6J4Q
Structural basis of tubulin detyrosination by vasohibins-SVBP enzyme complex and functional implications
Summary for 6J4Q
Entry DOI | 10.2210/pdb6j4q/pdb |
Descriptor | Tubulinyl-Tyr carboxypeptidase 2, Small vasohibin-binding protein, N-[(2S)-4-chloro-3-oxo-1-phenyl-butan-2-yl]-4-methyl-benzenesulfonamide, ... (5 entities in total) |
Functional Keywords | carboxypeptidase, tubulin, microtubule, inhibitor, tpck, hydrolase |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 8 |
Total formula weight | 151149.00 |
Authors | |
Primary citation | Wang, N.,Bosc, C.,Ryul Choi, S.,Boulan, B.,Peris, L.,Olieric, N.,Bao, H.,Krichen, F.,Chen, L.,Andrieux, A.,Olieric, V.,Moutin, M.J.,Steinmetz, M.O.,Huang, H. Structural basis of tubulin detyrosination by the vasohibin-SVBP enzyme complex. Nat.Struct.Mol.Biol., 26:571-582, 2019 Cited by PubMed: 31235911DOI: 10.1038/s41594-019-0241-y PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.7 Å) |
Structure validation
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