6J4P
Structural basis of tubulin detyrosination by vasohibins-SVBP enzyme complex and functional implications
Summary for 6J4P
Entry DOI | 10.2210/pdb6j4p/pdb |
Descriptor | Tubulinyl-Tyr carboxypeptidase 2, Small vasohibin-binding protein, N-[(3R)-4-ethoxy-3-hydroxy-4-oxobutanoyl]-L-tyrosine, ... (4 entities in total) |
Functional Keywords | carboxypeptidase, tubulin, microtubule, inhibitor, epoy, hydrolase |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 2 |
Total formula weight | 37469.67 |
Authors | |
Primary citation | Wang, N.,Bosc, C.,Ryul Choi, S.,Boulan, B.,Peris, L.,Olieric, N.,Bao, H.,Krichen, F.,Chen, L.,Andrieux, A.,Olieric, V.,Moutin, M.J.,Steinmetz, M.O.,Huang, H. Structural basis of tubulin detyrosination by the vasohibin-SVBP enzyme complex. Nat.Struct.Mol.Biol., 26:571-582, 2019 Cited by PubMed: 31235911DOI: 10.1038/s41594-019-0241-y PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.599 Å) |
Structure validation
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