3I8E

Crystal Structure of DDB1 in Complex with the H-Box Motif of WDR42A

Summary for 3I8E

Entry DOI	10.2210/pdb3i8e/pdb
Related	2B5M 3I7H 3I7K 3I7L 3I7N 3I7O 3I7P 3I89 3I8C
Descriptor	DNA damage-binding protein 1, WD repeat-containing protein 42A (2 entities in total)
Functional Keywords	ddb1, wdr42a, h326, dcaf8, h-box motif, dna damage, dna repair, dna-binding, host-virus interaction, nucleus, phosphoprotein, ubl conjugation pathway, wd repeat, protein binding
Biological source	Homo sapiens (human) More
Cellular location	Cytoplasm: Q16531
Total number of polymer chains	4
Total formula weight	257682.80
Authors	Li, T.,Robert, E.I.,Breugel, P.C.V.,Strubin, M.,Zheng, N. (deposition date: 2009-07-09, release date: 2009-12-08, Last modification date: 2023-09-06)
Primary citation	Li, T.,Robert, E.I.,van Breugel, P.C.,Strubin, M.,Zheng, N. A promiscuous alpha-helical motif anchors viral hijackers and substrate receptors to the CUL4-DDB1 ubiquitin ligase machinery. Nat.Struct.Mol.Biol., 17:105-111, 2010 Cited by PubMed: 19966799 DOI: 10.1038/nsmb.1719 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.4 Å)

Structure validation