Author results

3QNF
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CRYSTAL STRUCTURE OF THE OPEN STATE OF HUMAN ENDOPLASMIC RETICULUM AMINOPEPTIDASE 1 ERAP1
分子名称:Endoplasmic reticulum aminopeptidase 1, ZINC ION, N-ACETYL-D-GLUCOSAMINE, ...
著者Vollmar, M., Kochan, G., Krojer, T., Harvey, D., Chaikuad, A., Allerston, C., Muniz, J.R.C., Raynor, J., Ugochukwu, E., Berridge, G., Wordsworth, B.P., von Delft, F., Bountra, C., Arrowsmith, C.H., Edwards, A., Kavanagh, K., Oppermann, U., Structural Genomics Consortium (SGC)
登録日2011-02-08
公開日2011-02-23
最終更新日2018-01-31
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Crystal structures of the endoplasmic reticulum aminopeptidase-1 (ERAP1) reveal the molecular basis for N-terminal peptide trimming.
Proc.Natl.Acad.Sci.USA, 108, 2011
2YD0
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CRYSTAL STRUCTURE OF THE SOLUBLE DOMAIN OF HUMAN ENDOPLASMIC RETICULUM AMINOPEPTIDASE 1 ERAP1
分子名称:ENDOPLASMIC RETICULUM AMINOPEPTIDASE 1, N-ACETYL-D-GLUCOSAMINE, ZINC ION, ...
著者Vollmar, M., Kochan, G., Krojer, T., Ugochukwu, E., Muniz, J.R.C., Raynor, J., Chaikuad, A., Allerston, C., von Delft, F., Bountra, C., Arrowsmith, C.H., Weigelt, J., Edwards, A., Knapp, S.
登録日2011-03-17
公開日2011-04-13
最終更新日2019-04-03
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Crystal Structures of the Endoplasmic Reticulum Aminopeptidase-1 (Erap1) Reveal the Molecular Basis for N-Terminal Peptide Trimming.
Proc.Natl.Acad.Sci.USA, 108, 2011
3EQ6
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CRYSTAL STRUCTURE OF HUMAN ACYL-COA SYNTHETASE MEDIUM-CHAIN FAMILY MEMBER 2A (L64P MUTATION) IN A TERNARY COMPLEX WITH PRODUCTS
分子名称:Acyl-coenzyme A synthetase ACSM2A, ADENOSINE MONOPHOSPHATE, Butyryl Coenzyme A
著者Pilka, E.S., Kochan, G., Yue, W.W., Bhatia, C., Von delft, F., Arrowsmith, C.H., Edwards, A.M., Weigelt, J., Bountra, C., Oppermann, U., Structural Genomics Consortium (SGC)
登録日2008-09-30
公開日2008-10-28
最終更新日2016-02-03
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural snapshots for the conformation-dependent catalysis by human medium-chain acyl-coenzyme A synthetase ACSM2A
J.Mol.Biol., 388, 2009
4B87
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CRYSTAL STRUCTURE OF HUMAN DNA CROSS-LINK REPAIR 1A
分子名称:DNA CROSS-LINK REPAIR 1A PROTEIN, ZINC ION, 1,2-ETHANEDIOL
著者Allerston, C.K., Berridge, G., Carpenter, E.P., Kochan, G., Krojer, T., Mahajan, P., Vollmar, M., Yue, W.W., Arrowsmith, C.H., Edwards, A., Bountra, C., von Delft, F., Gileadi, O.
登録日2012-08-24
公開日2012-11-28
最終更新日2018-01-24
実験手法X-RAY DIFFRACTION (2.16 Å)
主引用文献Crystal Structure of Human DNA Cross-Link Repair 1A
To be Published
2JKU
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CRYSTAL STRUCTURE OF THE N-TERMINAL REGION OF THE BIOTIN ACCEPTOR DOMAIN OF HUMAN PROPIONYL-COA CARBOXYLASE
分子名称:PROPIONYL-COA CARBOXYLASE ALPHA CHAIN, MITOCHONDRIAL, TETRAETHYLENE GLYCOL
著者Healy, S., Yue, W.W., Kochan, G., Pilka, E.S., Murray, J.W., Roos, A.K., Filippakopoulos, P., von Delft, F., Arrowsmith, C., Wikstrom, M., Edwards, A., Bountra, C., Gravel, R.A., Oppermann, U.
