4TR2
Crystal structure of PvSUB1
Summary for 4TR2
Entry DOI | 10.2210/pdb4tr2/pdb |
Descriptor | Subtilisin-like 1 serine protease, CALCIUM ION, PHOSPHATE ION, ... (4 entities in total) |
Functional Keywords | plasmodium egress protease; hydrolase; calcium-binding, hydrolase |
Biological source | Plasmodium vivax |
Total number of polymer chains | 2 |
Total formula weight | 147876.28 |
Authors | Giganti, D.,Bouillon, A.,Martinez, M.,Weber, P.,Girard-Blanc, C.,Petres, S.,Haouz, A.,Barale, J.C.,Alzari, P.M. (deposition date: 2014-06-13, release date: 2014-09-17, Last modification date: 2023-12-20) |
Primary citation | Giganti, D.,Bouillon, A.,Tawk, L.,Robert, F.,Martinez, M.,Crublet, E.,Weber, P.,Girard-Blanc, C.,Petres, S.,Haouz, A.,Hernandez, J.F.,Mercereau-Puijalon, O.,Alzari, P.M.,Barale, J.C. A novel Plasmodium-specific prodomain fold regulates the malaria drug target SUB1 subtilase. Nat Commun, 5:4833-4833, 2014 Cited by PubMed: 25204226DOI: 10.1038/ncomms5833 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.7 Å) |
Structure validation
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