6CS2

SARS Spike Glycoprotein - human ACE2 complex, Stabilized variant, all ACE2-bound particles

Summary for 6CS2

EMDB information7582
DescriptorSpike glycoprotein,Fibritin, Angiotensin-converting enzyme 2, N-ACETYL-D-GLUCOSAMINE, ... (5 entities in total)
Functional Keywordsmembrane fusion, glycoprotein, receptor binding, viral protein, viral protein-hydrolase complex, viral protein/hydrolase
Biological sourceHuman SARS coronavirus (SARS-CoV)
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Total number of polymer chains4
Total molecular weight493102.78
Authors
Kirchdoerfer, R.N.,Wang, N.,Pallesen, J.,Turner, H.L.,Cottrell, C.A.,McLellan, J.S.,Ward, A.B. (deposition date: 2018-03-19, release date: 2018-04-11, Last modification date: 2019-02-20)
Primary citation
Kirchdoerfer, R.N.,Wang, N.,Pallesen, J.,Wrapp, D.,Turner, H.L.,Cottrell, C.A.,Corbett, K.S.,Graham, B.S.,McLellan, J.S.,Ward, A.B.
Stabilized coronavirus spikes are resistant to conformational changes induced by receptor recognition or proteolysis.
Sci Rep, 8:15701-15701, 2018
PubMed: 30356097 (PDB entries with the same primary citation)
DOI: 10.1038/s41598-018-34171-7
MImport into Mendeley
Experimental method
ELECTRON MICROSCOPY
?

Structure validation

ClashscoreRamachandran outliersSidechain outliers8 0.1% 0.2%MetricValuePercentile RanksWorseBetterPercentile relative to all structuresPercentile relative to all EM structures