Author results

6QG0
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STRUCTURE OF EIF2B-EIF2 (PHOSPHORYLATED AT SER51) COMPLEX (MODEL 1)
Descriptor:Translation initiation factor eIF-2B subunit alpha, Translation initiation factor eIF-2B subunit beta, Translation initiation factor eIF-2B subunit gamma, ...
Authors:Llacer, J.L., Gordiyenko, Y., Ramakrishnan, V.
Deposit date:2019-01-10
Release date:2019-06-26
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Structural basis for the inhibition of translation through eIF2 alpha phosphorylation.
Nat Commun, 10, 2019
6QG1
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STRUCTURE OF EIF2B-EIF2 (PHOSPHORYLATED AT SER51) COMPLEX (MODEL 2)
Descriptor:Translation initiation factor eIF-2B subunit alpha, Translation initiation factor eIF-2B subunit beta, Translation initiation factor eIF-2B subunit gamma, ...
Authors:Llacer, J.L., Gordiyenko, Y., Ramakrishnan, V.
Deposit date:2019-01-10
Release date:2019-06-26
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Structural basis for the inhibition of translation through eIF2 alpha phosphorylation.
Nat Commun, 10, 2019
6QG2
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STRUCTURE OF EIF2B-EIF2 (PHOSPHORYLATED AT SER51) COMPLEX (MODEL A)
Descriptor:Translation initiation factor eIF-2B subunit alpha, Translation initiation factor eIF-2B subunit beta, Translation initiation factor eIF-2B subunit gamma, ...
Authors:Llacer, J.L., Gordiyenko, Y., Ramakrishnan, V.
Deposit date:2019-01-10
Release date:2019-06-26
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (4.6 Å)
Cite:Structural basis for the inhibition of translation through eIF2 alpha phosphorylation.
Nat Commun, 10, 2019
6QG3
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STRUCTURE OF EIF2B-EIF2 (PHOSPHORYLATED AT SER51) COMPLEX (MODEL B)
Descriptor:Translation initiation factor eIF-2B subunit alpha, Translation initiation factor eIF-2B subunit beta, Translation initiation factor eIF-2B subunit gamma, ...
Authors:Llacer, J.L., Gordiyenko, Y., Ramakrishnan, V.
Deposit date:2019-01-10
Release date:2019-06-26
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (9.4 Å)
Cite:Structural basis for the inhibition of translation through eIF2 alpha phosphorylation.
Nat Commun, 10, 2019
6QG5
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STRUCTURE OF EIF2B-EIF2 (PHOSPHORYLATED AT SER51) COMPLEX (MODEL C)
Descriptor:Translation initiation factor eIF-2B subunit alpha, Translation initiation factor eIF-2B subunit beta, Translation initiation factor eIF-2B subunit gamma, ...
Authors:Llacer, J.L., Gordiyenko, Y., Ramakrishnan, V.
Deposit date:2019-01-10
Release date:2019-06-26
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (10.1 Å)
Cite:Structural basis for the inhibition of translation through eIF2 alpha phosphorylation.
Nat Commun, 10, 2019
6QG6
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STRUCTURE OF EIF2B-EIF2 (PHOSPHORYLATED AT SER51) COMPLEX (MODEL D)
Descriptor:Translation initiation factor eIF-2B subunit alpha, Translation initiation factor eIF-2B subunit beta, Translation initiation factor eIF-2B subunit gamma, ...
Authors:Llacer, J.L., Gordiyenko, Y., Ramakrishnan, V.
Deposit date:2019-01-10
Release date:2019-06-26
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (4.65 Å)
Cite:Structural basis for the inhibition of translation through eIF2 alpha phosphorylation.
Nat Commun, 10, 2019
6GSM
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STRUCTURE OF A PARTIAL YEAST 48S PREINITIATION COMPLEX IN OPEN CONFORMATION
Descriptor:Met-tRNAi, 18S ribosomal RNA, 40S ribosomal protein S0, ...
Authors:Llacer, J.L., Hussain, T., Gordiyenko, Y., Ramakrishnan, V.
Deposit date:2018-06-14
Release date:2019-07-31
Method:ELECTRON MICROSCOPY (5.15 Å)
Cite:Towards a model of eIF3 on the 40S subunit interface in eukaryotic translation initiation
To Be Published
6GSN
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STRUCTURE OF A PARTIAL YEAST 48S PREINITIATION COMPLEX IN CLOSED CONFORMATION
Descriptor:18S rRNA (1798-MER), KLLA0F09812p, KLLA0D08305p, ...
Authors:Llacer, J.L., Hussain, T., Ramakrishnan, V.
Deposit date:2018-06-14
Release date:2019-06-26
Last modified:2019-07-03
Method:ELECTRON MICROSCOPY (5.75 Å)
Cite:Towards a model of eIF3 on the 40S subunit interface in eukaryotic translation initiation
To Be Published
6FYX
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STRUCTURE OF A PARTIAL YEAST 48S PREINITIATION COMPLEX WITH EIF5 N-TERMINAL DOMAIN (MODEL C1)
Descriptor:tRNAi, 18S ribosomal RNA, mRNA (31-MER), ...
