Author results

4I9O
  • Download 4i9o
  • View 4i9o
Molmil generated image of 4i9o
CRYSTAL STRUCTURE OF GACKIX L664C TETHERED TO 1-10
Descriptor:CREB-binding protein, 1-{4-[4-chloro-3-(trifluoromethyl)phenyl]-4-hydroxypiperidin-1-yl}-3-sulfanylpropan-1-one, 1,2-ETHANEDIOL
Authors:Wang, N., Meagher, J.L., Stuckey, J.A., Mapp, A.K.
Deposit date:2012-12-05
Release date:2013-03-06
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2 Å)
Cite:Ordering a dynamic protein via a small-molecule stabilizer.
J.Am.Chem.Soc., 135, 2013
5JI8
  • Download 5ji8
  • View 5ji8
Molmil generated image of 5ji8
CRYSTAL STRUCTURE OF THE BRD9 BROMODOMAIN AND HIT 1
Descriptor:Bromodomain-containing protein 9, 2-amino-1,3-benzothiazole-6-carboxamide
Authors:Wang, N., Li, F., Bao, H., Li, J., Wu, J., Ruan, K.
Deposit date:2016-04-22
Release date:2016-06-22
Last modified:2016-08-17
Method:X-RAY DIFFRACTION (1.42 Å)
Cite:NMR Fragment Screening Hit Induces Plasticity of BRD7/9 Bromodomains
Chembiochem, 17, 2016
6A5W
  • Download 6a5w
  • View 6a5w
Molmil generated image of 6a5w
FXR-LBD WITH HNC143 AND SRC1
Descriptor:Bile acid receptor, Nuclear receptor coactivator 1, 2-[2-[[3-[2,6-bis(chloranyl)phenyl]-5-cyclopropyl-1,2-oxazol-4-yl]methoxy]-6-azaspiro[3.4]octan-6-yl]-1,3-benzothiazole-6-carboxylic acid
Authors:Wang, N., Liu, J.
Deposit date:2018-06-25
Release date:2018-10-10
Last modified:2018-12-05
Method:X-RAY DIFFRACTION (2.88 Å)
Cite:Ligand binding and heterodimerization with retinoid X receptor alpha (RXR alpha ) induce farnesoid X receptor (FXR) conformational changes affecting coactivator binding
J. Biol. Chem., 293, 2018
6A5X
  • Download 6a5x
  • View 6a5x
Molmil generated image of 6a5x
FXR-LBD WITH HNC180 AND SRC1
Descriptor:Bile acid receptor, Nuclear receptor coactivator 1, SULFATE ION, ...
Authors:Wang, N., Liu, J.
Deposit date:2018-06-25
Release date:2018-10-10
Last modified:2018-12-05
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Ligand binding and heterodimerization with retinoid X receptor alpha (RXR alpha ) induce farnesoid X receptor (FXR) conformational changes affecting coactivator binding
J. Biol. Chem., 293, 2018
6A5Y
  • Download 6a5y
  • View 6a5y
Molmil generated image of 6a5y
CRYSTAL STRUCTURE OF HUMAN FXR/RXR-LBD HETERODIMER BOUND TO HNC143 AND 9CRA AND SRC1
Descriptor:Bile acid receptor, Nuclear receptor coactivator 1, Retinoic acid receptor RXR-alpha, ...
Authors:Wang, N., Liu, J.
Deposit date:2018-06-25
Release date:2018-10-10
Last modified:2018-12-05
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Ligand binding and heterodimerization with retinoid X receptor alpha (RXR alpha ) induce farnesoid X receptor (FXR) conformational changes affecting coactivator binding
J. Biol. Chem., 293, 2018
6A5Z
  • Download 6a5z
  • View 6a5z
Molmil generated image of 6a5z
CRYSTAL STRUCTURE OF HUMAN FXR/RXR-LBD HETERODIMER BOUND TO HNC180 AND 9CRA AND SRC1
Descriptor:Bile acid receptor, Retinoic acid receptor RXR-alpha, Nuclear receptor coactivator 1, ...
Authors:Wang, N., Liu, J.
