Author results

3J9M
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STRUCTURE OF THE HUMAN MITOCHONDRIAL RIBOSOME (CLASS 1)
Descriptor:16S rRNA, mt-tRNAVal, uL2m, ...
Authors:Amunts, A., Brown, A., Toots, J., Scheres, S.H., Ramakrishnan, V.
Deposit date:2015-02-08
Release date:2015-04-15
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Ribosome. The structure of the human mitochondrial ribosome.
Science, 348, 2015
5GAN
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THE OVERALL STRUCTURE OF THE YEAST SPLICEOSOMAL U4/U6.U5 TRI-SNRNP AT 3.7 ANGSTROM
Descriptor:U4 snRNA, U6 snRNA, Pre-mRNA-splicing factor 8, ...
Authors:Nguyen, T.H.D., Galej, W.P., Bai, X.C., Oubridge, C., Scheres, S.H.W., Newman, A.J., Nagai, K.
Deposit date:2015-12-15
Release date:2016-01-27
Last modified:2019-02-20
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Cryo-EM structure of the yeast U4/U6.U5 tri-snRNP at 3.7 angstrom resolution.
Nature, 530, 2016
5GAO
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HEAD REGION OF THE YEAST SPLICEOSOMAL U4/U6.U5 TRI-SNRNP
Descriptor:Small nuclear ribonucleoprotein-associated protein B, Small nuclear ribonucleoprotein Sm D1, Small nuclear ribonucleoprotein Sm D2, ...
Authors:Nguyen, T.H.D., Galej, W.P., Bai, X.C., Oubridge, C., Scheres, S.H.W., Newman, A.J., Nagai, K.
Deposit date:2015-12-15
Release date:2016-01-27
Last modified:2018-10-03
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Cryo-EM structure of the yeast U4/U6.U5 tri-snRNP at 3.7 angstrom resolution.
Nature, 530, 2016
3J6B
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STRUCTURE OF THE YEAST MITOCHONDRIAL LARGE RIBOSOMAL SUBUNIT
Descriptor:21S ribosomal RNA, 54S ribosomal protein RML2, mitochondrial, ...
Authors:Amunts, A., Brown, A., Bai, X.C., Llacer, J.L., Hussain, T., Emsley, P., Long, F., Murshudov, G., Scheres, S.H.W., Ramakrishnan, V.
Deposit date:2014-01-22
Release date:2014-04-09
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Structure of the yeast mitochondrial large ribosomal subunit.
Science, 343, 2014
3J79
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CRYO-EM STRUCTURE OF THE PLASMODIUM FALCIPARUM 80S RIBOSOME BOUND TO THE ANTI-PROTOZOAN DRUG EMETINE, LARGE SUBUNIT
Descriptor:28S ribosomal RNA, 5S ribosomal RNA, 5.8S ribosomal RNA, ...
Authors:Wong, W., Bai, X.C., Brown, A., Fernandez, I.S., Hanssen, E., Condron, M., Tan, Y.H., Baum, J., Scheres, S.H.W.
Deposit date:2014-06-02
Release date:2014-07-16
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Cryo-EM structure of the Plasmodium falciparum 80S ribosome bound to the anti-protozoan drug emetine.
Elife, 3, 2014
3J7A
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CRYO-EM STRUCTURE OF THE PLASMODIUM FALCIPARUM 80S RIBOSOME BOUND TO THE ANTI-PROTOZOAN DRUG EMETINE, SMALL SUBUNIT
Descriptor:18S ribosomal RNA, 40S ribosomal protein eS1, 40S ribosomal protein uS2, ...
Authors:Wong, W., Bai, X.C., Brown, A., Fernandez, I.S., Hanssen, E., Condron, M., Tan, Y.H., Baum, J., Scheres, S.H.W.
Deposit date:2014-06-03
Release date:2014-07-16
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Cryo-EM structure of the Plasmodium falciparum 80S ribosome bound to the anti-protozoan drug emetine.
