5KEM

EBOV sGP in complex with variable Fab domains of IgGs c13C6 and BDBV91

Summary for 5KEM

• Entry DOI: 10.2210/pdb5kem/pdb
• Related: 5KEL 5KEN
• EMDB information: 8240 8241 8242
• Descriptor: BDBV91 variable Fab domain light chain, BDBV91 variable Fab domain heavy chain, c13C6 variable Fab domain heavy chain, ... (5 entities in total)
• Functional Keywords: ebola virus secreted glycoprotein, sgp, antibodies, viral protein-immune system complex, viral protein/immune system
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 10
• Total formula weight: 151671.21

Authors

Pallesen, J.,Murin, C.D.,de Val, N.,Cottrell, C.A.,Hastie, K.M.,Turner, H.L.,Fusco, M.L.,Flyak, A.I.,Zeitlin, L.,Crowe Jr., J.E.,Andersen, K.G.,Saphire, E.O.,Ward, A.B. (deposition date: 2016-06-09, release date: 2016-09-07, Last modification date: 2019-12-11)

• Primary citation: Pallesen, J.,Murin, C.D.,de Val, N.,Cottrell, C.A.,Hastie, K.M.,Turner, H.L.,Fusco, M.L.,Flyak, A.I.,Zeitlin, L.,Crowe, J.E.,Andersen, K.G.,Saphire, E.O.,Ward, A.B.; Structures of Ebola virus GP and sGP in complex with therapeutic antibodies.; Nat Microbiol, 1:16128-16128, 2016; PubMed: 27562261; DOI: 10.1038/nmicrobiol.2016.128

Experimental method

ELECTRON MICROSCOPY (5.5 Å)