Deposit date:2018-06-25
Release date:2018-10-10
Last modified:2018-12-05
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Ligand binding and heterodimerization with retinoid X receptor alpha (RXR alpha ) induce farnesoid X receptor (FXR) conformational changes affecting coactivator binding
J. Biol. Chem., 293, 2018
6A60
  • Download 6a60
  • View 6a60
Molmil generated image of 6a60
CRYSTAL STRUCTURE OF HUMAN FXR/RXR-LBD HETERODIMER BOUND TO GW4064 AND 9CRA AND SRC1
Descriptor:Bile acid receptor, Nuclear receptor coactivator 1, Retinoic acid receptor RXR-alpha, ...
Authors:Wang, N., Liu, J.
Deposit date:2018-06-25
Release date:2018-10-10
Last modified:2018-12-05
Method:X-RAY DIFFRACTION (3.05 Å)
Cite:Ligand binding and heterodimerization with retinoid X receptor alpha (RXR alpha ) induce farnesoid X receptor (FXR) conformational changes affecting coactivator binding
J. Biol. Chem., 293, 2018
6C6Z
  • Download 6c6z
  • View 6c6z
Molmil generated image of 6c6z
CRYSTAL STRUCTURE OF POTENT NEUTRALIZING ANTIBODY CDC2-C2 IN COMPLEX WITH MERS-COV S1 RBD
Descriptor:Spike protein, Antibody CDC2-C2 heavy chain, Antibody CDC2-C2 light chain, ...
Authors:Wang, N., McLellan, J.S.
Deposit date:2018-01-19
Release date:2018-01-31
Last modified:2019-04-03
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Importance of Neutralizing Monoclonal Antibodies Targeting Multiple Antigenic Sites on the Middle East Respiratory Syndrome Coronavirus Spike Glycoprotein To Avoid Neutralization Escape.
J. Virol., 92, 2018
5VYH
  • Download 5vyh
  • View 5vyh
Molmil generated image of 5vyh
CRYSTAL STRUCTURE OF MERS-COV S1 N-TERMINAL DOMAIN
Descriptor:S protein, N-ACETYL-D-GLUCOSAMINE, FOLIC ACID, ...
Authors:Wang, N., Wrapp, D., Pallesen, J., Ward, A.B., McLellan, J.S.
Deposit date:2017-05-25
Release date:2017-08-30
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (2 Å)
Cite:Immunogenicity and structures of a rationally designed prefusion MERS-CoV spike antigen.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5VZR
  • Download 5vzr
  • View 5vzr
Molmil generated image of 5vzr
CRYSTAL STRUCTURE OF MERS-COV NEUTRALIZING ANTIBODY G4 FAB
Descriptor:G4 antibody heavy chain, G4 antibody light chain, GLYCEROL
Authors:Wang, N., Wrapp, D., McLellan, J.S.
Deposit date:2017-05-29
Release date:2017-08-30
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (1.57 Å)
Cite:Immunogenicity and structures of a rationally designed prefusion MERS-CoV spike antigen.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5ZAP
  • Download 5zap
  • View 5zap
Molmil generated image of 5zap
ATOMIC STRUCTURE OF THE HERPES SIMPLEX VIRUS TYPE 2 B-CAPSID
Descriptor:Major capsid protein, Triplex capsid protein 2, Triplex capsid protein 1, ...
Authors:Yuan, S., Wang, J.L., Zhu, D.J., Wang, N., Gao, Q., Chen, W.Y., Tang, H., Wang, J.Z., Zhang, X.Z., Liu, H.R., Rao, Z.H., Wang, X.X.
Deposit date:2018-02-08
Release date:2018-04-18
Last modified:2018-09-05
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Cryo-EM structure of a herpesvirus capsid at 3.1 angstrom.
Science, 360, 2018
5ZZ8
  • Download 5zz8
  • View 5zz8
Molmil generated image of 5zz8
STRUCTURE OF THE HERPES SIMPLEX VIRUS TYPE 2 C-CAPSID WITH CAPSID-VERTEX-SPECIFIC COMPONENT
Descriptor:VP19C, VP23, Major capsid protein, ...
Authors:Wang, J.L., Yuan, S., Zhu, D.J., Tang, H., Wang, N., Chen, W.Y., Gao, Q., Li, Y.H., Wang, J.Z., Liu, H.R., Zhang, X.Z., Rao, Z.H., Wang, X.X.
Deposit date:2018-05-31
Release date:2018-10-10
Method:ELECTRON MICROSCOPY (3.75 Å)
Cite:Structure of the herpes simplex virus type 2 C-capsid with capsid-vertex-specific component.
