6NWP
Chronic traumatic encephalopathy Type I Tau filament
Summary for 6NWP
Entry DOI | 10.2210/pdb6nwp/pdb |
EMDB information | 0527 |
Descriptor | Microtubule-associated protein tau (2 entities in total) |
Functional Keywords | tau, chronic traumatic encephalopathy, filament, amyloid, protein fibril |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 6 |
Total formula weight | 275519.23 |
Authors | Falcon, B.,Zivanov, J.,Zhang, W.,Murzin, A.G.,Garringer, H.J.,Vidal, R.,Crowther, R.A.,Newell, K.L.,Ghetti, B.,Goedert, M.,Scheres, H.W. (deposition date: 2019-02-07, release date: 2019-03-27, Last modification date: 2024-07-10) |
Primary citation | Falcon, B.,Zivanov, J.,Zhang, W.,Murzin, A.G.,Garringer, H.J.,Vidal, R.,Crowther, R.A.,Newell, K.L.,Ghetti, B.,Goedert, M.,Scheres, S.H.W. Novel tau filament fold in chronic traumatic encephalopathy encloses hydrophobic molecules. Nature, 568:420-423, 2019 Cited by PubMed: 30894745DOI: 10.1038/s41586-019-1026-5 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (2.3 Å) |
Structure validation
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