6NWQ

Chronic traumatic encephalopathy Type II Tau filament

Summary for 6NWQ

• Entry DOI: 10.2210/pdb6nwq/pdb
• Related: 6NWP
• EMDB information: 0527 0528
• Descriptor: Microtubule-associated protein tau (1 entity in total)
• Functional Keywords: tau, chronic traumatic encephalopathy, filament, amyloid, protein fibril
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 6
• Total formula weight: 275519.23

Authors

Falcon, B.,Zivanov, J.,Zhang, W.,Murzin, A.G.,Garringer, H.J.,Vidal, R.,Crowther, R.A.,Newell, K.L.,Ghetti, B.,Goedert, M.,Scheres, H.W. (deposition date: 2019-02-07, release date: 2019-03-27, Last modification date: 2022-03-30)

• Primary citation: Falcon, B.,Zivanov, J.,Zhang, W.,Murzin, A.G.,Garringer, H.J.,Vidal, R.,Crowther, R.A.,Newell, K.L.,Ghetti, B.,Goedert, M.,Scheres, S.H.W.; Novel tau filament fold in chronic traumatic encephalopathy encloses hydrophobic molecules.; Nature, 568:420-423, 2019; PubMed: 30894745; DOI: 10.1038/s41586-019-1026-5

Experimental method

ELECTRON MICROSCOPY (3.4 Å)