4I9O | | CRYSTAL STRUCTURE OF GACKIX L664C TETHERED TO 1-10 | | Descriptor: | CREB-binding protein, 1-{4-[4-chloro-3-(trifluoromethyl)phenyl]-4-hydroxypiperidin-1-yl}-3-sulfanylpropan-1-one, 1,2-ETHANEDIOL | | Authors: | Wang, N., Meagher, J.L., Stuckey, J.A., Mapp, A.K. | | Deposit date: | 2012-12-05 | | Release date: | 2013-03-06 | | Last modified: | 2017-11-15 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Ordering a dynamic protein via a small-molecule stabilizer.
J.Am.Chem.Soc., 135, 2013
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5JI8 | | CRYSTAL STRUCTURE OF THE BRD9 BROMODOMAIN AND HIT 1 | | Descriptor: | Bromodomain-containing protein 9, 2-amino-1,3-benzothiazole-6-carboxamide | | Authors: | Wang, N., Li, F., Bao, H., Li, J., Wu, J., Ruan, K. | | Deposit date: | 2016-04-22 | | Release date: | 2016-06-22 | | Last modified: | 2016-08-17 | | Method: | X-RAY DIFFRACTION (1.42 Å) | | Cite: | NMR Fragment Screening Hit Induces Plasticity of BRD7/9 Bromodomains
Chembiochem, 17, 2016
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6A5W | | FXR-LBD WITH HNC143 AND SRC1 | | Descriptor: | Bile acid receptor, Nuclear receptor coactivator 1, 2-[2-[[3-[2,6-bis(chloranyl)phenyl]-5-cyclopropyl-1,2-oxazol-4-yl]methoxy]-6-azaspiro[3.4]octan-6-yl]-1,3-benzothiazole-6-carboxylic acid | | Authors: | Wang, N., Liu, J. | | Deposit date: | 2018-06-25 | | Release date: | 2018-10-10 | | Last modified: | 2018-12-05 | | Method: | X-RAY DIFFRACTION (2.88 Å) | | Cite: | Ligand binding and heterodimerization with retinoid X receptor alpha (RXR alpha ) induce farnesoid X receptor (FXR) conformational changes affecting coactivator binding
J. Biol. Chem., 293, 2018
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6A5X | | FXR-LBD WITH HNC180 AND SRC1 | | Descriptor: | Bile acid receptor, Nuclear receptor coactivator 1, SULFATE ION, ... | | Authors: | Wang, N., Liu, J. | | Deposit date: | 2018-06-25 | | Release date: | 2018-10-10 | | Last modified: | 2018-12-05 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Ligand binding and heterodimerization with retinoid X receptor alpha (RXR alpha ) induce farnesoid X receptor (FXR) conformational changes affecting coactivator binding
J. Biol. Chem., 293, 2018
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6A5Y | | CRYSTAL STRUCTURE OF HUMAN FXR/RXR-LBD HETERODIMER BOUND TO HNC143 AND 9CRA AND SRC1 | | Descriptor: | Bile acid receptor, Nuclear receptor coactivator 1, Retinoic acid receptor RXR-alpha, ... | | Authors: | Wang, N., Liu, J. | | Deposit date: | 2018-06-25 | | Release date: | 2018-10-10 | | Last modified: | 2018-12-05 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Ligand binding and heterodimerization with retinoid X receptor alpha (RXR alpha ) induce farnesoid X receptor (FXR) conformational changes affecting coactivator binding
J. Biol. Chem., 293, 2018
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6A5Z | | CRYSTAL STRUCTURE OF HUMAN FXR/RXR-LBD HETERODIMER BOUND TO HNC180 AND 9CRA AND SRC1 | | Descriptor: | Bile acid receptor, Retinoic acid receptor RXR-alpha, Nuclear receptor coactivator 1, ... | | Authors: | Wang, N., Liu, J. | | Deposit date: | 2018-06-25 | | Release date: | 2018-10-10 | | Last modified: | 2018-12-05 | | Method: | X-RAY DIFFRACTION (2.95 Å) | | Cite: | Ligand binding and heterodimerization with retinoid X receptor alpha (RXR alpha ) induce farnesoid X receptor (FXR) conformational changes affecting coactivator binding