Elife, 3, 2014
3J7O
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STRUCTURE OF THE MAMMALIAN 60S RIBOSOMAL SUBUNIT
Descriptor:28S ribosomal RNA, 5S ribosomal RNA, 5.8S ribosomal RNA, ...
Authors:Voorhees, R.M., Fernandez, I.S., Scheres, S.H.W., Hegde, R.S.
Deposit date:2014-08-01
Release date:2014-09-03
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Structure of the Mammalian ribosome-sec61 complex to 3.4 a resolution.
Cell(Cambridge,Mass.), 157, 2014
3J7P
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STRUCTURE OF THE 80S MAMMALIAN RIBOSOME BOUND TO EEF2
Descriptor:28S ribosomal RNA, 5S ribosomal RNA, 5.8S ribosomal RNA, ...
Authors:Voorhees, R.M., Fernandez, I.S., Scheres, S.H.W., Hegde, R.S.
Deposit date:2014-08-01
Release date:2014-09-03
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Structure of the Mammalian ribosome-sec61 complex to 3.4 a resolution.
Cell(Cambridge,Mass.), 157, 2014
3J7Q
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STRUCTURE OF THE IDLE MAMMALIAN RIBOSOME-SEC61 COMPLEX
Descriptor:28S ribosomal RNA, 5S ribosomal RNA, 5.8S ribosomal RNA, ...
Authors:Voorhees, R.M., Fernandez, I.S., Scheres, S.H.W., Hegde, R.S.
Deposit date:2014-08-01
Release date:2014-09-03
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Structure of the Mammalian ribosome-sec61 complex to 3.4 a resolution.
Cell(Cambridge,Mass.), 157, 2014
3J7R
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STRUCTURE OF THE TRANSLATING MAMMALIAN RIBOSOME-SEC61 COMPLEX
Descriptor:28S ribosomal RNA, 5S ribosomal RNA, 5.8S ribosomal RNA, ...
Authors:Voorhees, R.M., Fernandez, I.S., Scheres, S.H.W., Hegde, R.S.
Deposit date:2014-08-01
Release date:2014-09-03
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Structure of the Mammalian ribosome-sec61 complex to 3.4 a resolution.
Cell(Cambridge,Mass.), 157, 2014
3J7Y
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STRUCTURE OF THE LARGE RIBOSOMAL SUBUNIT FROM HUMAN MITOCHONDRIA
Descriptor:16S rRNA, mt-tRNAVal, uL2, ...
Authors:Brown, A., Amunts, A., Bai, X.C., Sugimoto, Y., Edwards, P.C., Murshudov, G., Scheres, S.H.W., Ramakrishnan, V.
Deposit date:2014-08-26
Release date:2014-10-15
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structure of the large ribosomal subunit from human mitochondria.
Science, 346, 2014
3J8H
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STRUCTURE OF THE RABBIT RYANODINE RECEPTOR RYR1 IN COMPLEX WITH FKBP12 AT 3.8 ANGSTROM RESOLUTION
Descriptor:Ryanodine receptor 1, Peptidyl-prolyl cis-trans isomerase FKBP1A, ZINC ION
Authors:Yan, Z., Bai, X., Yan, C., Wu, J., Scheres, S.H.W., Shi, Y., Yan, N.
Deposit date:2014-10-26
Release date:2014-12-10
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Structure of the rabbit ryanodine receptor RyR1 at near-atomic resolution.
Nature, 517, 2015
3J9K
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STRUCTURE OF DARK APOPTOSOME IN COMPLEX WITH DRONC CARD DOMAIN
Descriptor:Apaf-1 related killer DARK, Caspase Nc, ADENOSINE-5'-DIPHOSPHATE
Authors:Pang, Y., Bai, X., Yan, C., Hao, Q., Chen, Z., Wang, J., Scheres, S.H.W., Shi, Y.
Deposit date:2015-02-04
Release date:2015-02-25
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Structure of the apoptosome: mechanistic insights into activation of an initiator caspase from Drosophila.