Authors:Llacer, J.L., Hussain, T., Gordiyenko, Y., Ramakrishnan, V.
Deposit date:2018-03-12
Release date:2018-12-05
Last modified:2019-12-11
Method:ELECTRON MICROSCOPY (3.05 Å)
Cite:Translational initiation factor eIF5 replaces eIF1 on the 40S ribosomal subunit to promote start-codon recognition.
Elife, 7, 2018
6FYY
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STRUCTURE OF A PARTIAL YEAST 48S PREINITIATION COMPLEX WITH EIF5 N-TERMINAL DOMAIN (MODEL C2)
Descriptor:tRNAi, 18S ribosomal RNA, mRNA (31-MER), ...
Authors:Llacer, J.L., Hussain, T., Gordiyenko, Y., Ramakrishnan, V.
Deposit date:2018-03-12
Release date:2018-12-05
Last modified:2019-12-11
Method:ELECTRON MICROSCOPY (3.05 Å)
Cite:Translational initiation factor eIF5 replaces eIF1 on the 40S ribosomal subunit to promote start-codon recognition.
Elife, 7, 2018
5LMN
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STRUCTURE OF BACTERIAL 30S-IF1-IF3-MRNA TRANSLATION PRE-INITIATION COMPLEX (STATE-1A)
Descriptor:16S ribosomal RNA, 30S ribosomal protein S2, 30S ribosomal protein S3, ...
Authors:Hussain, T., Llacer, J.L., Wimberly, B.T., Ramakrishnan, V.
Deposit date:2016-08-01
Release date:2016-10-05
Last modified:2019-10-02
Method:ELECTRON MICROSCOPY (3.55 Å)
Cite:Large-Scale Movements of IF3 and tRNA during Bacterial Translation Initiation.
Cell, 167, 2016
5LMO
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STRUCTURE OF BACTERIAL 30S-IF1-IF3-MRNA TRANSLATION PRE-INITIATION COMPLEX (STATE-1B)
Descriptor:16S rRNA, 30S ribosomal protein S2, 30S ribosomal protein S3, ...
Authors:Hussain, T., Llacer, J.L., Wimberly, B.T., Ramakrishnan, V.
Deposit date:2016-08-01
Release date:2016-10-05
Last modified:2019-10-02
Method:ELECTRON MICROSCOPY (4.3 Å)
Cite:Large-Scale Movements of IF3 and tRNA during Bacterial Translation Initiation.
Cell, 167, 2016
5LMP
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STRUCTURE OF BACTERIAL 30S-IF1-IF3-MRNA TRANSLATION PRE-INITIATION COMPLEX (STATE-1C)
Descriptor:16S rRNA, 30S ribosomal protein S2, 30S ribosomal protein S3, ...
Authors:Hussain, T., Llacer, J.L., Wimberly, B.T., Ramakrishnan, V.
Deposit date:2016-08-01
Release date:2016-10-05
Last modified:2019-10-02
Method:ELECTRON MICROSCOPY (5.35 Å)
Cite:Large-Scale Movements of IF3 and tRNA during Bacterial Translation Initiation.
Cell, 167, 2016
5LMQ
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STRUCTURE OF BACTERIAL 30S-IF1-IF3-MRNA-TRNA TRANSLATION PRE-INITIATION COMPLEX, OPEN FORM (STATE-2A)
Descriptor:16S rRNA, 30S ribosomal protein S2, 30S ribosomal protein S3, ...
Authors:Hussain, T., Llacer, J.L., Wimberly, B.T., Ramakrishnan, V.
Deposit date:2016-08-01
Release date:2016-10-05
Last modified:2019-12-11
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Large-Scale Movements of IF3 and tRNA during Bacterial Translation Initiation.
Cell, 167, 2016
5LMR
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STRUCTURE OF BACTERIAL 30S-IF1-IF3-MRNA-TRNA TRANSLATION PRE-INITIATION COMPLEX(STATE-2B)
Descriptor:16S rRNA, 30S ribosomal protein S2, 30S ribosomal protein S3, ...
Authors:Hussain, T., Llacer, J.L., Wimberly, B.T., Ramakrishnan, V.
Deposit date:2016-08-01
Release date:2016-10-05
Last modified:2019-10-02
Method:ELECTRON MICROSCOPY (4.45 Å)
Cite:Large-Scale Movements of IF3 and tRNA during Bacterial Translation Initiation.
Cell, 167, 2016
5LMS
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STRUCTURE OF BACTERIAL 30S-IF1-IF3-MRNA-TRNA TRANSLATION PRE-INITIATION COMPLEX(STATE-2C)
Descriptor:16S rRNA, 30S ribosomal protein S2, 30S ribosomal protein S3, ...
Authors:Hussain, T., Llacer, J.L., Wimberly, B.T., Ramakrishnan, V.
Deposit date:2016-08-01
Release date:2016-10-05
Last modified:2019-10-02
Method:ELECTRON MICROSCOPY (5.1 Å)
Cite:Large-Scale Movements of IF3 and tRNA during Bacterial Translation Initiation.