J. Biol. Chem., 293, 2018
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6A60 | | CRYSTAL STRUCTURE OF HUMAN FXR/RXR-LBD HETERODIMER BOUND TO GW4064 AND 9CRA AND SRC1 | | Descriptor: | Bile acid receptor, Nuclear receptor coactivator 1, Retinoic acid receptor RXR-alpha, ... | | Authors: | Wang, N., Liu, J. | | Deposit date: | 2018-06-25 | | Release date: | 2018-10-10 | | Last modified: | 2018-12-05 | | Method: | X-RAY DIFFRACTION (3.05 Å) | | Cite: | Ligand binding and heterodimerization with retinoid X receptor alpha (RXR alpha ) induce farnesoid X receptor (FXR) conformational changes affecting coactivator binding
J. Biol. Chem., 293, 2018
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6C6Z | |
5VYH | | CRYSTAL STRUCTURE OF MERS-COV S1 N-TERMINAL DOMAIN | | Descriptor: | S protein, N-ACETYL-D-GLUCOSAMINE, FOLIC ACID, ... | | Authors: | Wang, N., Wrapp, D., Pallesen, J., Ward, A.B., McLellan, J.S. | | Deposit date: | 2017-05-25 | | Release date: | 2017-08-30 | | Last modified: | 2017-09-27 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Immunogenicity and structures of a rationally designed prefusion MERS-CoV spike antigen.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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5VZR | |
5ZAP | | ATOMIC STRUCTURE OF THE HERPES SIMPLEX VIRUS TYPE 2 B-CAPSID | | Descriptor: | Major capsid protein, Triplex capsid protein 2, Triplex capsid protein 1, ... | | Authors: | Yuan, S., Wang, J.L., Zhu, D.J., Wang, N., Gao, Q., Chen, W.Y., Tang, H., Wang, J.Z., Zhang, X.Z., Liu, H.R., Rao, Z.H., Wang, X.X. | | Deposit date: | 2018-02-08 | | Release date: | 2018-04-18 | | Last modified: | 2018-09-05 | | Method: | ELECTRON MICROSCOPY (3.1 Å) | | Cite: | Cryo-EM structure of a herpesvirus capsid at 3.1 angstrom.
Science, 360, 2018
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5ZZ8 | | STRUCTURE OF THE HERPES SIMPLEX VIRUS TYPE 2 C-CAPSID WITH CAPSID-VERTEX-SPECIFIC COMPONENT | | Descriptor: | VP19C, VP23, Major capsid protein, ... | | Authors: | Wang, J.L., Yuan, S., Zhu, D.J., Tang, H., Wang, N., Chen, W.Y., Gao, Q., Li, Y.H., Wang, J.Z., Liu, H.R., Zhang, X.Z., Rao, Z.H., Wang, X.X. | | Deposit date: | 2018-05-31 | | Release date: | 2018-10-10 | | Method: | ELECTRON MICROSCOPY (3.75 Å) | | Cite: | Structure of the herpes simplex virus type 2 C-capsid with capsid-vertex-specific component.
Nat Commun, 9, 2018
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5JCP | | RHOGAP DOMAIN OF ARAP3 IN COMPLEX WITH RHOA IN THE TRANSITION STATE | | Descriptor: | Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3,Linker,Transforming protein RhoA, GUANOSINE-5'-DIPHOSPHATE, ... | | Authors: | Bao, H., Li, F., Wang, C., Wang, N., Jiang, Y., Tang, Y., Wu, J., Shi, Y. | | Deposit date: | 2016-04-15 | | Release date: | 2016-06-22 | | Last modified: | 2016-08-17 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Structural Basis for the Specific Recognition of RhoA by the Dual GTPase-activating Protein ARAP3
J.Biol.Chem., 291, 2016
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5WZG | | STRUCTURE OF APUM23-GAAUUGACGG | | Descriptor: | Pumilio homolog 23, RNA (5'-R(*GP*AP*AP*UP*UP*GP*AP*CP*GP*G)-3') | | Authors: | Bao, H., Wang, N., Wang, C., Jiang, Y., Wu, J., Shi, Y. | | Deposit date: | 2017-01-18 | | Release date: | 2017-09-27 | | Last modified: | 2017-12-06 | | Method: | X-RAY DIFFRACTION (2.55 Å) | | Cite: | Structural basis for the specific recognition of 18S rRNA by APUM23.