Genes Dev., 29, 2015
3J9L
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STRUCTURE OF DARK APOPTOSOME FROM DROSOPHILA MELANOGASTER
Descriptor:Apaf-1 related killer DARK, 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE
Authors:Pang, Y., Bai, X., Yan, C., Hao, Q., Chen, Z., Wang, J., Scheres, S.H.W., Shi, Y.
Deposit date:2015-02-04
Release date:2015-02-25
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Structure of the apoptosome: mechanistic insights into activation of an initiator caspase from Drosophila.
Genes Dev., 29, 2015
5FKU
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CRYO-EM STRUCTURE OF THE E. COLI REPLICATIVE DNA POLYMERASE COMPLEX IN DNA FREE STATE (DNA POLYMERASE III ALPHA, BETA, EPSILON, TAU COMPLEX)
Descriptor:DNA POLYMERASE III SUBUNIT ALPHA, DNA POLYMERASE III SUBUNIT BETA, DNA POLYMERASE III SUBUNIT EPSILON, ...
Authors:Fernandez-Leiro, R., Conrad, J., Scheres, S.H.W., Lamers, M.H.
Deposit date:2015-10-20
Release date:2015-11-25
Last modified:2019-02-27
Method:ELECTRON MICROSCOPY (8.34 Å)
Cite:cryo-EM structures of theE. colireplicative DNA polymerase reveal its dynamic interactions with the DNA sliding clamp, exonuclease andtau.
Elife, 4, 2015
5FKV
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CRYO-EM STRUCTURE OF THE E. COLI REPLICATIVE DNA POLYMERASE COMPLEX BOUND TO DNA (DNA POLYMERASE III ALPHA, BETA, EPSILON, TAU COMPLEX)
Descriptor:DNA POLYMERASE III SUBUNIT ALPHA, DNA POLYMERASE III BETA, DNA POLYMERASE III EPSILON, ...
Authors:Fernandez-Leiro, R., Conrad, J., Scheres, S.H.W., Lamers, M.H.
Deposit date:2015-10-20
Release date:2015-11-25
Last modified:2019-02-27
Method:ELECTRON MICROSCOPY (8 Å)
Cite:cryo-EM structures of theE. colireplicative DNA polymerase reveal its dynamic interactions with the DNA sliding clamp, exonuclease andtau.
Elife, 4, 2015
5FKW
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CRYO-EM STRUCTURE OF THE E. COLI REPLICATIVE DNA POLYMERASE COMPLEX BOUND TO DNA (DNA POLYMERASE III ALPHA, BETA, EPSILON)
Descriptor:DNA POLYMERASE III ALPHA, DNA POLYMERASE III BETA, DNA POLYMERASE III EPSILON, ...
Authors:Fernandez-Leiro, R., Conrad, J., Scheres, S.H.W., Lamers, M.H.
Deposit date:2015-10-20
Release date:2015-11-25
Last modified:2019-02-27
Method:ELECTRON MICROSCOPY (7.3 Å)
Cite:cryo-EM structures of theE. colireplicative DNA polymerase reveal its dynamic interactions with the DNA sliding clamp, exonuclease andtau.
Elife, 4, 2015
5FN2
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CRYO-EM STRUCTURE OF GAMMA SECRETASE IN COMPLEX WITH A DRUG DAPT
Descriptor:NICASTRIN, PRESENILIN-1, GAMMA-SECRETASE SUBUNIT APH-1A, ...
Authors:Bai, X.C., Rajendra, E., Yang, G.H., Shi, Y.G., Scheres, S.H.W.
Deposit date:2015-11-10
Release date:2015-12-16
Last modified:2016-12-21
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Sampling the conformational space of the catalytic subunit of human gamma-secretase.
Elife, 4, 2015
5FN3
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CRYO-EM STRUCTURE OF GAMMA SECRETASE IN CLASS 1 OF THE APO- STATE ENSEMBLE
Descriptor:NICASTRIN, PRESENILIN-1, GAMMA-SECRETASE SUBUNIT APH-1A, ...
Authors:Bai, X.C., Rajendra, E., Yang, G.H., Shi, Y.G., Scheres, S.H.W.