登録日2008-08-30
公開日2008-09-09
最終更新日2018-02-28
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Structural impact of human and Escherichia coli biotin carboxyl carrier proteins on biotin attachment.
Biochemistry, 49, 2010
2VNA
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STRUCTURE OF HUMAN ZINC-BINDING ALCOHOL DEHYDROGENASE 1 (ZADH1)
分子名称:PROSTAGLANDIN REDUCTASE 2, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Shafqat, N., Kavanagh, K., Pike, A.C.W., Muniz, J.R.C., Pilka, E., Roos, A.K., Picaud, S., Johansson, C., Smee, C., Fedorov, O., Kochan, G., Edwards, A., Arrowsmith, C.H., Weigelt, J., Bountra, C., von Delft, F., Opperman, U.
登録日2008-02-01
公開日2009-02-17
最終更新日2019-09-18
実験手法X-RAY DIFFRACTION (2.17 Å)
主引用文献Structure of Human Zinc-Binding Alcohol Dehydrogenase 1 (Zadh1)
To be Published
2VRE
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CRYSTAL STRUCTURE OF HUMAN PEROXISOMAL DELTA3,5,DELTA2,4-DIENOYL COA ISOMERASE
分子名称:DELTA(3,5)-DELTA(2,4)-DIENOYL-COA ISOMERASE, CHLORIDE ION
著者Yue, W., Guo, K., von Delft, F., Pilka, E., Murray, J., Roos, A., Kochan, G., Bountra, C., Arrowsmith, C., Wikstrom, M., Edwards, A., Oppermann, U.
登録日2008-03-31
公開日2008-04-15
最終更新日2018-01-24
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Crystal Structure of Human Peroxisomal Delta3,5, Delta2,4-Dienoyl Coa Isomerase (Ech1)
To be Published
2VSV
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CRYSTAL STRUCTURE OF THE PDZ DOMAIN OF HUMAN RHOPHILIN-2
分子名称:RHOPHILIN-2
著者Pike, A.C.W., Kochan, G., Sun, Z., Shafqat, N., Pilka, E.S., Roos, A., Elkins, J., Burgess-Brown, N., Murray, J.W., von Delft, F., Wikstrom, M., Edwards, A., Arrowsmith, C.H., Bountra, C., Oppermann, U.
登録日2008-04-29
公開日2008-07-15
最終更新日2018-01-24
実験手法X-RAY DIFFRACTION (1.82 Å)
主引用文献Crystal Structure of the Pdz Domain of Human Rhophilin-2
To be Published
2VX2
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CRYSTAL STRUCTURE OF HUMAN ENOYL COENZYME A HYDRATASE DOMAIN- CONTAINING PROTEIN 3 (ECHDC3)
分子名称:ENOYL-COA HYDRATASE DOMAIN-CONTAINING PROTEIN 3
著者Yue, W.W., Guo, K., Kochan, G., Pilka, E., Murray, J.W., Salah, E., Cocking, R., Sun, Z., Roos, A.K., Pike, A.C.W., Filippakopoulos, P., Arrowsmith, C., Wikstrom, M., Edwards, A., Bountra, C., Oppermann, U.
登録日2008-06-30
公開日2008-10-14
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal Structure of Human Enoyl Coenzyme a Hydratase Domain-Containing Protein 3 (Echdc3)
To be Published
2W2J
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CRYSTAL STRUCTURE OF THE HUMAN CARBONIC ANHYDRASE RELATED PROTEIN VIII
分子名称:CARBONIC ANHYDRASE-RELATED PROTEIN, CHLORIDE ION, GLYCEROL, ...
著者Kramm, A., Muniz, J.R.C., Picaud, S.S., von Delft, F., Pilka, E.S., Yue, W.W., King, O.N.F., Kochan, G., Pike, A.C.W., Filippakopoulos, P., Arrowsmith, C., Wikstrom, M., Edwards, A., Bountra, C., Oppermann, U.
