Author results

1GUW
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STRUCTURE OF THE CHROMODOMAIN FROM MOUSE HP1BETA IN COMPLEX WITH THE LYSINE 9-METHYL HISTONE H3 N-TERMINAL PEPTIDE, NMR, 25 STRUCTURES
Descriptor:CHROMOBOX PROTEIN HOMOLOG 1, HISTONE H3.1
Authors:Nielsen, P.R., Nietlispach, D., Mott, H.R., Callaghan, J.M., Bannister, A., Kouzarides, T., Murzin, A.G., Murzina, N.V., Laue, E.D.
Deposit date:2002-02-01
Release date:2002-03-12
Last modified:2018-01-17
Method:SOLUTION NMR
Cite:Structure of the Hp1 Chromodomain Bound to Histone H3 Methylated at Lysine 9
Nature, 416, 2002
1AP0
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STRUCTURE OF THE CHROMATIN BINDING (CHROMO) DOMAIN FROM MOUSE MODIFIER PROTEIN 1, NMR, 26 STRUCTURES
Descriptor:MODIFIER PROTEIN 1
Authors:Ball, L.J., Murzina, N.V., Broadhurst, R.W., Raine, A.R.C., Archer, S.J., Stott, F.J., Murzin, A.G., Singh, P.B., Domaille, P.J., Laue, E.D.
Deposit date:1997-07-22
Release date:1998-07-22
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structure of the chromatin binding (chromo) domain from mouse modifier protein 1.
EMBO J., 16, 1997
1OI1
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CRYSTAL STRUCTURE OF THE MBT DOMAINS OF HUMAN SCML2
Descriptor:SCML2 PROTEIN, DI(HYDROXYETHYL)ETHER
Authors:Sathyamurthy, A., Allen, M.D., Murzin, A.G., Bycroft, M.
Deposit date:2003-06-04
Release date:2003-06-15
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (1.78 Å)
Cite:Crystal Structure of the Malignant Brain Tumor (Mbt) Repeats in Sex Comb on Midleg-Like 2 (Scml2).
J.Biol.Chem., 278, 2003
1Z0R
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SOLUTION STRUCTURE OF THE N-TERMINAL DNA RECOGNITION DOMAIN OF THE BACILLUS SUBTILIS TRANSCRIPTION-STATE REGULATOR ABRB
Descriptor:Transition state regulatory protein abrB
Authors:Bobay, B.G., Andreeva, A., Mueller, G.A., Cavanagh, J., Murzin, A.G.
Deposit date:2005-03-02
Release date:2005-03-15
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Revised structure of the AbrB N-terminal domain unifies a diverse superfamily of putative DNA-binding proteins.
Febs Lett., 579, 2005
2BUD
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THE SOLUTION STRUCTURE OF THE CHROMO BARREL DOMAIN FROM THE MALES- ABSENT ON THE FIRST (MOF) PROTEIN
Descriptor:MALES-ABSENT ON THE FIRST PROTEIN
Authors:Nielsen, P.R., Nietlispach, D., Buscaino, A., Warner, R.J., Akhtar, A., Murzin, A.G., Murzina, N.V., Laue, E.D.
Deposit date:2005-06-09
Release date:2005-06-24
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structure of the Chromo Barrel Domain from the Mof Acetyltransferase
J.Biol.Chem., 280, 2005
2W6K
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THE CRYSTAL STRUCTURE AT 1.7 A RESOLUTION OF COBE, A PROTEIN FROM THE COBALAMIN (VITAMIN B12) BIOSYNTHETIC PATHWAY
Descriptor:COBE, SULFATE ION, GLYCEROL
Authors:Vevodova, J., Smith, D., McGoldrick, H., Deery, E., Murzin, A.G., Warren, M.J., Wilson, K.S.
Deposit date:2008-12-18
Release date:2008-12-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:The Crystal Structure at 1.7 A Resolution of Cobe, a Protein from the Cobalamin (Vitamin B12) Biosynthetic Pathway
To be Published
2W6L
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THE CRYSTAL STRUCTURE AT 1.7 A RESOLUTION OF COBE, A PROTEIN FROM THE COBALAMIN (VITAMIN B12) BIOSYNTHETIC PATHWAY
Descriptor:COBE, SULFATE ION, GLYCEROL
Authors:Vevodova, J., Smith, D., McGoldrick, H., Deery, E., Murzin, A.G., Warren, M.J., Wilson, K.S.
Deposit date:2008-12-18
Release date:2008-12-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.89 Å)
Cite:The Crystal Structure at 1.7 A Resolution of Cobe, a Protein from the Cobalamin (Vitamin B12) Biosynthetic Pathway
To be Published
5O3L
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PAIRED HELICAL FILAMENT IN ALZHEIMER'S DISEASE BRAIN
Descriptor:Microtubule-associated protein tau
Authors:Fitzpatrick, A.W.P., Falcon, B., He, S., Murzin, A.G., Murshudov, G., Garringer, H.G., Crowther, R.A., Ghetti, B., Goedert, M., Scheres, S.H.W.
