6CRQ

Glutaraldehyde-treated BG505 SOSIP.664 Env in complex with PGV04 Fab

Summary for 6CRQ

Entry DOI	10.2210/pdb6crq/pdb
EMDB information	7568
Descriptor	Envelope glycoprotein gp160, PGV04 VH, PGV04 VL, ... (9 entities in total)
Functional Keywords	glutaraldehyde, bg505, sosip, pgv04, hiv, hiv-1, trimer, immmune complex, immunogen, env, cross link, b cell activation, th cell activation, viral protein
Biological source	Human immunodeficiency virus 1 More
Total number of polymer chains	12
Total formula weight	378138.03
Authors	Pallesen, J.,Ward, A.B. (deposition date: 2018-03-19, release date: 2018-04-18, Last modification date: 2022-03-16)
Primary citation	Schiffner, T.,Pallesen, J.,Russell, R.A.,Dodd, J.,de Val, N.,LaBranche, C.C.,Montefiori, D.,Tomaras, G.D.,Shen, X.,Harris, S.L.,Moghaddam, A.E.,Kalyuzhniy, O.,Sanders, R.W.,McCoy, L.E.,Moore, J.P.,Ward, A.B.,Sattentau, Q.J. Structural and immunologic correlates of chemically stabilized HIV-1 envelope glycoproteins. PLoS Pathog., 14:e1006986-e1006986, 2018 Cited by PubMed: 29746590 DOI: 10.1371/journal.ppat.1006986 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (4.2 Å)

Structure validation