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1A43
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STRUCTURE OF THE HIV-1 CAPSID PROTEIN DIMERIZATION DOMAIN AT 2.6A RESOLUTION
分子名称:HIV-1 CAPSID
著者Worthylake, D.K., Wang, H., Yoo, S., Sundquist, W.I., Hill, C.P.
登録日1998-02-10
公開日1999-02-09
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structures of the HIV-1 capsid protein dimerization domain at 2.6 A resolution.
Acta Crystallogr.,Sect.D, 55, 1999
1AYZ
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CRYSTAL STRUCTURE OF THE SACCHAROMYCES CEREVISIAE UBIQUITIN-CONJUGATING ENZYME RAD6 (UBC2) AT 2.6A RESOLUTION
分子名称:UBIQUITIN-CONJUGATING ENZYME RAD6
著者Worthylake, D.K., Prakash, S., Prakash, L., Hill, C.P.
登録日1997-11-12
公開日1998-08-26
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Crystal structure of the Saccharomyces cerevisiae ubiquitin-conjugating enzyme Rad6 at 2.6 A resolution.
J.Biol.Chem., 273, 1998
1BAJ
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HIV-1 CAPSID PROTEIN C-TERMINAL FRAGMENT PLUS GAG P2 DOMAIN
分子名称:GAG POLYPROTEIN
著者Worthylake, D.K., Wang, H., Yoo, S., Sundquist, W.I., Hill, C.P.
登録日1998-04-17
公開日1998-10-14
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structures of the HIV-1 capsid protein dimerization domain at 2.6 A resolution.
Acta Crystallogr.,Sect.D, 55, 1999
1FOE
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CRYSTAL STRUCTURE OF RAC1 IN COMPLEX WITH THE GUANINE NUCLEOTIDE EXCHANGE REGION OF TIAM1
分子名称:T-LYMPHOMA INVASION AND METASTASIS INDUCING PROTEIN 1, RAS-RELATED C3 BOTULINUM TOXIN SUBSTRATE, SULFATE ION
著者Worthylake, D.K., Rossman, K.L., Sondek, J.
登録日2000-08-27
公開日2001-01-17
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal structure of Rac1 in complex with the guanine nucleotide exchange region of Tiam1.
Nature, 408, 2000
1RJ2
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CRYSTAL STRUCTURE OF THE DH/PH FRAGMENT OF DBS WITHOUT BOUND GTPASE
分子名称:Guanine nucleotide exchange factor DBS [Fragment]
著者Worthylake, D.K., Rossman, K.L., Sondek, J.
登録日2003-11-18
公開日2004-06-29
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Crystal structure of the DH/PH fragment of Dbs without bound GTPase.
Structure, 12, 2004
5CJP
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THE STRUCTURAL BASIS FOR CDC42-INDUCED DIMERIZATION OF IQGAPS
分子名称:Cell division cycle 42 (GTP binding protein, 25kDa), isoform CRA_a, ...
著者Worthylake, D.K., Boyapati, V.K., LeCour Jr, L.
登録日2015-07-14
公開日2016-08-10
最終更新日2017-09-20
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献The Structural Basis for Cdc42-Induced Dimerization of IQGAPs.
Structure, 24, 2016
1A8O
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HIV CAPSID C-TERMINAL DOMAIN
分子名称:HIV CAPSID
著者Gamble, T.R., Yoo, S., Vajdos, F.F., Von Schwedler, U.K., Worthylake, D.K., Wang, H., Mccutcheon, J.P., Sundquist, W.I., Hill, C.P.
登録日1998-03-27
公開日1998-10-14
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structure of the carboxyl-terminal dimerization domain of the HIV-1 capsid protein.
Science, 278, 1997
1AK4
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HUMAN CYCLOPHILIN A BOUND TO THE AMINO-TERMINAL DOMAIN OF HIV-1 CAPSID
分子名称:CYCLOPHILIN A, HIV-1 CAPSID
著者Hill, C.P., Gamble, T.R., Vajdos, F.F., Worthylake, D.K., Sundquist, W.I.
