Author results

6ZOW
  • Download 6zow
  • View 6zow
Molmil generated image of 6zow
SARS-COV-2 SPIKE IN PREFUSION STATE
Descriptor:Spike glycoprotein, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Martinez, M., Marabini, R., Carazo, J.M.
Deposit date:2020-07-07
Release date:2020-07-29
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Continuous flexibility analysis of SARS-CoV-2 Spike prefusion structures.
Biorxiv, 2020
6ZP5
  • Download 6zp5
  • View 6zp5
Molmil generated image of 6zp5
SARS-COV-2 SPIKE IN PREFUSION STATE (FLEXIBILITY ANALYSIS, 1-UP CLOSED CONFORMATION)
Descriptor:Spike glycoprotein, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Martinez, M., Marabini, R., Carazo, J.M.
Deposit date:2020-07-08
Release date:2020-07-29
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Continuous flexibility analysis of SARS-CoV-2 Spike prefusion structures.
Biorxiv, 2020
6ZP7
  • Download 6zp7
  • View 6zp7
Molmil generated image of 6zp7
SARS-COV-2 SPIKE IN PREFUSION STATE (FLEXIBILITY ANALYSIS, 1-UP OPEN CONFORMATION)
Descriptor:Spike glycoprotein, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Martinez, M., Marabini, R., Carazo, J.M.
Deposit date:2020-07-08
Release date:2020-07-29
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Continuous flexibility analysis of SARS-CoV-2 Spike prefusion structures.
Biorxiv, 2020
5JD3
  • Download 5jd3
  • View 5jd3
Molmil generated image of 5jd3
CRYSTAL STRUCTURE OF LAE5, AN ALPHA/BETA HYDROLASE ENZYME FROM THE METAGENOME OF LAKE ARREO, SPAIN
Descriptor:LAE5, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ...
Authors:Stogios, P.J., Xu, X., Nocek, B., Cui, H., Yim, V., Martinez-Martinez, M., Alcaide, M., Ferrer, M., Savchenko, A.
Deposit date:2016-04-15
Release date:2016-05-04
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:To be published
To Be Published
5JD4
  • Download 5jd4
  • View 5jd4
Molmil generated image of 5jd4
CRYSTAL STRUCTURE OF LAE6 SER161ALA MUTANT, AN ALPHA/BETA HYDROLASE ENZYME FROM THE METAGENOME OF LAKE ARREO, SPAIN
Descriptor:LAE6, SULFATE ION, GLYCEROL, ...
Authors:Stogios, P.J., Xu, X., Alcaide, M., Yim, V., Cui, H., Martinez-Martinez, M., Ferrer, M., Savchenko, A.
Deposit date:2016-04-15
Release date:2016-05-04
Last modified:2017-04-26
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Crystal structure of LAE6 Ser161Ala mutant, an alpha/beta hydrolase enzyme from the metagenome of Lake Arreo, Spain
To Be Published
5JD5
  • Download 5jd5
  • View 5jd5
Molmil generated image of 5jd5
CRYSTAL STRUCTURE OF MGS-MILE3, AN ALPHA/BETA HYDROLASE ENZYME FROM THE METAGENOME OF PYRENE-PHENANTHRENE ENRICHMENT CULTURE WITH SEDIMENT SAMPLE OF MILAZZO HARBOR, ITALY
Descriptor:MGS-MilE3, CHLORIDE ION
Authors:Stogios, P.J., Xu, X., Cui, H., Martinez-Martinez, M., Chernikova, T.N., Golyshin, P.N., Yakimov, M.M., Ferrer, M., Savchenko, A.
Deposit date:2016-04-15
Release date:2016-05-04
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Crystal structure of MGS-MilE3, an alpha/beta hydrolase enzyme from the metagenome of pyrene-phenanthrene enrichment culture with sediment sample of Milazzo Harbor, Italy
To Be Published
5JD6
  • Download 5jd6
  • View 5jd6
Molmil generated image of 5jd6
CRYSTAL STRUCTURE OF MGS-MCHE2, AN ALPHA/BETA HYDROLASE ENZYME FROM THE METAGENOME OF SEDIMENTS FROM THE LAGOON OF MAR CHICA, MOROCCO
Descriptor:MGS-MChE2
Authors:Stogios, P.J., Xu, X., Nocek, B., Yim, V., Cui, H., Martinez-Martinez, M., Golyshin, P.N., Yakima, M.M., Ferrer, M., Savchenko, A.