Nat Commun, 9, 2018
5JCP
  • Download 5jcp
  • View 5jcp
Molmil generated image of 5jcp
RHOGAP DOMAIN OF ARAP3 IN COMPLEX WITH RHOA IN THE TRANSITION STATE
Descriptor:Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3,Linker,Transforming protein RhoA, GUANOSINE-5'-DIPHOSPHATE, ...
Authors:Bao, H., Li, F., Wang, C., Wang, N., Jiang, Y., Tang, Y., Wu, J., Shi, Y.
Deposit date:2016-04-15
Release date:2016-06-22
Last modified:2016-08-17
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural Basis for the Specific Recognition of RhoA by the Dual GTPase-activating Protein ARAP3
J.Biol.Chem., 291, 2016
5WZG
  • Download 5wzg
  • View 5wzg
Molmil generated image of 5wzg
STRUCTURE OF APUM23-GAAUUGACGG
Descriptor:Pumilio homolog 23, RNA (5'-R(*GP*AP*AP*UP*UP*GP*AP*CP*GP*G)-3')
Authors:Bao, H., Wang, N., Wang, C., Jiang, Y., Wu, J., Shi, Y.
Deposit date:2017-01-18
Release date:2017-09-27
Last modified:2017-12-06
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Structural basis for the specific recognition of 18S rRNA by APUM23.
Nucleic Acids Res., 45, 2017
5WZH
  • Download 5wzh
  • View 5wzh
Molmil generated image of 5wzh
STRUCTURE OF APUM23-GGAAUUGACGG
Descriptor:Pumilio homolog 23, RNA (5'-R(*GP*GP*AP*AP*UP*UP*GP*AP*CP*GP*G)-3')
Authors:Bao, H., Wang, N., Wang, C., Jiang, Y., Wu, J., Shi, Y.
Deposit date:2017-01-18
Release date:2017-09-27
Last modified:2017-12-06
Method:X-RAY DIFFRACTION (2.509 Å)
Cite:Structural basis for the specific recognition of 18S rRNA by APUM23.
Nucleic Acids Res., 45, 2017
5WZI
  • Download 5wzi
  • View 5wzi
Molmil generated image of 5wzi
STRUCTURE OF APUM23-GGAGUUGACGG
Descriptor:Pumilio homolog 23, RNA (5'-R(*GP*GP*AP*GP*UP*UP*GP*AP*CP*GP*G)-3')
Authors:Bao, H., Wang, N., Wang, C., Jiang, Y., Wu, J., Shi, Y.
Deposit date:2017-01-18
Release date:2017-09-27
Last modified:2017-12-06
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Structural basis for the specific recognition of 18S rRNA by APUM23.
Nucleic Acids Res., 45, 2017
5WZJ
  • Download 5wzj
  • View 5wzj
Molmil generated image of 5wzj
STRUCTURE OF APUM23-GGAUUUGACGG
Descriptor:Pumilio homolog 23, RNA (5'-R(*GP*GP*AP*UP*UP*UP*GP*AP*CP*GP*G)-3')
Authors:Bao, H., Wang, N., Wang, C., Jiang, Y., Wu, J., Shi, Y.
Deposit date:2017-01-18
Release date:2017-09-27
Last modified:2017-12-06
Method:X-RAY DIFFRACTION (2.101 Å)
Cite:Structural basis for the specific recognition of 18S rRNA by APUM23.
Nucleic Acids Res., 45, 2017
5WZK
  • Download 5wzk
  • View 5wzk
Molmil generated image of 5wzk
STRUCTURE OF APUM23-DELETION-OF-INSERT-REGION-GGAAUUGACGG
Descriptor:Pumilio homolog 23, RNA (5'-R(*GP*GP*AP*AP*UP*UP*GP*AP*CP*GP*G)-3')
Authors:Bao, H., Wang, N., Wang, C., Jiang, Y., Wu, J., Shi, Y.
Deposit date:2017-01-18
Release date:2017-09-27
Last modified:2017-12-06
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural basis for the specific recognition of 18S rRNA by APUM23.
Nucleic Acids Res., 45, 2017
5XBM
  • Download 5xbm
  • View 5xbm
Molmil generated image of 5xbm
STRUCTURE OF SCARB2-JL2 COMPLEX
Descriptor:light chain of JL2, heavy chain of JL2, Lysosome membrane protein 2, ...
