Author results

1AKH
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MAT A1/ALPHA2/DNA TERNARY COMPLEX
Descriptor:DNA (5'-D(*TP*AP*CP*AP*TP*GP*TP*AP*AP*AP*AP*AP*TP*TP*TP*AP*C P*AP*TP*CP*A)-3'), DNA (5'-D(*TP*AP*TP*GP*AP*TP*GP*TP*AP*AP*AP*TP*TP*TP*TP*TP*A P*CP*AP*TP*G)-3'), PROTEIN (MATING-TYPE PROTEIN A-1), ...
Authors:Li, T., Jin, Y., Vershon, A.K., Wolberger, C.
Deposit date:1997-05-19
Release date:1998-05-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of the MATa1/MATalpha2 homeodomain heterodimer in complex with DNA containing an A-tract.
Nucleic Acids Res., 26, 1998
6JAU
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THE COMPLEX STRUCTURE OF PSEUDOMONAS AERUGINOSA MUCA/MUCB.
Descriptor:Sigma factor AlgU regulatory protein MucB, Sigma factor AlgU negative regulatory protein, CALCIUM ION, ...
Authors:Li, T., He, L.H., Li, C.C., Liu, L., Peng, C.T., Shen, Y.L., Qin, X.F., Xiao, Q.J., Zhu, Y.B., Song, Y.J., Zhao, N.l., Zhao, C., Yang, J., Mu, X.Y., Huang, Q., Bao, R.
Deposit date:2019-01-25
Release date:2020-01-29
Method:X-RAY DIFFRACTION (1.905 Å)
Cite:The complex structure of Pseudomonas aeruginosa MucA/MucB.
To Be Published
7C8V
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STRUCTURE OF SYBODY SR4 IN COMPLEX WITH THE SARS-COV-2 S RECEPTOR BINDING DOMAIN (RBD)
Descriptor:Synthetic nanobody SR4, Spike glycoprotein, GLYCEROL, ...
Authors:Li, T., Yao, H., Cai, H., Qin, W., Li, D.
Deposit date:2020-06-03
Release date:2020-06-24
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Potent synthetic nanobodies against SARS-CoV-2 and molecular basis for neutratlization
To Be Published
7C8W
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STRUCTURE OF SYBODY MR17 IN COMPLEX WITH THE SARS-COV-2 S RECEPTOR-BINDING DOMAIN (RBD)
Descriptor:Synthetic nanobody MR17, Spike glycoprotein, alpha-L-fucopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)][alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Li, T., Cai, H., Yao, H., Qin, W., Li, D.
Deposit date:2020-06-03
Release date:2020-06-24
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.77 Å)
Cite:Rapid selection of synthetic nanobodies against the receptor binding domain of SARS-CoV-2 S protein
To Be Published
7CAN
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STRUCTURE OF SYBODY MR17-K99Y IN COMPLEX WITH THE SARS-COV-2 S RECEPTOR-BINDING DOMAIN (RBD)
Descriptor:sybody MR17-K99Y, Spike glycoprotein, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Li, T., Yao, H., Cai, H., Qin, W., Li, D.
Deposit date:2020-06-09
Release date:2020-06-24
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.94 Å)
Cite:Potent synthetic nanobodies against SARS-CoV-2 and molecular basis for neutratlization
To Be Published
1KU5
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CRYSTAL STRUCTURE OF RECOMBINANT HISTONE HPHA FROM HYPERTHERMOPHILIC ARCHAEON PYROCOCCUS HORIKOSHII OT3
Descriptor:HPhA, ACETATE ION, SULFATE ION
Authors:Li, T., Sun, F., Ji, X., Feng, Y., Rao, Z.
Deposit date:2002-01-21
Release date:2003-08-26
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure based hyperthermostability of archaeal histone HPhA from Pyrococcus horikoshii
J.MOL.BIOL., 325, 2003
1YRN
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CRYSTAL STRUCTURE OF THE MATA1/MATALPHA2 HOMEODOMAIN HETERODIMER BOUND TO DNA
Descriptor:DNA (5'-D(*TP*AP*CP*AP*TP*GP*TP*AP*AP*TP*TP*TP*AP*TP*TP*AP*C P*AP*TP*CP*A)-3'), DNA (5'-D(*TP*AP*TP*GP*AP*TP*GP*TP*AP*AP*TP*AP*AP*AP*TP*TP*A P*CP*AP*TP*G)-3'), PROTEIN (MAT A1 HOMEODOMAIN), ...
Authors:Li, T., Stark, M.R., Johnson, A.D., Wolberger, C.
Deposit date:1995-11-02
Release date:1996-01-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of the MATa1/MAT alpha 2 homeodomain heterodimer bound to DNA.
Science, 270, 1995
5Z0R
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STRUCTURAL INSIGHT INTO THE ZIKA VIRUS CAPSID ENCAPSULATING THE VIRAL GENOME
Descriptor:Extracellular solute-binding protein family 1,viral genome protein, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose
Authors:Li, T., Zhao, Q., Yang, X., Chen, C., Yang, K., Wu, C., Zhang, T., Duan, Y., Xue, X., Mi, K., Ji, X., Wang, Z., Yang, H.
