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4A4C
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BU of 4a4c by Molmil
Structure of phosphoTyr371-c-Cbl-UbcH5B-ZAP-70 complex
Descriptor: CALCIUM ION, E3 UBIQUITIN-PROTEIN LIGASE CBL, TYROSINE-PROTEIN KINASE ZAP-70, ...
Authors:Dou, H, Buetow, L, Hock, A, Sibbet, G.J, Vousden, K.H, Huang, D.T.
Deposit date:2011-10-08
Release date:2012-01-25
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.704 Å)
Cite:Structural Basis for Autoinhibition and Phosphorylation-Dependent Activation of C-Cbl
Nat.Struct.Mol.Biol., 19, 2012
4A4B
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BU of 4a4b by Molmil
Structure of modified phosphoTyr371-c-Cbl-UbcH5B-ZAP-70 complex
Descriptor: CALCIUM ION, E3 UBIQUITIN-PROTEIN LIGASE CBL, TYROSINE-PROTEIN KINASE ZAP-70, ...
Authors:Dou, H, Buetow, L, Hock, A, Sibbet, G.J, Vousden, K.H, Huang, D.T.
Deposit date:2011-10-08
Release date:2012-01-25
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.789 Å)
Cite:Structural Basis for Autoinhibition and Phosphorylation-Dependent Activation of C-Cbl
Nat.Struct.Mol.Biol., 19, 2012
4B2D
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BU of 4b2d by Molmil
human PKM2 with L-serine and FBP bound.
Descriptor: 1,6-di-O-phosphono-beta-D-fructofuranose, MAGNESIUM ION, PYRUVATE KINASE ISOZYMES M1/M2, ...
Authors:Chaneton, B, Hillmann, P, Zheng, L, Martin, A.C.L, Maddocks, O.D.K, Chokkathukalam, A, Coyle, J.E, Jankevics, A, Holding, F.P, Vousden, K.H, Frezza, C, O'Reilly, M, Gottlieb, E.
Deposit date:2012-07-13
Release date:2012-10-10
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Serine is a natural ligand and allosteric activator of pyruvate kinase M2.
Nature, 491, 2012
4A49
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BU of 4a49 by Molmil
Structure of phosphoTyr371-c-Cbl-UbcH5B complex
Descriptor: E3 ubiquitin-protein ligase CBL, POTASSIUM ION, Ubiquitin-conjugating enzyme E2 D2, ...
Authors:Dou, H, Buetow, L, Hock, A, Sibbet, G.J, Vousden, K.H, Huang, D.T.
Deposit date:2011-10-07
Release date:2012-01-25
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.214 Å)
Cite:Structural basis for autoinhibition and phosphorylation-dependent activation of c-Cbl.
Nat. Struct. Mol. Biol., 19, 2012
5MNJ
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BU of 5mnj by Molmil
Structure of MDM2-MDMX-UbcH5B-ubiquitin complex
Descriptor: E3 ubiquitin-protein ligase Mdm2, Polyubiquitin-B, Protein Mdm4, ...
Authors:Klejnot, M, Huang, D.T.
Deposit date:2016-12-13
Release date:2017-05-31
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.16 Å)
Cite:Structural analysis of MDM2 RING separates degradation from regulation of p53 transcription activity.
Nat. Struct. Mol. Biol., 24, 2017
2Y1M
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BU of 2y1m by Molmil
Structure of native c-Cbl
Descriptor: CALCIUM ION, E3 UBIQUITIN-PROTEIN LIGASE, ZINC ION
Authors:Dou, H, Sibbet, G.J, Huang, D.T.
Deposit date:2010-12-08
Release date:2012-01-18
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.67 Å)
Cite:Structural Basis for Autoinhibition and Phosphorylation-Dependent Activation of C-Cbl.
Nat.Struct.Mol.Biol., 19, 2012
2Y1N
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BU of 2y1n by Molmil
Structure of c-Cbl-ZAP-70 peptide complex
Descriptor: CALCIUM ION, E3 UBIQUITIN-PROTEIN LIGASE, TYROSINE-PROTEIN KINASE ZAP-70 ZAP-70,70 KDA ZETA-ASSOCIATED PROTEIN, ...
Authors:Dou, H, Sibbet, G.J, Huang, D.T.
Deposit date:2010-12-08
Release date:2012-01-18
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.999 Å)
Cite:Structural Basis for Autoinhibition and Phosphorylation-Dependent Activation of C-Cbl.
Nat.Struct.Mol.Biol., 19, 2012
6SQO
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BU of 6sqo by Molmil
Crystal structure of human MDM2 RING domain homodimer bound to UbcH5B-Ub
Descriptor: CHLORIDE ION, E3 ubiquitin-protein ligase Mdm2, NITRATE ION, ...
Authors:Magnussen, H.M, Ahmed, S.F, Huang, D.T.
Deposit date:2019-09-04
Release date:2020-05-06
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.41 Å)
Cite:Structural basis for DNA damage-induced phosphoregulation of MDM2 RING domain.
Nat Commun, 11, 2020
6SQR
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BU of 6sqr by Molmil
Crystal structure of Cat MDM2-S429E RING domain bound to UbcH5B-Ub
Descriptor: 1,2-ETHANEDIOL, E3 ubiquitin-protein ligase Mdm2, NITRATE ION, ...
Authors:Magnussen, H.M, Ahmed, S.F, Huang, D.T.
Deposit date:2019-09-04
Release date:2020-05-06
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.18 Å)
Cite:Structural basis for DNA damage-induced phosphoregulation of MDM2 RING domain.
Nat Commun, 11, 2020
6SQP
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BU of 6sqp by Molmil
Crystal structure of Cat MDM2-S429E RING domain homodimer
Descriptor: CHLORIDE ION, E3 ubiquitin-protein ligase Mdm2, NITRATE ION, ...
Authors:Magnussen, H.M, Ahmed, S.F, Huang, D.T.
Deposit date:2019-09-04
Release date:2020-05-06
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.21 Å)
Cite:Structural basis for DNA damage-induced phosphoregulation of MDM2 RING domain.
Nat Commun, 11, 2020
6SQS
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BU of 6sqs by Molmil
Crystal structure of cat phospho-Ser429 MDM2 RING domain bound to UbcH5B-Ub
Descriptor: E3 ubiquitin-protein ligase Mdm2, Ubiquitin-40S ribosomal protein S27a, Ubiquitin-conjugating enzyme E2 D2, ...
Authors:Magnussen, H.M, Ahmed, S.F, Huang, D.T.
Deposit date:2019-09-04
Release date:2020-05-06
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.83 Å)
Cite:Structural basis for DNA damage-induced phosphoregulation of MDM2 RING domain.
Nat Commun, 11, 2020

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