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5I08
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PREFUSION STRUCTURE OF A HUMAN CORONAVIRUS SPIKE PROTEIN
Descriptor:Spike glycoprotein, envelope glycoprotein chimera
Authors:Kirchdoerfer, R.N., Cottrell, C.A., Wang, N., Pallesen, J., Yassine, H.M., Turner, H.L., Corbett, K.S., Graham, B.S., McLellan, J.S., Ward, A.B.
Deposit date:2016-02-03
Release date:2016-03-02
Last modified:2016-04-13
Method:ELECTRON MICROSCOPY (4.04 Å)
Cite:Pre-fusion structure of a human coronavirus spike protein.
Nature, 531, 2016
5KEL
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EBOV GP IN COMPLEX WITH VARIABLE FAB DOMAINS OF IGGS C2G4 AND C13C6
Descriptor:Ebola surface glycoprotein, GP1, GP2, ...
Authors:Pallesen, J., Murin, C.D., de Val, N., Cottrell, C.A., Hastie, K.M., Turner, H.L., Fusco, M.L., Flyak, A.I., Zeitlin, L., Crowe Jr., J.E., Andersen, K.G., Saphire, E.O., Ward, A.B.
Deposit date:2016-06-09
Release date:2016-09-07
Last modified:2019-12-11
Method:ELECTRON MICROSCOPY (4.3 Å)
Cite:Structures of Ebola virus GP and sGP in complex with therapeutic antibodies.
Nat Microbiol, 1, 2016
5KEM
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EBOV SGP IN COMPLEX WITH VARIABLE FAB DOMAINS OF IGGS C13C6 AND BDBV91
Descriptor:BDBV91 variable Fab domain light chain, BDBV91 variable Fab domain heavy chain, c13C6 variable Fab domain heavy chain, ...
Authors:Pallesen, J., Murin, C.D., de Val, N., Cottrell, C.A., Hastie, K.M., Turner, H.L., Fusco, M.L., Flyak, A.I., Zeitlin, L., Crowe Jr., J.E., Andersen, K.G., Saphire, E.O., Ward, A.B.
Deposit date:2016-06-09
Release date:2016-09-07
Last modified:2019-12-11
Method:ELECTRON MICROSCOPY (5.5 Å)
Cite:Structures of Ebola virus GP and sGP in complex with therapeutic antibodies.
Nat Microbiol, 1, 2016
5KEN
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EBOV GP IN COMPLEX WITH VARIABLE FAB DOMAINS OF IGGS C4G7 AND C13C6
Descriptor:Ebola surface glycoprotein, GP1, GP2, ...
Authors:Pallesen, J., Murin, C.D., de Val, N., Cottrell, C.A., Hastie, K.M., Turner, H.L., Fusco, M.L., Flyak, A.I., Zeitlin, L., Crowe Jr., J.E., Andersen, K.G., Saphire, E.O., Ward, A.B.
Deposit date:2016-06-09
Release date:2016-09-07
Last modified:2019-12-11
Method:ELECTRON MICROSCOPY (4.3 Å)
Cite:Structures of Ebola virus GP and sGP in complex with therapeutic antibodies.
Nat Microbiol, 1, 2016
5VN3
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CRYO-EM MODEL OF B41 SOSIP.664 IN COMPLEX WITH SOLUBLE CD4 (D1-D2) AND FRAGMENT ANTIGEN BINDING VARIABLE DOMAIN OF 17B
Descriptor:17b Fab light chain, Envelope glycoprotein gp160, T-cell surface glycoprotein CD4, ...
Authors:Ozorowski, G., Pallesen, J., Ward, A.B.
Deposit date:2017-04-28
Release date:2017-07-12
Last modified:2019-12-11
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Open and closed structures reveal allostery and pliability in the HIV-1 envelope spike.
Nature, 547, 2017
5VN8
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CRYO-EM MODEL OF B41 SOSIP.664 IN COMPLEX WITH FRAGMENT ANTIGEN BINDING VARIABLE DOMAIN OF B12
Descriptor:Envelope glycoprotein gp160, b12 Fab heavy chain, b12 Fab light chain, ...
Authors:Ozorowski, G., Pallesen, J., Ward, A.B., Cottrell, C.A.
Deposit date:2017-04-28
Release date:2017-07-12
Last modified:2019-12-11
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Open and closed structures reveal allostery and pliability in the HIV-1 envelope spike.
Nature, 547, 2017
5VYH
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CRYSTAL STRUCTURE OF MERS-COV S1 N-TERMINAL DOMAIN
Descriptor:S protein, N-ACETYL-D-GLUCOSAMINE, FOLIC ACID, ...
Authors:Wang, N., Wrapp, D., Pallesen, J., Ward, A.B., McLellan, J.S.