Nucleic Acids Res., 45, 2017
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5WZH | | STRUCTURE OF APUM23-GGAAUUGACGG | | Descriptor: | Pumilio homolog 23, RNA (5'-R(*GP*GP*AP*AP*UP*UP*GP*AP*CP*GP*G)-3') | | Authors: | Bao, H., Wang, N., Wang, C., Jiang, Y., Wu, J., Shi, Y. | | Deposit date: | 2017-01-18 | | Release date: | 2017-09-27 | | Last modified: | 2017-12-06 | | Method: | X-RAY DIFFRACTION (2.509 Å) | | Cite: | Structural basis for the specific recognition of 18S rRNA by APUM23.
Nucleic Acids Res., 45, 2017
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5WZI | | STRUCTURE OF APUM23-GGAGUUGACGG | | Descriptor: | Pumilio homolog 23, RNA (5'-R(*GP*GP*AP*GP*UP*UP*GP*AP*CP*GP*G)-3') | | Authors: | Bao, H., Wang, N., Wang, C., Jiang, Y., Wu, J., Shi, Y. | | Deposit date: | 2017-01-18 | | Release date: | 2017-09-27 | | Last modified: | 2017-12-06 | | Method: | X-RAY DIFFRACTION (2.75 Å) | | Cite: | Structural basis for the specific recognition of 18S rRNA by APUM23.
Nucleic Acids Res., 45, 2017
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5WZJ | | STRUCTURE OF APUM23-GGAUUUGACGG | | Descriptor: | Pumilio homolog 23, RNA (5'-R(*GP*GP*AP*UP*UP*UP*GP*AP*CP*GP*G)-3') | | Authors: | Bao, H., Wang, N., Wang, C., Jiang, Y., Wu, J., Shi, Y. | | Deposit date: | 2017-01-18 | | Release date: | 2017-09-27 | | Last modified: | 2017-12-06 | | Method: | X-RAY DIFFRACTION (2.101 Å) | | Cite: | Structural basis for the specific recognition of 18S rRNA by APUM23.
Nucleic Acids Res., 45, 2017
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5WZK | | STRUCTURE OF APUM23-DELETION-OF-INSERT-REGION-GGAAUUGACGG | | Descriptor: | Pumilio homolog 23, RNA (5'-R(*GP*GP*AP*AP*UP*UP*GP*AP*CP*GP*G)-3') | | Authors: | Bao, H., Wang, N., Wang, C., Jiang, Y., Wu, J., Shi, Y. | | Deposit date: | 2017-01-18 | | Release date: | 2017-09-27 | | Last modified: | 2017-12-06 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Structural basis for the specific recognition of 18S rRNA by APUM23.
Nucleic Acids Res., 45, 2017
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5XBM | | STRUCTURE OF SCARB2-JL2 COMPLEX | | Descriptor: | light chain of JL2, heavy chain of JL2, Lysosome membrane protein 2, ... | | Authors: | Zhang, X., Yang, P., Wang, N., Zhang, J., Li, J., Guo, H., Yin, X., Rao, Z., Wang, X., Zhang, L. | | Deposit date: | 2017-03-20 | | Release date: | 2018-06-27 | | Method: | X-RAY DIFFRACTION (3.501 Å) | | Cite: | The binding of a monoclonal antibody to the apical region of SCARB2 blocks EV71 infection.