Deposit date:2017-05-24
Release date:2017-07-26
Last modified:2018-03-28
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Cryo-EM structures of tau filaments from Alzheimer's disease.
Nature, 547, 2017
5O3O
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PRONASE-TREATED PAIRED HELICAL FILAMENT IN ALZHEIMER'S DISEASE BRAIN
Descriptor:Microtubule-associated protein tau
Authors:Fitzpatrick, A.W.P., Falcon, B., He, S., Murzin, A.G., Murshudov, G., Garringer, H.G., Crowther, R.A., Ghetti, B., Goedert, M., Scheres, S.H.W.
Deposit date:2017-05-24
Release date:2017-07-26
Last modified:2017-08-02
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Cryo-EM structures of tau filaments from Alzheimer's disease.
Nature, 547, 2017
5O3T
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STRAIGHT FILAMENT IN ALZHEIMER'S DISEASE BRAIN
Descriptor:Microtubule-associated protein tau
Authors:Fitzpatrick, A.W.P., Falcon, B., He, S., Murzin, A.G., Murshudov, G., Garringer, H.G., Crowther, R.A., Ghetti, B., Goedert, M., Scheres, S.H.W.
Deposit date:2017-05-24
Release date:2017-07-26
Last modified:2017-08-02
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Cryo-EM structures of tau filaments from Alzheimer's disease.
Nature, 547, 2017
6GX5
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NARROW PICK FILAMENT FROM PICK'S DISEASE BRAIN
Descriptor:Microtubule-associated protein tau
Authors:Falcon, B., Zhang, W., Murzin, A.G., Murshudov, G., Garringer, H.J., Vidal, R., Crowther, R.A., Ghetti, B., Scheres, S.H.W., Goedert, M.
Deposit date:2018-06-26
Release date:2018-09-12
Last modified:2018-09-19
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Structures of filaments from Pick's disease reveal a novel tau protein fold.
Nature, 561, 2018
6HRE
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PAIRED HELICAL FILAMENT FROM SPORADIC ALZHEIMER'S DISEASE BRAIN
Descriptor:Microtubule-associated protein tau
Authors:Falcon, B., Zhang, W., Schweighauser, M., Murzin, A.G., Vidal, R., Garringer, H.J., Ghetti, B., Scheres, S.H.W., Goedert, M.
Deposit date:2018-09-26
Release date:2018-10-10
Last modified:2018-11-07
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Tau filaments from multiple cases of sporadic and inherited Alzheimer's disease adopt a common fold.
Acta Neuropathol., 136, 2018
6HRF
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STRAIGHT FILAMENT FROM SPORADIC ALZHEIMER'S DISEASE BRAIN
Descriptor:Microtubule-associated protein tau
Authors:Falcon, B., Zhang, W., Schweighauser, M., Murzin, A.G., Vidal, R., Garringer, H.J., Ghetti, B., Scheres, S.H.W., Goedert, M.
Deposit date:2018-09-26
Release date:2018-10-10
Last modified:2018-11-07
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Tau filaments from multiple cases of sporadic and inherited Alzheimer's disease adopt a common fold.
Acta Neuropathol., 136, 2018
6QJH
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CRYO-EM STRUCTURE OF HEPARIN-INDUCED 2N4R TAU SNAKE FILAMENTS
Descriptor:Microtubule-associated protein tau
Authors:Zhang, W., Falcon, B., Murzin, A.G., Fan, J., Crowther, R.A., Goedert, M., Scheres, S.H.W.
Deposit date:2019-01-24
Release date:2019-02-20
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Heparin-induced tau filaments are polymorphic and differ from those in Alzheimer's and Pick's diseases.
Elife, 8, 2019
6QJM
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CRYO-EM STRUCTURE OF HEPARIN-INDUCED 2N4R TAU TWISTER FILAMENTS
Descriptor:Microtubule-associated protein tau
Authors:Zhang, W., Falcon, B., Murzin, A.G., Fan, J., Crowther, R.A., Goedert, M., Scheres, S.H.W.
Deposit date:2019-01-24
Release date:2019-02-27
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Heparin-induced tau filaments are polymorphic and differ from those in Alzheimer's and Pick's diseases.
Elife, 8, 2019
6QJP
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CRYO-EM STRUCTURE OF HEPARIN-INDUCED 2N4R TAU JAGGED FILAMENTS
Descriptor:Microtubule-associated protein tau
Authors:Zhang, W., Falcon, B., Murzin, A.G., Fan, J., Crowther, R.A., Goedert, M., Scheres, S.H.W.
Deposit date:2019-01-24
Release date:2019-02-20
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Heparin-induced tau filaments are polymorphic and differ from those in Alzheimer's and Pick's diseases.
Elife, 8, 2019
6QJQ
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CRYO-EM STRUCTURE OF HEPARIN-INDUCED 2N3R TAU FILAMENTS
Descriptor:Microtubule-associated protein tau
Authors:Zhang, W., Falcon, B., Murzin, A.G., Fan, J., Crowther, R.A., Goedert, M., Scheres, S.H.W.