Deposit date:2016-04-15
Release date:2016-05-04
Method:X-RAY DIFFRACTION (2.463 Å)
Cite:Crystal structure of MGS-MChE2, an alpha/beta hydrolase enzyme from the metagenome of sediments from the lagoon of Mar Chica, Morocco
To Be Published
3EY6
  • Download 3ey6
  • View 3ey6
Molmil generated image of 3ey6
CRYSTAL STRUCTURE OF THE FK506-BINDING DOMAIN OF HUMAN FKBP38
Descriptor:FK506-binding protein 8
Authors:Parthier, C., Maestre-Martinez, M., Neumann, P., Edlich, F., Fischer, G., Luecke, C., Stubbs, M.T.
Deposit date:2008-10-19
Release date:2009-10-27
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (1.05 Å)
Cite:A charge-sensitive loop in the FKBP38 catalytic domain modulates Bcl-2 binding.
J.Mol.Recognit., 24, 2011
2F2D
  • Download 2f2d
  • View 2f2d
Molmil generated image of 2f2d
SOLUTION STRUCTURE OF THE FK506-BINDING DOMAIN OF HUMAN FKBP38
Descriptor:38 kDa FK-506 binding protein homolog, FKBP38
Authors:Maestre-Martinez, M., Edlich, F., Jarczowski, F., Weiwad, M., Fischer, G., Luecke, C.
Deposit date:2005-11-16
Release date:2006-05-02
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution Structure of the FK506-Binding Domain of Human FKBP38
J.BIOMOL.NMR, 34, 2006
2KDU
  • Download 2kdu
  • View 2kdu
Molmil generated image of 2kdu
STRUCTURAL BASIS OF THE MUNC13-1/CA2+-CALMODULIN INTERACTION: A NOVEL 1-26 CALMODULIN BINDING MOTIF WITH A BIPARTITE BINDING MODE
Descriptor:Calmodulin, Protein unc-13 homolog A, CALCIUM ION
Authors:Rodriguez-Castaneda, F.A., Maestre-Martinez, M., Coudevylle, N., Dimova, K., Jahn, O., Junge, H., Becker, S., Brose, N., Carlomagno, T., Griesinger, C.
Deposit date:2009-01-19
Release date:2009-12-15
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Modular architecture of Munc13/calmodulin complexes: dual regulation by Ca2+ and possible function in short-term synaptic plasticity.
Embo J., 29, 2010
4TR2
  • Download 4tr2
  • View 4tr2
Molmil generated image of 4tr2
CRYSTAL STRUCTURE OF PVSUB1
Descriptor:Subtilisin-like 1 serine protease, CALCIUM ION, PHOSPHATE ION
Authors:Giganti, D., Bouillon, A., Martinez, M., Weber, P., Girard-Blanc, C., Petres, S., Haouz, A., Barale, J.C., Alzari, P.M.
Deposit date:2014-06-13
Release date:2014-09-17
Last modified:2017-08-30
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:A novel Plasmodium-specific prodomain fold regulates the malaria drug target SUB1 subtilase.
Nat Commun, 5, 2014
4Q30
  • Download 4q30
  • View 4q30
Molmil generated image of 4q30
NITROWILLARDIINE BOUND TO THE LIGAND BINDING DOMAIN OF GLUA2 AT PH 3.5
Descriptor:Glutamate receptor 2 CHIMERIC PROTEIN, 3-(5-nitro-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-L-alanine, ZINC ION
Authors:Ahmed, A.H., Oswald, R.E.
Deposit date:2014-04-10
Release date:2014-06-04
Last modified:2017-07-26
Method:X-RAY DIFFRACTION (2.03 Å)
Cite:Thermodynamics and mechanism of the interaction of willardiine partial agonists with a glutamate receptor: implications for drug development.
Biochemistry, 53, 2014
2HDP
  • Download 2hdp
  • View 2hdp
Molmil generated image of 2hdp
SOLUTION STRUCTURE OF HDM2 RING FINGER DOMAIN
Descriptor:Ubiquitin-protein ligase E3 Mdm2, ZINC ION
Authors:Kostic, M., Matt, T., Yamout-Martinez, M., Dyson, H.J., Wright, P.E.
Deposit date:2006-06-20
Release date:2006-11-21
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structure of the Hdm2 C2H2C4 RING, a domain critical for ubiquitination of p53.
J.Mol.Biol., 363, 2006
6I8F
  • Download 6i8f
  • View 6i8f
Molmil generated image of 6i8f
STRUCTURE OF ESTER-HYDROLASE EH1AB1 FROM THE METAGENOME OF LAKE ARREO
Descriptor:EH1AB1, DI(HYDROXYETHYL)ETHER, GLYCEROL, ...
Authors:Cea-Rama, I., Sanz-Aparicio, J.