登録日2008-10-31
公開日2009-02-03
最終更新日2012-02-22
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Crystal Structure of Human Carbonic Anhydrase-Related Protein Viii Reveals the Basis for Catalytic Silencing.
Proteins, 76, 2009
2WWW
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CRYSTAL STRUCTURE OF METHYLMALONIC ACIDEMIA TYPE A PROTEIN
分子名称:METHYLMALONIC ACIDURIA TYPE A PROTEIN, MITOCHONDRIAL, NONAETHYLENE GLYCOL, ...
著者Muniz, J.R.C., Gileadi, C., Froese, D.S., Yue, W.W., Pike, A.C.W., von Delft, F., Kochan, G., Sethi, R., Chaikuad, A., Pilka, E., Picaud, S., Phillips, C., Guo, K., Krysztofinska, E., Bray, J., Burgess-Brown, N., Arrowsmith, C.H., Weigelt, J., Edwards, A., Bountra, C., Gravel, R.A., Kavanagh, K.L., Oppermann, U.
登録日2009-10-30
公開日2009-11-17
最終更新日2013-11-27
実験手法X-RAY DIFFRACTION (2.64 Å)
主引用文献Structures of the Human Gtpase Mmaa and Vitamin B12-Dependent Methylmalonyl-Coa Mutase and Insight Into Their Complex Formation.
J.Biol.Chem., 285, 2010
2XIJ
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CRYSTAL STRUCTURE OF HUMAN METHYLMALONYL-COA MUTASE IN COMPLEX WITH ADENOSYLCOBALAMIN
分子名称:METHYLMALONYL-COA MUTASE, MITOCHONDRIAL, 5'-DEOXYADENOSINE, ...
著者Yue, W.W., Froese, D.S., Kochan, G., Chaikuad, A., Krojer, T., Muniz, J., Vollmar, M., Arrowsmith, C., Weigelt, J., Edwards, A., Bountra, C., Oppermann, U.
登録日2010-06-30
公開日2010-09-29
最終更新日2012-10-31
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Structures of the Human Gtpase Mmaa and Vitamin B12-Dependent Methylmalonyl-Coa Mutase and Insight Into Their Complex Formation.
J.Biol.Chem., 285, 2010
2XIQ
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CRYSTAL STRUCTURE OF HUMAN METHYLMALONYL-COA MUTASE IN COMPLEX WITH ADENOSYLCOBALAMIN AND MALONYL-COA
分子名称:METHYLMALONYL-COA MUTASE, MITOCHONDRIAL, COBALAMIN, ...
著者Yue, W.W., Froese, D.S., Kochan, G., Chaikuad, A., Krojer, T., Muniz, J., Ugochukwu, E., Arrowsmith, C., Weigelt, J., Edwards, A., Bountra, C., Oppermann, U.
登録日2010-06-30
公開日2010-09-29
最終更新日2019-11-20
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Structures of the Human Gtpase Mmaa and Vitamin B12-Dependent Methylmalonyl-Coa Mutase and Insight Into Their Complex Formation.
J.Biol.Chem., 285, 2010
3BIC
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CRYSTAL STRUCTURE OF HUMAN METHYLMALONYL-COA MUTASE
分子名称:Methylmalonyl-CoA mutase, mitochondrial precursor, CHLORIDE ION
著者Ugochukwu, E., Kochan, G., Pantic, N., Parizotto, E., Pilka, E.S., Pike, A.C.W., Gileadi, O., von Delft, F., Arrowsmith, C.H., Weigelt, J., Edwards, A.M., Oppermann, U., Structural Genomics Consortium (SGC)
登録日2007-11-30
公開日2007-12-25
最終更新日2017-10-25
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structures of the human GTPase MMAA and vitamin B12-dependent methylmalonyl-CoA mutase and insight into their complex formation.
J.Biol.Chem., 285, 2010
3CYN
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THE STRUCTURE OF HUMAN GPX8
分子名称:Probable glutathione peroxidase 8, SULFATE ION, GLYCEROL
著者Kavanagh, K.L., Johansson, C., Yue, W.W., Kochan, G., Pike, A.C.W., Murray, J., Roos, A.K., Filippakopoulos, P., von Delft, F., Arrowsmith, C.H., Wikstrom, M., Edwards, A.M., Bountra, C., Oppermann, U., Structural Genomics Consortium (SGC)
登録日2008-04-25
公開日2008-08-12
最終更新日2018-01-31
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献The structure of human GPX8
To be Published
3F3S
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THE CRYSTAL STRUCTURE OF HUMAN LAMBDA-CRYSTALLIN, CRYL1
分子名称:Lambda-crystallin homolog, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, SULFATE ION, ...