Deposit date:2019-01-24
Release date:2019-02-20
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Heparin-induced tau filaments are polymorphic and differ from those in Alzheimer's and Pick's diseases.
Elife, 8, 2019
1JOG
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STRUCTURE OF HI0074 FROM HEAMOPHILUS INFLUENZAE REVEALS THE FOLD OF A SUBSTRATE BINDING DOMAIN OF A NUCLEOTIDYLTRANSFERASE
Descriptor:HYPOTHETICAL PROTEIN HI0074
Authors:Lehmann, C., Lim, K., Herzberg, O., Structure 2 Function Project (S2F)
Deposit date:2001-07-29
Release date:2002-12-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The HI0073/HI0074 protein pair from Haemophilus influenzae is a member of a new nucleotidyltransferase family: Structure, sequence analyses, and solution studies
Proteins, 50, 2003
1NQB
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TRIVALENT ANTIBODY FRAGMENT
Descriptor:SINGLE-CHAIN ANTIBODY FRAGMENT
Authors:Williams, R.L., Pei, X.Y.
Deposit date:1997-04-04
Release date:1997-08-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:The 2.0-A resolution crystal structure of a trimeric antibody fragment with noncognate VH-VL domain pairs shows a rearrangement of VH CDR3.
Proc.Natl.Acad.Sci.USA, 94, 1997
1PVM
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CRYSTAL STRUCTURE OF A CONSERVED CBS DOMAIN PROTEIN TA0289 OF UNKNOWN FUNCTION FROM THERMOPLASMA ACIDOPHILUM
Descriptor:conserved hypothetical protein Ta0289, MERCURY (II) ION
Authors:Zhang, R., Joachimiak, A., Edwards, A., Savchenko, A., Xu, L., Midwest Center for Structural Genomics (MCSG)
Deposit date:2003-06-27
Release date:2004-01-20
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Biochemical and structural characterization of a novel family of cystathionine beta-synthase domain proteins fused to a Zn ribbon-like domain
J.Mol.Biol., 375, 2008
1SRO
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S1 RNA BINDING DOMAIN, NMR, 20 STRUCTURES
Descriptor:PNPASE
Authors:Bycroft, M.
Deposit date:1996-11-27
Release date:1997-04-01
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:The solution structure of the S1 RNA binding domain: a member of an ancient nucleic acid-binding fold.
Cell(Cambridge,Mass.), 88, 1997
1STU
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DOUBLE STRANDED RNA BINDING DOMAIN
Descriptor:MATERNAL EFFECT PROTEIN STAUFEN
Authors:Bycroft, M.
Deposit date:1995-05-16
Release date:1995-07-31
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:NMR solution structure of a dsRNA binding domain from Drosophila staufen protein reveals homology to the N-terminal domain of ribosomal protein S5.
EMBO J., 14, 1995
2FY9
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SOLUTION STRUCTURE OF THE N-TERMINAL DNA RECOGNITION DOMAIN OF THE BACILLUS SUBTILIS TRANSCRIPTION-STATE REGULATOR ABH
Descriptor:Putative transition state regulator abh
Authors:Cavanagh, J., Bobay, B.G.
Deposit date:2006-02-07
Release date:2006-05-23
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:NMR Structure of AbhN and Comparison with AbrBN: First insights into the DNA-binding promiscuity and specificity of AbrB-like transition-state regulator proteins
J.Biol.Chem., 281, 2006
2P5X
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CRYSTAL STRUCTURE OF MAF DOMAIN OF HUMAN N-ACETYLSEROTONIN O-METHYLTRANSFERASE-LIKE PROTEIN
Descriptor:N-acetylserotonin O-methyltransferase-like protein, PHOSPHATE ION
Authors:Min, J., Wu, H., Dombrovski, L., Loppnau, P., Weigelt, J., Sundstrom, M., Arrowsmith, C.H., Edwards, A.M., Bochkarev, A., Plotnikov, A.N., Structural Genomics Consortium (SGC)
Deposit date:2007-03-16
Release date:2007-03-27
Last modified:2014-01-15
Method:X-RAY DIFFRACTION (2 Å)
Cite:Biochemical and structural studies of conserved maf proteins revealed nucleotide pyrophosphatases with a preference for modified nucleotides.
Chem.Biol., 20, 2013
2QH1
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STRUCTURE OF TA289, A CBS-RUBREDOXIN-LIKE PROTEIN, IN ITS FE+2-BOUND STATE
Descriptor:Hypothetical protein Ta0289, FE (II) ION
Authors:Singer, A.U., Proudfoot, M., Brown, G., Xu, L., Savchenko, A., Yakunin, A.F., Midwest Center for Structural Genomics (MCSG)
Deposit date:2007-06-29
Release date:2008-02-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Biochemical and structural characterization of a novel family of cystathionine beta-synthase domain proteins fused to a Zn ribbon-like domain.
J.Mol.Biol., 375, 2008
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