Deposit date:2017-12-20
Release date:2018-04-11
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Structural insight into the Zika virus capsid encapsulating the viral genome.
Cell Res., 28, 2018
5Z0V
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STRUCTURAL INSIGHT INTO THE ZIKA VIRUS CAPSID ENCAPSULATING THE VIRAL GENOME
Descriptor:Extracellular solute-binding protein family 1,viral genome protein, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose
Authors:Li, T., Zhao, Q., Yang, X., Chen, C., Yang, K., Wu, C., Zhang, T., Duan, Y., Xue, X., Mi, K., Ji, X., Wang, Z., Yang, H.
Deposit date:2017-12-21
Release date:2018-04-11
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.913 Å)
Cite:Structural insight into the Zika virus capsid encapsulating the viral genome.
Cell Res., 28, 2018
1MYM
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STRUCTURAL DETERMINANTS OF CO STRETCHING VIBRATION FREQUENCIES IN MYOGLOBIN
Descriptor:MYOGLOBIN, SULFATE ION, PROTOPORPHYRIN IX CONTAINING FE, ...
Authors:Li, T., Phillips Jr., G.N.
Deposit date:1993-10-14
Release date:1994-01-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural determinants of the stretching frequency of CO bound to myoglobin.
Biochemistry, 33, 1994
2B5L
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CRYSTAL STRUCTURE OF DDB1 IN COMPLEX WITH SIMIAN VIRUS 5 V PROTEIN
Descriptor:damage-specific DNA binding protein 1, Nonstructural protein V, ZINC ION
Authors:Li, T., Chen, X., Garbutt, K.C., Zhou, P., Zheng, N.
Deposit date:2005-09-28
Release date:2006-02-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Structure of DDB1 in complex with a paramyxovirus V protein: viral hijack of a propeller cluster in ubiquitin ligase.
Cell(Cambridge,Mass.), 124, 2006
2B5M
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CRYSTAL STRUCTURE OF DDB1
Descriptor:damage-specific DNA binding protein 1
Authors:Li, T., Chen, X., Garbutt, K.C., Zhou, P., Zheng, N.
Deposit date:2005-09-28
Release date:2006-02-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.92 Å)
Cite:Structure of DDB1 in complex with a paramyxovirus V protein: viral hijack of a propeller cluster in ubiquitin ligase.
Cell(Cambridge,Mass.), 124, 2006
2B5N
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CRYSTAL STRUCTURE OF THE DDB1 BPB DOMAIN
Descriptor:damage-specific DNA binding protein 1, ISOPROPYL ALCOHOL
Authors:Li, T., Chen, X., Garbutt, K.C., Zhou, P., Zheng, N.
Deposit date:2005-09-28
Release date:2006-02-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structure of DDB1 in complex with a paramyxovirus V protein: viral hijack of a propeller cluster in ubiquitin ligase.
Cell(Cambridge,Mass.), 124, 2006
3I7H
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CRYSTAL STRUCTURE OF DDB1 IN COMPLEX WITH THE H-BOX MOTIF OF HBX
Descriptor:DNA damage-binding protein 1, X protein
Authors:Li, T., Robert, E.I., Breugel, P.C.V., Strubin, M., Zheng, N.
Deposit date:2009-07-08
Release date:2009-12-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:A promiscuous alpha-helical motif anchors viral hijackers and substrate receptors to the CUL4-DDB1 ubiquitin ligase machinery.
Nat.Struct.Mol.Biol., 17, 2010
3I7K
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CRYSTAL STRUCTURE OF DDB1 IN COMPLEX WITH THE H-BOX MOTIF OF WHX
Descriptor:DNA damage-binding protein 1, X protein
Authors:Li, T., Robert, E.I., Breugel, P.C.V., Strubin, M., Zheng, N.
Deposit date:2009-07-08
Release date:2009-12-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:A promiscuous alpha-helical motif anchors viral hijackers and substrate receptors to the CUL4-DDB1 ubiquitin ligase machinery.
Nat.Struct.Mol.Biol., 17, 2010
3I7L
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CRYSTAL STRUCTURE OF DDB1 IN COMPLEX WITH THE H-BOX MOTIF OF DDB2
Descriptor:DNA damage-binding protein 1, DNA damage-binding protein 2
Authors:Li, T., Robert, E.I., Breugel, P.C.V., Strubin, M., Zheng, N.
Deposit date:2009-07-08
Release date:2009-12-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:A promiscuous alpha-helical motif anchors viral hijackers and substrate receptors to the CUL4-DDB1 ubiquitin ligase machinery.
Nat.Struct.Mol.Biol., 17, 2010
3I7N
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CRYSTAL STRUCTURE OF DDB1 IN COMPLEX WITH THE H-BOX MOTIF OF WDTC1
Descriptor:DNA damage-binding protein 1, WD and tetratricopeptide repeats protein 1
Authors:Li, T., Robert, E.I., Breugel, P.C.V., Strubin, M., Zheng, N.
Deposit date:2009-07-08
Release date:2009-12-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:A promiscuous alpha-helical motif anchors viral hijackers and substrate receptors to the CUL4-DDB1 ubiquitin ligase machinery.
