5VN3

Cryo-EM model of B41 SOSIP.664 in complex with soluble CD4 (D1-D2) and fragment antigen binding variable domain of 17b

Summary for 5VN3

• Entry DOI: 10.2210/pdb5vn3/pdb
• Related: 5vn8
• EMDB information: 8713 8714 8715 8716 8717
• Descriptor: 17b Fab light chain, alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (11 entities in total)
• Functional Keywords: viral fusion, hiv-1, envelope glycoprotein, cd4 receptor binding, immune system
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 15
• Total formula weight: 456059.35

Authors

Ozorowski, G.,Pallesen, J.,Ward, A.B. (deposition date: 2017-04-28, release date: 2017-07-12, Last modification date: 2020-07-29)

• Primary citation: Ozorowski, G.,Pallesen, J.,de Val, N.,Lyumkis, D.,Cottrell, C.A.,Torres, J.L.,Copps, J.,Stanfield, R.L.,Cupo, A.,Pugach, P.,Moore, J.P.,Wilson, I.A.,Ward, A.B.; Open and closed structures reveal allostery and pliability in the HIV-1 envelope spike.; Nature, 547:360-363, 2017; PubMed: 28700571; DOI: 10.1038/nature23010

Experimental method

ELECTRON MICROSCOPY (3.7 Å)