4I9O
Crystal Structure of GACKIX L664C Tethered to 1-10
Summary for 4I9O
Entry DOI | 10.2210/pdb4i9o/pdb |
Descriptor | CREB-binding protein, 1-{4-[4-chloro-3-(trifluoromethyl)phenyl]-4-hydroxypiperidin-1-yl}-3-sulfanylpropan-1-one, 1,2-ETHANEDIOL, ... (4 entities in total) |
Functional Keywords | kix domain, transcriptional coactivator, transferase |
Biological source | Mus musculus (mouse) |
Cellular location | Cytoplasm : P45481 |
Total number of polymer chains | 1 |
Total formula weight | 12631.18 |
Authors | Wang, N.,Meagher, J.L.,Stuckey, J.A.,Mapp, A.K. (deposition date: 2012-12-05, release date: 2013-03-06, Last modification date: 2017-11-15) |
Primary citation | Wang, N.,Majmudar, C.Y.,Pomerantz, W.C.,Gagnon, J.K.,Sadowsky, J.D.,Meagher, J.L.,Johnson, T.K.,Stuckey, J.A.,Brooks, C.L.,Wells, J.A.,Mapp, A.K. Ordering a dynamic protein via a small-molecule stabilizer. J.Am.Chem.Soc., 135:3363-3366, 2013 Cited by PubMed: 23384013DOI: 10.1021/ja3122334 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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