Nat.Struct.Mol.Biol., 17, 2010
3I7O
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CRYSTAL STRUCTURE OF DDB1 IN COMPLEX WITH THE H-BOX MOTIF OF IQWD1
Descriptor:DNA damage-binding protein 1, IQ motif and WD repeat-containing protein 1
Authors:Li, T., Robert, E.I., Breugel, P.C.V., Strubin, M., Zheng, N.
Deposit date:2009-07-08
Release date:2009-12-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:A promiscuous alpha-helical motif anchors viral hijackers and substrate receptors to the CUL4-DDB1 ubiquitin ligase machinery.
Nat.Struct.Mol.Biol., 17, 2010
3I7P
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CRYSTAL STRUCTURE OF DDB1 IN COMPLEX WITH THE H-BOX MOTIF OF WDR40A
Descriptor:DNA damage-binding protein 1, WD repeat-containing protein 40A
Authors:Li, T., Robert, E.I., Breugel, P.C.V., Strubin, M., Zheng, N.
Deposit date:2009-07-08
Release date:2009-12-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:A promiscuous alpha-helical motif anchors viral hijackers and substrate receptors to the CUL4-DDB1 ubiquitin ligase machinery.
Nat.Struct.Mol.Biol., 17, 2010
3I89
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CRYSTAL STRUCTURE OF DDB1 IN COMPLEX WITH THE H-BOX MOTIF OF WDR22
Descriptor:DNA damage-binding protein 1, WD repeat-containing protein 22
Authors:Li, T., Robert, E.I., Breugel, P.C.V., Strubin, M., Zheng, N.
Deposit date:2009-07-09
Release date:2009-12-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:A promiscuous alpha-helical motif anchors viral hijackers and substrate receptors to the CUL4-DDB1 ubiquitin ligase machinery.
Nat.Struct.Mol.Biol., 17, 2010
3I8C
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CRYSTAL STRUCTURE OF DDB1 IN COMPLEX WITH THE H-BOX MOTIF OF WDR21A
Descriptor:DNA damage-binding protein 1, WD repeat-containing protein 21A
Authors:Li, T., Robert, E.I., Breugel, P.C.V., Strubin, M., Zheng, N.
Deposit date:2009-07-09
Release date:2009-12-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:A promiscuous alpha-helical motif anchors viral hijackers and substrate receptors to the CUL4-DDB1 ubiquitin ligase machinery.
Nat.Struct.Mol.Biol., 17, 2010
3I8E
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CRYSTAL STRUCTURE OF DDB1 IN COMPLEX WITH THE H-BOX MOTIF OF WDR42A
Descriptor:DNA damage-binding protein 1, WD repeat-containing protein 42A
Authors:Li, T., Robert, E.I., Breugel, P.C.V., Strubin, M., Zheng, N.
Deposit date:2009-07-09
Release date:2009-12-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:A promiscuous alpha-helical motif anchors viral hijackers and substrate receptors to the CUL4-DDB1 ubiquitin ligase machinery.
Nat.Struct.Mol.Biol., 17, 2010
6CGC
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CRYSTAL STRUCTURE OF HUMAN 17BETA-HSD TYPE 1 IN TERNARY COMPLEX WITH 2-MEO-CC-156 AND NADP+
Descriptor:Estradiol 17-beta-dehydrogenase 1, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, 3-{[(9beta,14beta,16alpha,17alpha)-3,17-dihydroxy-2-methoxyestra-1,3,5(10)-trien-16-yl]methyl}benzamide
Authors:Li, T., Lin, S.X.
Deposit date:2018-02-19
Release date:2019-01-16
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Combined Biophysical Chemistry Reveals a New Covalent Inhibitor with a Low-Reactivity Alkyl Halide.
J Phys Chem Lett, 9, 2018
6CGE
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CRYSTAL STRUCTURE OF HUMAN 17BETA-HSD TYPE 1 IN TERNARY COMPLEX WITH PBRM AND NADP+
Descriptor:Estradiol 17-beta-dehydrogenase 1, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, 3-{[(14beta,16alpha,17alpha)-3-(2-bromoethyl)-17-hydroxyestra-1,3,5(10)-trien-16-yl]methyl}benzamide
Authors:Li, T., Lin, S.X.
Deposit date:2018-02-20
Release date:2019-01-16
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Combined Biophysical Chemistry Reveals a New Covalent Inhibitor with a Low-Reactivity Alkyl Halide.
J Phys Chem Lett, 9, 2018
6DTP
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CRYSTAL STRUCTURE OF HUMAN 17BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 1 COMPLEXED WITH EM139
Descriptor:Estradiol 17-beta-dehydrogenase 1, GLYCEROL, 1,2-ETHANEDIOL, ...
Authors:Li, T., Lin, S.X.
Deposit date:2018-06-18
Release date:2018-09-12
Method:X-RAY DIFFRACTION (2 Å)
Cite:CRYSTAL STRUCTURE OF HUMAN 17BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 1 COMPLEXED WITH Dual-Site Inhibitor EM-139
Health, 2018
167132
PDB entries from 2020-07-29