Protein Cell, 8, 2017
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5YWF | | CRYSTAL STRUCTURE OF 2H4 FAB | | Descriptor: | 2H4 light chain, 2H4 heavy chain | | Authors: | Qiu, X., Lei, Y., Yang, P., Gao, Q., Wang, N., Cao, L., Wang, X., Xu, Z.K., Rao, Z. | | Deposit date: | 2017-11-29 | | Release date: | 2018-03-21 | | Method: | X-RAY DIFFRACTION (2.206 Å) | | Cite: | Structural basis for neutralization of Japanese encephalitis virus by two potent therapeutic antibodies
Nat Microbiol, 3, 2018
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5YWO | | STRUCTURE OF JEV-2F2 FAB COMPLEX | | Descriptor: | JEV E protein, JEV M protein, 2F2 light chain, ... | | Authors: | Qiu, X., Lei, Y.F., Yang, P., Gao, Q., Wang, N., Cao, L., Yuan, S., Wang, X., Xu, Z.K., Rao, Z. | | Deposit date: | 2017-11-29 | | Release date: | 2018-03-21 | | Last modified: | 2018-09-12 | | Method: | ELECTRON MICROSCOPY (4.7 Å) | | Cite: | Structural basis for neutralization of Japanese encephalitis virus by two potent therapeutic antibodies
Nat Microbiol, 3, 2018
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5YWP | | JEV-2H4 FAB COMPLEX | | Descriptor: | JEV E protein, JEV M protein, 2H4 light chain, ... | | Authors: | Qiu, X.D., Lei, Y.F., Yang, P., Gao, Q., WANG, N., Cao, L., Yuan, S., Wang, X.X., Xu, Z.K., Rao, Z.H. | | Deposit date: | 2017-11-29 | | Release date: | 2018-05-02 | | Method: | ELECTRON MICROSCOPY (4.6 Å) | | Cite: | Structural basis for neutralization of Japanese encephalitis virus by two potent therapeutic antibodies
Nat Microbiol, 3, 2018
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6IQW | | CRYO-EM STRUCTURE OF CSM EFFECTOR COMPLEX | | Descriptor: | Csm1, Csm2, Csm3, ... | | Authors: | Huo, Y., Li, T., Wang, N., Dong, Q., Wang, X., Jiang, T. | | Deposit date: | 2018-11-09 | | Release date: | 2019-01-16 | | Method: | ELECTRON MICROSCOPY (3.35 Å) | | Cite: | Cryo-EM structure of Type III-A CRISPR effector complex.
Cell Res., 28, 2018
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6QT9 | | CRYO-EM STRUCTURE OF SH1 FULL PARTICLE. | | Descriptor: | ORF 25, ORF 24, ORF 31, ... | | Authors: | De Colibus, L., Roine, E., Walter, T.S., Ilca, S.L., Wang, X., Wang, N., Roseman, A.M., Bamford, D., Huiskonen, J.T., Stuart, D.I. | | Deposit date: | 2019-02-22 | | Release date: | 2019-04-10 | | Method: | ELECTRON MICROSCOPY (3.8 Å) | | Cite: | Assembly of complex viruses exemplified by a halophilic euryarchaeal virus.
Nat Commun, 10, 2019
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4FWI | | CRYSTAL STRUCTURE OF THE NUCLEOTIDE-BINDING DOMAIN OF A DIPEPTIDE ABC TRANSPORTER | | Descriptor: | ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component, IRON/SULFUR CLUSTER, ... | | Authors: | Li, X., Ge, J., Yang, M., Wang, N. | | Deposit date: | 2012-07-01 | | Release date: | 2013-01-30 | | Last modified: | 2013-08-07 | | Method: | X-RAY DIFFRACTION (2.892 Å) | | Cite: | Structure of the nucleotide-binding domain of a dipeptide ABC transporter reveals a novel iron-sulfur cluster-binding domain
Acta Crystallogr.,Sect.D, 69, 2013
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