Deposit date:2018-11-20
Release date:2019-11-27
Last modified:2020-01-15
Method:X-RAY DIFFRACTION (2.11 Å)
Cite:Genetically engineered proteins with two active sites for enhanced biocatalysis and synergistic chemo- and biocatalysis
Nat Catal, 2019
6RB0
  • Download 6rb0
  • View 6rb0
Molmil generated image of 6rb0
STRUCTURE OF ESTER-HYDROLASE EH1AB1 FROM THE METAGENOME OF LAKE ARREO COMPLEXED WITH A DERIVATIVE OF METHYL 4-NITROPHENYL HEXYLPHOSPHONATE
Descriptor:EH1AB1, GLYCEROL, methyl hydrogen (R)-hexylphosphonate
Authors:Cea-Rama, I., Sanz-Aparicio, J.
Deposit date:2019-04-08
Release date:2019-12-25
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Genetically engineered proteins with two active sites for enhanced biocatalysis and synergistic chemo- and biocatalysis
Nat Catal, 2019
6RKY
  • Download 6rky
  • View 6rky
Molmil generated image of 6rky
STRUCTURE OF ESTER-HYDROLASE EH1AB1 FROM THE METAGENOME OF LAKE ARREO COMPLEXED WITH A DERIVATIVE OF BIPYRIDINE PHOSPHONATE
Descriptor:EH1AB1, GLYCEROL, DI(HYDROXYETHYL)ETHER
Authors:Cea-Rama, I., Sanz-Aparicio, J.
Deposit date:2019-04-30
Release date:2019-12-25
Method:X-RAY DIFFRACTION (2.79 Å)
Cite:Genetically engineered proteins with two active sites for enhanced biocatalysis and synergistic chemo- and biocatalysis
Nat Catal, 2019
4QXM
  • Download 4qxm
  • View 4qxm
Molmil generated image of 4qxm
CRYSTAL STRUCTURE OF THE INHA:GSK_SB713 COMPLEX
Descriptor:Enoyl-[acyl-carrier-protein] reductase [NADH], NICOTINAMIDE-ADENINE-DINUCLEOTIDE, N-(2-chloro-4-fluorobenzyl)-4-[(3,5-dimethyl-1H-pyrazol-1-yl)methyl]benzamide
Authors:Gulten, G., Sacchettini, J.C.
Deposit date:2014-07-21
Release date:2015-07-22
Last modified:2016-04-27
Method:X-RAY DIFFRACTION (2.196 Å)
Cite:N-Benzyl-4-((heteroaryl)methyl)benzamides: A New Class of Direct NADH-Dependent 2-trans Enoyl-Acyl Carrier Protein Reductase (InhA) Inhibitors with Antitubercular Activity.
Chemmedchem, 11, 2016
5NCR
  • Download 5ncr
  • View 5ncr
Molmil generated image of 5ncr
OH1 FROM THE ORF VIRUS: A TYROSINE PHOSPHATASE THAT DISPLAYS DISTINCT STRUCTURAL FEATURES AND TRIPLE SUBSTRATE SPECIFICITY
Descriptor:tyrosine phosphatase, PHOSPHATE ION, SULFATE ION
Authors:Segovia, D., Haouz, A., Berois, M., Villarino, A., Andre-Leroux, G.
Deposit date:2017-03-06
Release date:2017-08-09
Last modified:2019-10-16
Method:X-RAY DIFFRACTION (1.89 Å)
Cite:OH1 from Orf Virus: A New Tyrosine Phosphatase that Displays Distinct Structural Features and Triple Substrate Specificity.
J. Mol. Biol., 429, 2017
5V3R
  • Download 5v3r
  • View 5v3r
Molmil generated image of 5v3r
CHMP4C IN COMPLEX WITH ALIX BRO1
Descriptor:Programmed cell death 6-interacting protein, Charged multivesicular body protein 4c
Authors:Wenzel, D.M., Alam, S.L., Sundquist, W.I.
Deposit date:2017-03-08
Release date:2018-09-12
Last modified:2018-10-03
Method:X-RAY DIFFRACTION (1.906 Å)
Cite:A cancer-associated polymorphism in ESCRT-III disrupts the abscission checkpoint and promotes genome instability.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
5WA1
  • Download 5wa1
  • View 5wa1
Molmil generated image of 5wa1
CHMP4C A232T IN COMPLEX WITH ALIX BRO1
Descriptor:Programmed cell death 6-interacting protein, Charged multivesicular body protein 4c
Authors:Wenzel, D.M., Alam, S.L., Sundquist, W.I.
Deposit date:2017-06-24
Release date:2018-09-19
Last modified:2020-01-01
Method:X-RAY DIFFRACTION (1.868 Å)
Cite:A cancer-associated polymorphism in ESCRT-III disrupts the abscission checkpoint and promotes genome instability.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
167327
PDB entries from 2020-08-05