Authors:Zhang, X., Yang, P., Wang, N., Zhang, J., Li, J., Guo, H., Yin, X., Rao, Z., Wang, X., Zhang, L.
Deposit date:2017-03-20
Release date:2018-06-27
Method:X-RAY DIFFRACTION (3.501 Å)
Cite:The binding of a monoclonal antibody to the apical region of SCARB2 blocks EV71 infection.
Protein Cell, 8, 2017
5YWF
  • Download 5ywf
  • View 5ywf
Molmil generated image of 5ywf
CRYSTAL STRUCTURE OF 2H4 FAB
Descriptor:2H4 light chain, 2H4 heavy chain
Authors:Qiu, X., Lei, Y., Yang, P., Gao, Q., Wang, N., Cao, L., Wang, X., Xu, Z.K., Rao, Z.
Deposit date:2017-11-29
Release date:2018-03-21
Method:X-RAY DIFFRACTION (2.206 Å)
Cite:Structural basis for neutralization of Japanese encephalitis virus by two potent therapeutic antibodies
Nat Microbiol, 3, 2018
5YWO
  • Download 5ywo
  • View 5ywo
Molmil generated image of 5ywo
STRUCTURE OF JEV-2F2 FAB COMPLEX
Descriptor:JEV E protein, JEV M protein, 2F2 light chain, ...
Authors:Qiu, X., Lei, Y.F., Yang, P., Gao, Q., Wang, N., Cao, L., Yuan, S., Wang, X., Xu, Z.K., Rao, Z.
Deposit date:2017-11-29
Release date:2018-03-21
Last modified:2018-09-12
Method:ELECTRON MICROSCOPY (4.7 Å)
Cite:Structural basis for neutralization of Japanese encephalitis virus by two potent therapeutic antibodies
Nat Microbiol, 3, 2018
5YWP
  • Download 5ywp
  • View 5ywp
Molmil generated image of 5ywp
JEV-2H4 FAB COMPLEX
Descriptor:JEV E protein, JEV M protein, 2H4 light chain, ...
Authors:Qiu, X.D., Lei, Y.F., Yang, P., Gao, Q., WANG, N., Cao, L., Yuan, S., Wang, X.X., Xu, Z.K., Rao, Z.H.
Deposit date:2017-11-29
Release date:2018-05-02
Method:ELECTRON MICROSCOPY (4.6 Å)
Cite:Structural basis for neutralization of Japanese encephalitis virus by two potent therapeutic antibodies
Nat Microbiol, 3, 2018
6IQW
  • Download 6iqw
  • View 6iqw
Molmil generated image of 6iqw
CRYO-EM STRUCTURE OF CSM EFFECTOR COMPLEX
Descriptor:Csm1, Csm2, Csm3, ...
Authors:Huo, Y., Li, T., Wang, N., Dong, Q., Wang, X., Jiang, T.
Deposit date:2018-11-09
Release date:2019-01-16
Method:ELECTRON MICROSCOPY (3.35 Å)
Cite:Cryo-EM structure of Type III-A CRISPR effector complex.
Cell Res., 28, 2018
6QT9
  • Download 6qt9
  • View 6qt9
Molmil generated image of 6qt9
CRYO-EM STRUCTURE OF SH1 FULL PARTICLE.
Descriptor:ORF 25, ORF 24, ORF 31, ...
Authors:De Colibus, L., Roine, E., Walter, T.S., Ilca, S.L., Wang, X., Wang, N., Roseman, A.M., Bamford, D., Huiskonen, J.T., Stuart, D.I.
Deposit date:2019-02-22
Release date:2019-04-10
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Assembly of complex viruses exemplified by a halophilic euryarchaeal virus.
Nat Commun, 10, 2019
4FWI
  • Download 4fwi
  • View 4fwi
Molmil generated image of 4fwi
CRYSTAL STRUCTURE OF THE NUCLEOTIDE-BINDING DOMAIN OF A DIPEPTIDE ABC TRANSPORTER
Descriptor:ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component, IRON/SULFUR CLUSTER, ...
Authors:Li, X., Ge, J., Yang, M., Wang, N.
Deposit date:2012-07-01
Release date:2013-01-30
Last modified:2013-08-07
Method:X-RAY DIFFRACTION (2.892 Å)
Cite:Structure of the nucleotide-binding domain of a dipeptide ABC transporter reveals a novel iron-sulfur cluster-binding domain
Acta Crystallogr.,Sect.D, 69, 2013
<123>