著者Ugochukwu, E., Johansson, C., Yue, W.W., Kochan, G., Pilka, E., Kramm, A., Pike, A.C.W., Filippakopoulos, P., von Delft, F., Bountra, C., Arrowsmith, C.H., Weigelt, J., Edwards, A., Oppermann, U., Structural Genomics Consortium (SGC)
登録日2008-10-31
公開日2008-11-25
最終更新日2019-10-23
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献The Crystal Structure of Human Lambda-Crystallin, CRYL1
To be Published
3FE4
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CRYSTAL STRUCTURE OF HUMAN CARBONIC ANHYDRASE VI
分子名称:Carbonic anhydrase 6, MAGNESIUM ION, GLYCEROL
著者Pilka, E.S., Kochan, G., Krysztofinska, E., Muniz, J., Yue, W.W., Roos, A.K., von Delft, F., Arrowsmith, C.H., Weigelt, J., Edwards, A., Bountra, C., Oppermann, U., Structural Genomics Consortium (SGC)
登録日2008-11-27
公開日2008-12-16
最終更新日2017-11-01
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structure of the secretory isozyme of mammalian carbonic anhydrases CA VI: implications for biological assembly and inhibitor development
Biochem.Biophys.Res.Commun., 419, 2012
3K2O
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STRUCTURE OF AN OXYGENASE
分子名称:Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6, NICKEL (II) ION, SODIUM ION, ...
著者Krojer, T., McDonough, M.A., Clifton, I.J., Mantri, M., Ng, S.S., Pike, A.C.W., Butler, D.S., Webby, C.J., Kochan, G., Bhatia, C., Bray, J.E., Chaikuad, A., Gileadi, O., von Delft, F., Weigelt, J., Arrowsmith, C.H., Bountra, C., Edwards, A.M., Schofield, C.J., Kavanagh, K.L., Oppermann, U., Structural Genomics Consortium (SGC)
登録日2009-09-30
公開日2009-11-03
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Crystal Structure of the 2-Oxoglutarate- and Fe(II)-Dependent Lysyl Hydroxylase JMJD6.
J.Mol.Biol., 401, 2010
3OOY
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CRYSTAL STRUCTURE OF HUMAN TRANSKETOLASE (TKT)
分子名称:Transketolase, THIAMIN DIPHOSPHATE, CALCIUM ION, ...
著者Krojer, T., Krysztofinska, E., Guo, K., Pilka, E., Kochan, G., Chaikuad, A., Vollmar, M., von Delft, F., Bountra, C., Arrowsmith, C.H., Weigelt, J., Edwards, A., Kavanagh, K., Oppermann, U., Structural Genomics Consortium (SGC)
登録日2010-08-31
公開日2010-11-17
最終更新日2014-02-19
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Crystal structure of human Transketolase (TKT)
To be Published
2VZE
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CRYSTAL STRUCTURE OF HUMAN ACYL-COA SYNTHETASE MEDIUM-CHAIN FAMILY MEMBER 2A (L64P MUTATION) IN COMPLEX WITH AMP
分子名称:ACYL-COENZYME A SYNTHETASE ACSM2A, MITOCHONDRIAL, ADENOSINE MONOPHOSPHATE, ...
著者Yue, W.W., Kochan, G.T., Pilka, E.S., Bhatia, C., von Delft, F., Arrowsmith, C.H., Edwards, A.M., Wikstrom, M., Bountra, C., Oppermann, U.
登録日2008-07-31
公開日2008-10-14
最終更新日2019-03-27
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Structural Snapshots for the Conformation- Dependent Catalysis by Human Medium-Chain Acyl- Coenzyme a Synthetase Acsm2A.
