Structure of sybody MR17-K99Y in complex with the SARS-CoV-2 S Receptor-binding domain (RBD)

Summary for 7CAN

Descriptorsybody MR17-K99Y, Spike glycoprotein, N-ACETYL-D-GLUCOSAMINE, ... (5 entities in total)
Functional Keywordscoronavirus, covid-19, nanobody, neutralizing antibody, receptor binding protein, sars-cov-2, s protein, synthetic antibody, vhh., protein binding
Biological sourcesynthetic construct
Total number of polymer chains2
Total molecular weight41019.41
Li, T.,Yao, H.,Cai, H.,Qin, W.,Li, D. (deposition date: 2020-06-09, release date: 2020-06-24)
Primary citation
Li, T.,Cai, H.,Yao, H.,Zhou, B.,Zhao, Y.,Qin, W.,Lavillette, D.,Li, D.
Potent synthetic nanobodies against SARS-CoV-2 and molecular basis for neutratlization
To Be Published,
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.2687 0.3% 4.3% 4.5%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
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