALCIUM ION | | Descriptor: | Soluble calcium-activated nucleotidase 1, CALCIUM ION, ACETATE ION | | Authors: | Yang, M., Horii, K., Herr, A.B., Kirley, T.L. | | Deposit date: | 2006-05-19 | | Release date: | 2006-07-18 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Calcium-dependent dimerization of human soluble calcium activated nucleotidase: characterization of the dimer interface.
J.Biol.Chem., 281, 2006
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2H2U | | CRYSTAL STRUCTURE OF THE E130Y MUTANT OF HUMAN SOLUBLE CALCIUM-ACTIVATED NUCLEOTIDASE (SCAN) WITH CALCIUM ION | | Descriptor: | Soluble calcium-activated nucleotidase 1, CALCIUM ION | | Authors: | Yang, M., Horii, K., Herr, A.B., Kirley, T.L. | | Deposit date: | 2006-05-19 | | Release date: | 2006-07-18 | | Last modified: | 2017-10-18 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Calcium-dependent dimerization of human soluble calcium activated nucleotidase: characterization of the dimer interface.
J.Biol.Chem., 281, 2006
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4HY6 | | CRYSTAL STRUCTURE OF THE HUMAN HSP90-ALPHA N-DOMAIN BOUND TO THE HSP90 INHIBITOR FJ1 | | Descriptor: | Heat shock protein HSP 90-alpha, 6,6-dimethyl-3-(trifluoromethyl)-1,5,6,7-tetrahydro-4H-indazol-4-one | | Authors: | Yang, M., Li, J., He, J.H. | | Deposit date: | 2012-11-13 | | Release date: | 2013-05-15 | | Method: | X-RAY DIFFRACTION (1.649 Å) | | Cite: | Crystal Structure of the human Hsp90-alpha N-domain bound to the hsp90 inhibitor FJ1
to be published
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6PIH | | HEXAMERIC ARNA CRYO-EM STRUCTURE | | Descriptor: | Bifunctional polymyxin resistance protein ArnA, UDP-4-amino-4-deoxy-L-arabinose formyltransferase | | Authors: | Yang, M., Gehring, K. | | Deposit date: | 2019-06-26 | | Release date: | 2019-07-31 | | Last modified: | 2020-01-08 | | Method: | ELECTRON MICROSCOPY (6.6 Å) | | Cite: | Cryo-electron microscopy structures of ArnA, a key enzyme for polymyxin resistance, revealed unexpected oligomerizations and domain movements.
J.Struct.Biol., 208, 2019
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6PIK | | TETRAMERIC CRYO-EM ARNA | | Descriptor: | Bifunctional polymyxin resistance protein ArnA, UDP-4-amino-4-deoxy-L-arabinose formyltransferase | | Authors: | Yang, M., Gehring, K. | | Deposit date: | 2019-06-26 | | Release date: | 2019-07-31 | | Last modified: | 2020-01-15 | | Method: | ELECTRON MICROSCOPY (7.8 Å) | | Cite: | Cryo-electron microscopy structures of ArnA, a key enzyme for polymyxin resistance, revealed unexpected oligomerizations and domain movements.
J.Struct.Biol., 208, 2019
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4IKG | |
5I5N | |
5I5O | |
4W78 | | CRYSTAL STRUCTURE OF THE CHSH1-CHSH2 COMPLEX FROM MYCOBACTERIUM TUBERCULOSIS | | Descriptor: | Hydratase ChsH1, Hydratase ChsH2, CADMIUM ION, ... | | Authors: | Guja, K.E., Yang, M., Sampson, N., Garcia-Diaz, M. | | Deposit date: | 2014-08-21 | | Release date: | 2014-10-08 | | Last modified: | 2019-12-25 | | Method: | X-RAY DIFFRACTION (1.541 Å) | | Cite: | A Distinct MaoC-like Enoyl-CoA Hydratase Architecture Mediates Cholesterol Catabolism in Mycobacterium tuberculosis.
Acs Chem.Biol., 9, 2014
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4WNB | | CRYSTAL STRUCTURE OF THE CHSH1-CHSH2 COMPLEX FROM MYCOBACTERIUM TUBERCULOSIS BOUND TO 3-OPC-COA | | Descriptor: | Hydratase ChsH2, Hydratase ChsH1, CADMIUM ION, ... | | Authors: | Guja, K.E., Yang, M., Sampson, N., Garcia-Diaz, M. | | Deposit date: | 2014-10-11 | | Release date: | 2014-10-29 | | Last modified: | 2019-12-25 | | Method: | X-RAY DIFFRACTION (1.76 Å) | | Cite: | A Distinct MaoC-like Enoyl-CoA Hydratase Architecture Mediates Cholesterol Catabolism in Mycobacterium tuberculosis.