登録日1997-05-28
公開日1997-10-15
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.36 Å)
主引用文献Crystal structure of human cyclophilin A bound to the amino-terminal domain of HIV-1 capsid.
Cell(Cambridge,Mass.), 87, 1996
1AUM
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HIV CAPSID C-TERMINAL DOMAIN (CAC146)
分子名称:HIV CAPSID
著者Hill, C.P., Gamble, T.R., Yoo, S., Vajdos, F.F., Von Schwedler, U.K., Worthylake, D.K., Wang, H., Mccutcheon, J.P., Sundquist, W.I.
登録日1997-08-29
公開日1998-01-14
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structure of the carboxyl-terminal dimerization domain of the HIV-1 capsid protein.
Science, 278, 1997
1KZ7
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CRYSTAL STRUCTURE OF THE DH/PH FRAGMENT OF MURINE DBS IN COMPLEX WITH THE PLACENTAL ISOFORM OF HUMAN CDC42
分子名称:GUANINE NUCLEOTIDE EXCHANGE FACTOR DBS, CDC42 HOMOLOG
著者Rossman, K.L., Worthylake, D.K., Snyder, J.T., Siderovski, D.P., Campbell, S.L., Sondek, J.
登録日2002-02-06
公開日2002-03-20
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献A crystallographic view of interactions between Dbs and Cdc42: PH domain-assisted guanine nucleotide exchange.
EMBO J., 21, 2002
1KZG
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DBSCDC42(Y889F)
分子名称:GUANINE NUCLEOTIDE EXCHANGE FACTOR DBS, CDC42 HOMOLOG
著者Rossman, K.L., Worthylake, D.K., Snyder, J.T., Siderovski, D.P., Campbell, S.L., Sondek, J.
登録日2002-02-06
公開日2002-03-20
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献A crystallographic view of interactions between Dbs and Cdc42: PH domain-assisted guanine nucleotide exchange.
EMBO J., 21, 2002
1LB1
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CRYSTAL STRUCTURE OF THE DBL AND PLECKSTRIN HOMOLOGY DOMAINS OF DBS IN COMPLEX WITH RHOA
分子名称:Guanine nucleotide exchange factor DBS, Transforming protein RhoA
著者Snyder, J.T., Worthylake, D.K., Rossman, K.L., Betts, L., Pruitt, W.M., Siderovski, D.P., Der, C.J., Sondek, J.
登録日2002-04-01
公開日2002-05-29
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.81 Å)
主引用文献Structural basis for the selective activation of Rho GTPases by Dbl exchange factors.
Nat.Struct.Biol., 9, 2002
2NZ8
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N-TERMINAL DHPH CASSETTE OF TRIO IN COMPLEX WITH NUCLEOTIDE-FREE RAC1
分子名称:ras-related C3 botulinum toxin substrate 1 isoform Rac1, triple functional domain protein
著者Chhatriwala, M.K., Betts, L., Worthylake, D.K., Sondek, J.
登録日2006-11-22
公開日2007-04-10
最終更新日2017-10-18
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献The DH and PH Domains of Trio Coordinately Engage Rho GTPases for their Efficient Activation
J.Mol.Biol., 368, 2007
3FAY
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CRYSTAL STRUCTURE OF THE GAP-RELATED DOMAIN OF IQGAP1
分子名称:Ras GTPase-activating-like protein IQGAP1, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL
著者Kurella, V.B., Richard, J.M., Parke, C.L., Bellamy, H., Worthylake, D.K.
登録日2008-11-18
公開日2009-03-24
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal structure of the GTPase-activating protein-related domain from IQGAP1.
J.Biol.Chem., 284, 2009
3HQD
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HUMAN KINESIN EG5 MOTOR DOMAIN IN COMPLEX WITH AMPPNP AND MG2+
分子名称:Kinesin-like protein KIF11, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, PHOSPHATE ION, ...
著者Parke, C.L., Wojcik, E.J., Kim, S., Worthylake, D.K.