J.Mol.Biol., 388, 2009
2WD9
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CRYSTAL STRUCTURE OF HUMAN ACYL-COA SYNTHETASE MEDIUM-CHAIN FAMILY MEMBER 2A (L64P MUTATION) IN COMPLEX WITH IBUPROFEN
分子名称:ACYL-COENZYME A SYNTHETASE ACSM2A, MITOCHONDRIAL, IBUPROFEN, ...
著者Yue, W.W., Kochan, G.T., Pilka, E.S., Bhatia, C., von Delft, F., Arrowsmith, C.H., Edwards, A.M., Weigelt, J., Bountra, C., Oppermann, U.
登録日2009-03-21
公開日2009-04-21
最終更新日2019-04-03
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural Snapshots for the Conformation- Dependent Catalysis by Human Medium-Chain Acyl- Coenzyme a Synthetase Acsm2A.
J.Mol.Biol., 388, 2009
3B7W
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CRYSTAL STRUCTURE OF HUMAN ACYL-COA SYNTHETASE MEDIUM-CHAIN FAMILY MEMBER 2A, WITH L64P MUTATION
分子名称:Acyl-coenzyme A synthetase ACSM2A, mitochondrial precursor, MAGNESIUM ION, ...
著者Pilka, E.S., Kochan, G.T., Pike, A.C.W., von Delft, F., Arrowsmith, C.H., Edwards, A.M., Weigelt, J., Oppermann, U., Structural Genomics Consortium (SGC)
登録日2007-10-31
公開日2007-11-27
最終更新日2018-01-31
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural snapshots for the conformation-dependent catalysis by human medium-chain acyl-coenzyme A synthetase ACSM2A.
J.Mol.Biol., 388, 2009
3C5E
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CRYSTAL STRUCTURE OF HUMAN ACYL-COA SYNTHETASE MEDIUM-CHAIN FAMILY MEMBER 2A (L64P MUTATION) IN COMPLEX WITH ATP
分子名称:Acyl-coenzyme A synthetase ACSM2A, mitochondrial precursor, MAGNESIUM ION, ...
著者Pilka, E.S., Kochan, G.T., Bhatia, C., von Delft, F., Arrowsmith, C.H., Edwards, A.M., Weigelt, J., Bountra, C., Oppermann, U., Structural Genomics Consortium (SGC)
登録日2008-01-31
公開日2008-02-26
最終更新日2018-01-31
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structural snapshots for the conformation-dependent catalysis by human medium-chain acyl-coenzyme A synthetase ACSM2A.
J.Mol.Biol., 388, 2009
3DAY
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CRYSTAL STRUCTURE OF HUMAN ACYL-COA SYNTHETASE MEDIUM-CHAIN FAMILY MEMBER 2A (L64P MUTATION) IN COMPLEX WITH AMP-CPP
分子名称:Acyl-coenzyme A synthetase ACSM2A, mitochondrial precursor, MAGNESIUM ION, ...
著者Pilka, E.S., Kochan, G.T., Yue, W.W., Bhatia, C., von Delft, F., Arrowsmith, C.H., Edwards, A.M., Wikstrom, M., Bountra, C., Oppermann, U., Structural Genomics Consortium (SGC)
登録日2008-05-30
公開日2008-07-15
最終更新日2018-01-31
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Structural snapshots for the conformation-dependent catalysis by human medium-chain acyl-coenzyme A synthetase ACSM2A.
J.Mol.Biol., 388, 2009
3GPC
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CRYSTAL STRUCTURE OF HUMAN ACYL-COA SYNTHETASE MEDIUM-CHAIN FAMILY MEMBER 2A (L64P MUTATION) IN A COMPLEX WITH COA
分子名称:Acyl-coenzyme A synthetase ACSM2A, MAGNESIUM ION, COENZYME A
著者Pilka, E.S., Kochan, G.T., Yue, W.W., Bhatia, C., Von Delft, F., Arrowsmith, C.H., Edwards, A.M., Weigelt, J., Bountra, C., Oppermann, U., Structural Genomics Consortium (SGC)
登録日2009-03-23
公開日2009-04-07
最終更新日2017-11-01
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural snapshots for the conformation-dependent catalysis by human medium-chain acyl-coenzyme A synthetase ACSM2A
J.Mol.Biol., 388, 2009
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