Cell, 167, 2016
5LMT
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STRUCTURE OF BACTERIAL 30S-IF1-IF3-MRNA-TRNA TRANSLATION PRE-INITIATION COMPLEX(STATE-3)
Descriptor:16S ribosomal RNA, 30S ribosomal protein S2, 30S ribosomal protein S3, ...
Authors:Hussain, T., Llacer, J.L., Wimberly, B.T., Ramakrishnan, V.
Deposit date:2016-08-01
Release date:2016-10-05
Last modified:2019-12-11
Method:ELECTRON MICROSCOPY (4.15 Å)
Cite:Large-Scale Movements of IF3 and tRNA during Bacterial Translation Initiation.
Cell, 167, 2016
5LMU
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STRUCTURE OF BACTERIAL 30S-IF3-MRNA-TRNA TRANSLATION PRE-INITIATION COMPLEX, CLOSED FORM (STATE-4)
Descriptor:16S ribosomal RNA, 30S ribosomal protein S2, 30S ribosomal protein S3, ...
Authors:Hussain, T., Llacer, J.L., Wimberly, B.T., Ramakrishnan, V.
Deposit date:2016-08-01
Release date:2016-10-05
Last modified:2019-10-02
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Large-Scale Movements of IF3 and tRNA during Bacterial Translation Initiation.
Cell, 167, 2016
5LMV
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STRUCTURE OF BACTERIAL 30S-IF1-IF2-IF3-MRNA-TRNA TRANSLATION PRE-INITIATION COMPLEX(STATE-III)
Descriptor:16S ribosomal RNA, 30S ribosomal protein S2, 30S ribosomal protein S3, ...
Authors:Hussain, T., Llacer, J.L., Wimberly, B.T., Ramakrishnan, V.
Deposit date:2016-08-01
Release date:2016-10-05
Last modified:2019-12-11
Method:ELECTRON MICROSCOPY (4.9 Å)
Cite:Large-Scale Movements of IF3 and tRNA during Bacterial Translation Initiation.
Cell, 167, 2016
3JAP
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STRUCTURE OF A PARTIAL YEAST 48S PREINITIATION COMPLEX IN CLOSED CONFORMATION
Descriptor:Met-tRNAi (U31:A39 variant), 18S rRNA, mRNA, ...
Authors:Llacer, J.L., Hussain, T., Ramakrishnan, V.
Deposit date:2015-06-18
Release date:2015-08-12
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (4.9 Å)
Cite:Conformational Differences between Open and Closed States of the Eukaryotic Translation Initiation Complex.
Mol.Cell, 59, 2015
3JAQ
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STRUCTURE OF A PARTIAL YEAST 48S PREINITIATION COMPLEX IN OPEN CONFORMATION
Descriptor:Met-tRNAi, 18S rRNA, mRNA, ...
Authors:Llacer, J.L., Hussain, T., Ramakrishnan, V.
Deposit date:2015-06-18
Release date:2015-08-12
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (6 Å)
Cite:Conformational Differences between Open and Closed States of the Eukaryotic Translation Initiation Complex.
Mol.Cell, 59, 2015
3JAM
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CRYOEM STRUCTURE OF 40S-EIF1A-EIF1 COMPLEX FROM YEAST
Descriptor:18S rRNA, uS2, eS1, ...
Authors:Llacer, J.L., Hussain, T., Ramakrishnan, V.
Deposit date:2015-06-17
Release date:2015-08-12
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (3.46 Å)
Cite:Conformational Differences between Open and Closed States of the Eukaryotic Translation Initiation Complex.
Mol.Cell, 59, 2015
3J81
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CRYOEM STRUCTURE OF A PARTIAL YEAST 48S PREINITIATION COMPLEX
Descriptor:18S rRNA, uS2, eS1, ...
Authors:Hussain, T., Llacer, J.L., Fernandez, I.S., Savva, C.G., Ramakrishnan, V.
Deposit date:2014-08-29
Release date:2014-11-05
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Structural changes enable start codon recognition by the eukaryotic translation initiation complex.
Cell(Cambridge,Mass.), 159, 2014
3J80
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CRYOEM STRUCTURE OF 40S-EIF1-EIF1A PREINITIATION COMPLEX
Descriptor:18S rRNA, uS2, eS1, ...
Authors:Hussain, T., Llacer, J.L., Fernandez, I.S., Savva, C.G., Ramakrishnan, V.
Deposit date:2014-08-28
Release date:2014-11-05
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (3.75 Å)
Cite:Structural changes enable start codon recognition by the eukaryotic translation initiation complex.
Cell(Cambridge,Mass.), 159, 2014
4OZJ
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GLNK2 FROM HALOFERAX MEDITERRANEI COMPLEXED WITH ADP
Descriptor:Nitrogen regulatory protein P-II, ADENOSINE-5'-DIPHOSPHATE
Authors:Palanca, C., Pedro-Roig, L., Llacer, J.L., Camacho, M., Bonete, M.J., Rubio, V.
Deposit date:2014-02-17
Release date:2014-07-02
Last modified:2014-10-01
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:The structure of a PII signaling protein from a halophilic archaeon reveals novel traits and high-salt adaptations.
Febs J., 281, 2014
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