登録日2009-06-05
公開日2009-12-08
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.19 Å)
主引用文献ATP Hydrolysis in Eg5 Kinesin Involves a Catalytic Two-water Mechanism.
J.Biol.Chem., 285, 2010
3KEN
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HUMAN EG5 IN COMPLEX WITH S-TRITYL-L-CYSTEINE
分子名称:Kinesin-like protein KIF11, ADENOSINE-5'-DIPHOSPHATE, S-TRITYL-L-CYSTEINE, ...
著者Parke, C.L., Wojcik, E.J., Kim, S., Worthylake, D.K.
登録日2009-10-26
公開日2010-03-16
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Allosteric drug discrimination is coupled to mechanochemical changes in the kinesin-5 motor core.
J.Biol.Chem., 285, 2010
4H20
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CRYSTAL STRUCTURE AND COMPUTATIONAL MODELING OF THE FAB FRAGMENT FROM THE PROTECTIVE ANTI-RICIN MONOCLONAL ANTIBODY RAC18
分子名称:Light chain of Fab Fragment from the anti-Ricin Monoclonal Antibody RAC18, Heavy chain of Fab Fragment from the anti-Ricin Monoclonal Antibody RAC18
著者Zhao, Z., Worthylake, D.K., LeCour Jr., L.F., Maresh, G., Pincus, S.H.
登録日2012-09-11
公開日2012-10-10
最終更新日2017-11-15
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structure and computational modeling of the fab fragment from a protective anti-ricin monoclonal antibody.
Plos One, 7, 2012
5L0O
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IQGAP1 CALPONIN HOMOLOGY DOMAIN FRAGMENT (CHDF) MUTANT K161C UNDER OXIDIZING CONDITIONS
分子名称:Ras GTPase-activating-like protein IQGAP1
著者Liu, J., Worthylake, D.
登録日2016-07-27
公開日2016-09-28
最終更新日2017-11-01
実験手法X-RAY DIFFRACTION (2.36 Å)
主引用文献The IQGAP1 N-Terminus Forms Dimers, and the Dimer Interface Is Required for Binding F-Actin and Calcium-Bound Calmodulin.
Biochemistry, 55, 2016
1KI1
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GUANINE NUCLEOTIDE EXCHANGE REGION OF INTERSECTIN IN COMPLEX WITH CDC42
分子名称:G25K GTP-binding protein, placental isoform, intersectin long form, ...
著者Snyder, J.T., Pruitt, W.M., Der, C.J., Sondek, J.
登録日2001-12-02
公開日2002-05-29
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural basis for the selective activation of Rho GTPases by Dbl exchange factors.
Nat.Struct.Biol., 9, 2002
2FJU
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ACTIVATED RAC1 BOUND TO ITS EFFECTOR PHOSPHOLIPASE C BETA 2
分子名称:Ras-related C3 botulinum toxin substrate 1, 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 2, MAGNESIUM ION, ...
著者Jezyk, M.R., Snyder, J.T., Harden, T.K., Sondek, J.
登録日2006-01-03
公開日2006-11-21
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal structure of Rac1 bound to its effector phospholipase C-beta2.
Nat.Struct.Mol.Biol., 13, 2006
3I6X
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CRYSTAL STRUCTURE OF THE CALPONIN HOMOLOGY DOMAIN OF IQGAP1
分子名称:Ras GTPase-activating-like protein IQGAP1
著者Kurella, V.B.
登録日2009-07-07
公開日2010-07-21
最終更新日2017-11-01
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献The IQGAP1 N-terminus Forms Dimers and the Dimer Interface is Required for Binding F-actin and Ca2+/calmodulin.
Biochemistry, 2016
2ZKM
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CRYSTAL STRUCTURE OF PHOSPHOLIPASE C BETA 2
分子名称:1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-2, CALCIUM ION
著者Hicks, S.N., Jezyk, M.R., Gershberg, S., Seifert, J.P., Harden, T.K., Sondek, J.
登録日2008-03-26
公開日2008-08-12
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (1.62 Å)
主引用文献General and versatile autoinhibition of PLC isozymes
Mol.Cell, 31, 2008