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6J4P

Structural basis of tubulin detyrosination by vasohibins-SVBP enzyme complex and functional implications

Functional Information from GO Data
ChainGOidnamespacecontents
A0005737cellular_componentcytoplasm
A0045765biological_processregulation of angiogenesis
B0005515molecular_functionprotein binding
B0005576cellular_componentextracellular region
B0005737cellular_componentcytoplasm
B0005856cellular_componentcytoskeleton
B0006508biological_processproteolysis
B0008017molecular_functionmicrotubule binding
B0009306biological_processprotein secretion
B0010596biological_processnegative regulation of endothelial cell migration
B0016504molecular_functionpeptidase activator activity
B0031397biological_processnegative regulation of protein ubiquitination
B0045177cellular_componentapical part of cell
B0061564biological_processaxon development
B1905048biological_processregulation of metallopeptidase activity
Functional Information from PDB Data
site_idAC1
Number of Residues15
Detailsbinding site for residue BJL A 900
ChainResidue
APHE49
AARG211
AHIS241
AHOH1016
AHOH1036
AHOH1064
AHOH1145
ATYR123
ALYS157
ACYS158
ALEU159
APHE191
AHIS192
AHIS193
ASER210

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues1
DetailsACT_SITE: ACT_SITE => ECO:0000269|PubMed:29146869, ECO:0000305|PubMed:26794318
ChainResidueDetails
ACYS158

site_idSWS_FT_FI2
Number of Residues2
DetailsACT_SITE: ACT_SITE => ECO:0000305|PubMed:26794318
ChainResidueDetails
AHIS193
ASER210

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PDB entries from 2024-07-10

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