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7NRV

Paired helical filament from Alzheimer's disease with PET ligand APN-1607

Summary for 7NRV
Entry DOI10.2210/pdb7nrv/pdb
EMDB information12551
DescriptorMicrotubule-associated protein tau (1 entity in total)
Functional Keywordstau filament, protein fibril, positron emission tomography
Biological sourceHomo sapiens (Human)
Total number of polymer chains10
Total formula weight459198.71
Authors
Primary citationShi, Y.,Murzin, A.G.,Falcon, B.,Epstein, A.,Machin, J.,Tempest, P.,Newell, K.L.,Vidal, R.,Garringer, H.J.,Sahara, N.,Higuchi, M.,Ghetti, B.,Jang, M.K.,Scheres, S.H.W.,Goedert, M.
Cryo-EM structures of tau filaments from Alzheimer's disease with PET ligand APN-1607.
Acta Neuropathol, 141:697-708, 2021
Cited by
PubMed: 33723967
DOI: 10.1007/s00401-021-02294-3
PDB entries with the same primary citation
Experimental method
ELECTRON MICROSCOPY (3 Å)
Structure validation

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