Deposit date:2017-05-25
Release date:2017-08-30
Last modified:2019-12-11
Method:X-RAY DIFFRACTION (2 Å)
Cite:Immunogenicity and structures of a rationally designed prefusion MERS-CoV spike antigen.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5VZR
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CRYSTAL STRUCTURE OF MERS-COV NEUTRALIZING ANTIBODY G4 FAB
Descriptor:G4 antibody heavy chain, G4 antibody light chain, GLYCEROL
Authors:Wang, N., Wrapp, D., McLellan, J.S.
Deposit date:2017-05-29
Release date:2017-08-30
Last modified:2019-12-11
Method:X-RAY DIFFRACTION (1.57 Å)
Cite:Immunogenicity and structures of a rationally designed prefusion MERS-CoV spike antigen.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5W9H
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MERS S ECTODOMAIN TRIMER IN COMPLEX WITH VARIABLE DOMAIN OF NEUTRALIZING ANTIBODY G4
Descriptor:MERS S, G4 VH, G4 VL, ...
Authors:Pallesen, J., Ward, A.B.
Deposit date:2017-06-23
Release date:2017-08-16
Last modified:2019-12-11
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Immunogenicity and structures of a rationally designed prefusion MERS-CoV spike antigen.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5W9I
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MERS S ECTODOMAIN TRIMER IN COMPLEX WITH VARIABLE DOMAIN OF NEUTRALIZING ANTIBODY G4
Descriptor:Spike glycoprotein, G4 VH, G4 VL, ...
Authors:Pallesen, J., Ward, A.B.
Deposit date:2017-06-23
Release date:2017-08-16
Last modified:2019-12-11
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Immunogenicity and structures of a rationally designed prefusion MERS-CoV spike antigen.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5W9J
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MERS S ECTODOMAIN TRIMER IN COMPLEX WITH VARIABLE DOMAIN OF NEUTRALIZING ANTIBODY G4
Descriptor:Spike glycoprotein, G4 VH, G4 VL
Authors:Pallesen, J., Ward, A.B.
Deposit date:2017-06-23
Release date:2017-08-16
Last modified:2019-12-11
Method:ELECTRON MICROSCOPY (4.8 Å)
Cite:Immunogenicity and structures of a rationally designed prefusion MERS-CoV spike antigen.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5W9K
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MERS S ECTODOMAIN TRIMER IN COMPLEX WITH VARIABLE DOMAIN OF NEUTRALIZING ANTIBODY G4
Descriptor:Spike glycoprotein, G4 VH, G4 VL
Authors:Pallesen, J., Ward, A.B.
Deposit date:2017-06-23
Release date:2017-08-16
Last modified:2019-12-11
Method:ELECTRON MICROSCOPY (4.6 Å)
Cite:Immunogenicity and structures of a rationally designed prefusion MERS-CoV spike antigen.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5W9L
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MERS S ECTODOMAIN TRIMER IN COMPLEX WITH VARIABLE DOMAIN OF NEUTRALIZING ANTIBODY G4
Descriptor:Spike glycoprotein, G4 VH, G4 VL
Authors:Pallesen, J., Ward, A.B.
Deposit date:2017-06-23
Release date:2017-08-16
Last modified:2019-12-11
Method:ELECTRON MICROSCOPY (4.8 Å)
Cite:Immunogenicity and structures of a rationally designed prefusion MERS-CoV spike antigen.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5W9M
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MERS S ECTODOMAIN TRIMER IN COMPLEX WITH VARIABLE DOMAIN OF NEUTRALIZING ANTIBODY G4
Descriptor:Spike glycoprotein, G4 VH, G4 VL
Authors:Pallesen, J., Ward, A.B.
Deposit date:2017-06-23
Release date:2017-08-16
Last modified:2019-12-11
Method:ELECTRON MICROSCOPY (4.7 Å)
Cite:Immunogenicity and structures of a rationally designed prefusion MERS-CoV spike antigen.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5W9N
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MERS S ECTODOMAIN TRIMER IN COMPLEX WITH VARIABLE DOMAIN OF NEUTRALIZING ANTIBODY G4
Descriptor:MERS S, G4 VH, G4 VL
Authors:Pallesen, J., Ward, A.B.
Deposit date:2017-06-23
Release date:2017-08-16
Last modified:2019-12-11
Method:ELECTRON MICROSCOPY (5 Å)
Cite:Immunogenicity and structures of a rationally designed prefusion MERS-CoV spike antigen.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5W9O
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MERS S ECTODOMAIN TRIMER IN COMPLEX WITH VARIABLE DOMAIN OF NEUTRALIZING ANTIBODY G4
Descriptor:Spike glycoprotein, G4 VH, G4 VL
Authors:Pallesen, J., Ward, A.B.
Deposit date:2017-06-23
Release date:2017-08-16
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (4.5 Å)
Cite:Immunogenicity and structures of a rationally designed prefusion MERS-CoV spike antigen.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5W9P
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MERS S ECTODOMAIN TRIMER IN COMPLEX WITH VARIABLE DOMAIN OF NEUTRALIZING ANTIBODY G4
Descriptor:Spike glycoprotein, G4 VH, G4 VL
Authors:Pallesen, J., Ward, A.B.
