6CRQ
Glutaraldehyde-treated BG505 SOSIP.664 Env in complex with PGV04 Fab
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, E, I (A, B, F) | Envelope glycoprotein gp160 | polymer | 480 | 53950.2 | 3 | UniProt (Q2N0S5) Pfam (PF00516) | Human immunodeficiency virus 1 | Env polyprotein |
| 2 | B, F, J (C, G, H) | Envelope glycoprotein gp160 | polymer | 153 | 17146.5 | 3 | UniProt (Q2N0S7) Pfam (PF00517) | Human immunodeficiency virus 1 | Env polyprotein |
| 3 | C, G, K (D, I, J) | PGV04 VH | polymer | 228 | 24644.8 | 3 | Homo sapiens | ||
| 4 | D, H, L (E, K, L) | PGV04 VL | polymer | 208 | 23073.8 | 3 | Homo sapiens | ||
| 5 | KA, M, Y (k, M, Y) | alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 748.7 | 3 | In PDB GlyTouCan (G81315DD) | |||
| 6 | BA, CA, DA, FA, GA... (b, c, d, f, g...) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 27 | In PDB GlyTouCan (G42666HT) | |||
| 7 | AA, MA, O (a, m, O) | alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 748.7 | 3 | In PDB GlyTouCan (G22573RC) | |||
| 8 | EA, QA, S (e, q, S) | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 3 | In PDB GlyTouCan (G15407YE) | |||
| 9 | AB, BB, CB, DB, EB... (C, B, G, F, H...) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 18 | Chemie (NAG) |
Sequence modifications
A, B, F: 32 - 508 (UniProt: Q2N0S5)
C, G, H: 512 - 664 (UniProt: Q2N0S7)
| PDB | External Database | Details |
|---|---|---|
| Ala 137 | Asn 136 | conflict |
| Asn 332 | Thr 330 | conflict |
| Cys 501 | Ala 498 | conflict |
| Arg 509 | - | expression tag |
| Arg 510 | - | expression tag |
| Arg 511 | - | expression tag |
| Arg 512 | - | expression tag |
| Arg 513 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Pro 559 | Ile 556 | conflict |
| Cys 605 | Thr 602 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 12 |
| Total formula weight | 356445.7 | |
| Branched | Number of molecules | 36 |
| Total formula weight | 17710.5 | |
| Non-Polymers* | Number of molecules | 18 |
| Total formula weight | 3981.7 | |
| All* | Total formula weight | 378138.0 |