Deposit date:2015-11-10
Release date:2015-12-16
Last modified:2016-12-21
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Sampling the conformational space of the catalytic subunit of human gamma-secretase.
Elife, 4, 2015
5FN4
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CRYO-EM STRUCTURE OF GAMMA SECRETASE IN CLASS 2 OF THE APO- STATE ENSEMBLE
Descriptor:NICASTRIN, PRESENILIN-1, GAMMA-SECRETASE SUBUNIT APH-1A, ...
Authors:Bai, X.C., Rajendra, E., Yang, G.H., Shi, Y.G., Scheres, S.H.W.
Deposit date:2015-11-10
Release date:2015-12-16
Last modified:2016-12-21
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Sampling the conformational space of the catalytic subunit of human gamma-secretase.
Elife, 4, 2015
5FN5
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CRYO-EM STRUCTURE OF GAMMA SECRETASE IN CLASS 3 OF THE APO- STATE ENSEMBLE
Descriptor:NICASTRIN, PRESENILIN-1, GAMMA-SECRETASE SUBUNIT APH-1A, ...
Authors:Bai, X.C., Rajendra, E., Yang, G.H., Shi, Y.G., Scheres, S.H.W.
Deposit date:2015-11-10
Release date:2015-12-16
Last modified:2016-12-21
Method:ELECTRON MICROSCOPY (4.3 Å)
Cite:Sampling the conformational space of the catalytic subunit of human gamma-secretase.
Elife, 4, 2015
5GAP
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BODY REGION OF THE U4/U6.U5 TRI-SNRNP
Descriptor:U4 snRNA, 5' region, nucleotides 1-67, ...
Authors:Nguyen, T.H.D., Galej, W.P., Oubridge, C., Bai, X.C., Newman, A., Scheres, S., Nagai, K.
Deposit date:2015-12-15
Release date:2016-01-27
Last modified:2017-08-30
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Cryo-EM structure of the yeast U4/U6.U5 tri-snRNP at 3.7 angstrom resolution.
Nature, 530, 2016
5M1S
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CRYO-EM STRUCTURE OF THE E. COLI REPLICATIVE DNA POLYMERASE-CLAMP-EXONUCLASE-THETA COMPLEX BOUND TO DNA IN THE EDITING MODE
Descriptor:DNA polymerase III subunit alpha, DNA polymerase III subunit beta, DNA polymerase III subunit epsilon, ...
Authors:Fernandez-Leiro, R., Conrad, J., Scheres, S.H.W., Lamers, M.H.
Deposit date:2016-10-10
Release date:2017-01-18
Last modified:2018-10-24
Method:ELECTRON MICROSCOPY (6.7 Å)
Cite:Self-correcting mismatches during high-fidelity DNA replication.
Nat. Struct. Mol. Biol., 24, 2017
5MZ6
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CRYO-EM STRUCTURE OF A SEPARASE-SECURIN COMPLEX FROM CAENORHABDITIS ELEGANS AT 3.8 A RESOLUTION
Descriptor:SEParase, Interactor of FizzY protein
Authors:Boland, A., Martin, T.G., Zhang, Z., Yang, J., Bai, X.C., Chang, L., Scheres, S.H.W., Barford, D.
Deposit date:2017-01-31
Release date:2017-03-08
Last modified:2017-08-30
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Cryo-EM structure of a metazoan separase-securin complex at near-atomic resolution.
Nat. Struct. Mol. Biol., 24, 2017
5UMD
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STRUCTURE OF THE PLASMODIUM FALCIPARUM 80S RIBOSOME BOUND TO THE ANTIMALARIAL DRUG MEFLOQUINE
Descriptor:28S ribosomal RNA, 5S ribosomal RNA, 5.8S ribosomal RNA, ...
Authors:Wong, W., Bai, X.-C., Brown, A., Scheres, S., Baum, J.
Deposit date:2017-01-27
Release date:2017-03-01
Last modified:2018-10-17
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Mefloquine targets the Plasmodium falciparum 80S ribosome to inhibit protein synthesis.
Nat Microbiol, 2, 2017
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