Deposit date:2017-06-23
Release date:2017-08-16
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Immunogenicity and structures of a rationally designed prefusion MERS-CoV spike antigen.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
6AVN
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CRYSTAL STRUCTURE OF UNBOUND ANTI-HIV ANTIBODY FAB PGV19 AT 2.5 A
Descriptor:PGV19 Fab heavy chain, PGV19 Fab light chain, GLYCEROL, ...
Authors:Sarkar, A., Wilson, I.A.
Deposit date:2017-09-03
Release date:2018-06-27
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structure of a cleavage-independent HIV Env recapitulates the glycoprotein architecture of the native cleaved trimer.
Nat Commun, 9, 2018
6B0N
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CRYSTAL STRUCTURE OF THE CLEAVAGE-INDEPENDENT PREFUSION HIV ENV GLYCOPROTEIN TRIMER OF THE CLADE A BG505 ISOLATE (NFL CONSTRUCT) IN COMPLEX WITH FABS PGT122 AND PGV19 AT 3.39 A
Descriptor:PGV19 Fab heavy chain, PGV19 light chain, Envelope glycoprotein gp140, ...
Authors:Sarkar, A., Irimia, A., Wilson, I.A.
Deposit date:2017-09-14
Release date:2018-05-30
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Structure of a cleavage-independent HIV Env recapitulates the glycoprotein architecture of the native cleaved trimer.
Nat Commun, 9, 2018
6CK8
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CRYSTAL STRUCTURE OF ANTI-INFLUENZA SINGLE-DOMAIN LLAMA ANTIBODY SD38
Descriptor:Llama antibody SD38, SULFATE ION, PENTAETHYLENE GLYCOL, ...
Authors:Zhu, X., Wilson, I.A.
Deposit date:2018-02-27
Release date:2018-11-14
Last modified:2019-02-20
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Universal protection against influenza infection by a multidomain antibody to influenza hemagglutinin.
Science, 362, 2018
6CNV
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INFLUENZA B/BRISBANE HEMAGGLUTININ FAB CR9115 SD84H COMPLEX
Descriptor:Hemagglutinin, Envelope glycoprotein, SD84h, ...
Authors:Luo, J., Obmolova, G.
Deposit date:2018-03-09
Release date:2018-11-14
Method:X-RAY DIFFRACTION (4.1 Å)
Cite:Universal protection against influenza infection by a multidomain antibody to influenza hemagglutinin.
Science, 362, 2018
6CNW
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STRUCTURE OF HUMANIZED SINGLE DOMAIN ANTIBODY SD84
Descriptor:humanized antibody SD84h, ACETATE ION, DI(HYDROXYETHYL)ETHER
Authors:Luo, J., Obmolova, O.
Deposit date:2018-03-09
Release date:2018-11-14
Method:X-RAY DIFFRACTION (0.92 Å)
Cite:Universal protection against influenza infection by a multidomain antibody to influenza hemagglutinin.
Science, 362, 2018
6CRQ
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GLUTARALDEHYDE-TREATED BG505 SOSIP.664 ENV IN COMPLEX WITH PGV04 FAB
Descriptor:Envelope glycoprotein gp160, PGV04 VH, PGV04 VL, ...
Authors:Pallesen, J., Ward, A.B.
Deposit date:2018-03-19
Release date:2018-04-18
Last modified:2018-09-19
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Structural and immunologic correlates of chemically stabilized HIV-1 envelope glycoproteins.
PLoS Pathog., 14, 2018
6CRV
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SARS SPIKE GLYCOPROTEIN, STABILIZED VARIANT, C3 SYMMETRY
Descriptor:Spike glycoprotein,Fibritin, N-ACETYL-D-GLUCOSAMINE, BETA-D-MANNOSE
Authors:Kirchdoerfer, R.N., Wang, N., Pallesen, J., Turner, H.L., Cottrell, C.A., McLellan, J.S., Ward, A.B.
Deposit date:2018-03-19
Release date:2018-04-11
Last modified:2019-02-20
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Stabilized coronavirus spikes are resistant to conformational changes induced by receptor recognition or proteolysis.
Sci Rep, 8, 2018
6CRW
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SARS SPIKE GLYCOPROTEIN, STABILIZED VARIANT, SINGLE UPWARDS S1 CTD CONFORMATION
Descriptor:Spike glycoprotein,Fibritin, N-ACETYL-D-GLUCOSAMINE, BETA-D-MANNOSE, ...
Authors:Kirchdoerfer, R.N., Wang, N., Pallesen, J., Turner, H.L., Cottrell, C.A., McLellan, J.S., Ward, A.B.
Deposit date:2018-03-19
Release date:2018-04-11
Last modified:2019-02-20
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Stabilized coronavirus spikes are resistant to conformational changes induced by receptor recognition or proteolysis.
Sci Rep, 8, 2018
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