5W9L

MERS S ectodomain trimer in complex with variable domain of neutralizing antibody G4

Summary for 5W9L

EMDB information8787 8793 8783 8784 8785 8786 8788 8789 8790 8791 8792
DescriptorSpike glycoprotein, G4 VH, G4 VL (3 entities in total)
Functional Keywordsimmunogen, peplomer, viral spike, mers, mers s protein, antibody, g4, viral protein
Biological sourceMiddle East respiratory syndrome-related coronavirus
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Total number of polymer chains10
Total molecular weight976315.25
Authors
Pallesen, J.,Ward, A.B. (deposition date: 2017-06-23, release date: 2017-08-16, Last modification date: 2019-12-11)
Primary citation
Pallesen, J.,Wang, N.,Corbett, K.S.,Wrapp, D.,Kirchdoerfer, R.N.,Turner, H.L.,Cottrell, C.A.,Becker, M.M.,Wang, L.,Shi, W.,Kong, W.P.,Andres, E.L.,Kettenbach, A.N.,Denison, M.R.,Chappell, J.D.,Graham, B.S.,Ward, A.B.,McLellan, J.S.
Immunogenicity and structures of a rationally designed prefusion MERS-CoV spike antigen.
Proc. Natl. Acad. Sci. U.S.A., 114:E7348-E7357, 2017
PubMed: 28807998 (PDB entries with the same primary citation)
DOI: 10.1073/pnas.1707304114
MImport into Mendeley
Experimental method
ELECTRON MICROSCOPY
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Structure validation

ClashscoreRamachandran outliersSidechain outliers4 0.9% 0.1%MetricValuePercentile RanksWorseBetterPercentile relative to all structuresPercentile relative to all EM structures
Download full validation report