Acs Chem.Biol., 9, 2014
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4X28 | | CRYSTAL STRUCTURE OF THE CHSE4-CHSE5 COMPLEX FROM MYCOBACTERIUM TUBERCULOSIS | | Descriptor: | Acyl-CoA dehydrogenase, DIHYDROFLAVINE-ADENINE DINUCLEOTIDE | | Authors: | Guja, K.E., Yang, M., Sampson, N., Garcia-Diaz, M. | | Deposit date: | 2014-11-26 | | Release date: | 2015-02-18 | | Last modified: | 2019-12-18 | | Method: | X-RAY DIFFRACTION (1.99 Å) | | Cite: | Unraveling Cholesterol Catabolism in Mycobacterium tuberculosis: ChsE4-ChsE5 alpha 2 beta 2 Acyl-CoA Dehydrogenase Initiates beta-Oxidation of 3-Oxo-cholest-4-en-26-oyl CoA.
Acs Infect Dis., 1, 2015
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3T9N | | CRYSTAL STRUCTURE OF A MEMBRANE PROTEIN | | Descriptor: | Small-conductance mechanosensitive channel, DODECYL-BETA-D-MALTOSIDE | | Authors: | Yang, M., Zhang, X., Ge, J., Wang, J. | | Deposit date: | 2011-08-03 | | Release date: | 2012-10-31 | | Last modified: | 2013-06-19 | | Method: | X-RAY DIFFRACTION (3.456 Å) | | Cite: | Structure and molecular mechanism of an anion-selective mechanosensitive channel of small conductance
Proc.Natl.Acad.Sci.USA, 109, 2012
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4NQJ | | STRUCTURE OF COILED-COIL DOMAIN | | Descriptor: | E3 ubiquitin-protein ligase TRIM69, DODECYL-BETA-D-MALTOSIDE | | Authors: | Yang, M., Li, Y. | | Deposit date: | 2013-11-25 | | Release date: | 2014-05-21 | | Method: | X-RAY DIFFRACTION (2.152 Å) | | Cite: | Structural insights into the TRIM family of ubiquitin E3 ligases
Cell Res., 2014
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4PSW | | CRYSTAL STRUCTURE OF HISTONE ACETYLTRANSFERASE COMPLEX | | Descriptor: | Histone acetyltransferase type B catalytic subunit, Histone acetyltransferase type B subunit 2, Histone H4 type VIII, ... | | Authors: | Yang, M., Li, Y. | | Deposit date: | 2014-03-08 | | Release date: | 2014-07-09 | | Method: | X-RAY DIFFRACTION (2.101 Å) | | Cite: | Hat2p recognizes the histone H3 tail to specify the acetylation of the newly synthesized H3/H4 heterodimer by the Hat1p/Hat2p complex
Genes Dev., 28, 2014
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4PSX | | CRYSTAL STRUCTURE OF HISTONE ACETYLTRANSFERASE COMPLEX | | Descriptor: | Histone acetyltransferase type B catalytic subunit, Histone acetyltransferase type B subunit 2, Histone H4, ... | | Authors: | Yang, M., Li, Y. | | Deposit date: | 2014-03-08 | | Release date: | 2014-07-09 | | Method: | X-RAY DIFFRACTION (2.509 Å) | | Cite: | Hat2p recognizes the histone H3 tail to specify the acetylation of the newly synthesized H3/H4 heterodimer by the Hat1p/Hat2p complex
Genes Dev., 28, 2014
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5WY5 | | CRYSTAL STRUCTURE OF MAGEG1 AND NSE1 COMPLEX | | Descriptor: | Melanoma-associated antigen G1, Non-structural maintenance of chromosomes element 1 homolog, MAGNESIUM ION, ... | | Authors: | Yang, M., Gao, J. | | Deposit date: | 2017-01-11 | | Release date: | 2017-05-03 | | Last modified: | 2017-10-04 | | Method: | X-RAY DIFFRACTION (2.92 Å) | | Cite: | Mage-Ring Protein Complexes Comprise A Family Of E3 Ubiquitin Ligases.
Mol.Cell, 39, 2010
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5YDZ | |
5YE1 | |
5YE2 | |
5YE5 | |
1UJ1 | | CRYSTAL STRUCTURE OF SARS CORONAVIRUS MAIN PROTEINASE (3CLPRO) | | Descriptor: | 3C-like proteinase | | Authors: | Yang, H., Yang, M., Liu, Y., Bartlam, M., Ding, Y., Lou, Z., Sun, L., Zhou, Z., Ye, S., Anand, K., Pang, H., Gao, G.F., Hilgenfeld, R., Rao, Z. | | Deposit date: | 2003-07-25 | | Release date: | 2003-11-18 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | The crystal structures of severe acute respiratory syndrome virus main protease and its complex with an inhibitor
Proc.Natl.Acad.Sci.USA, 100, 2003
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