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2WD9

CRYSTAL STRUCTURE OF HUMAN ACYL-COA SYNTHETASE MEDIUM-CHAIN FAMILY MEMBER 2A (L64P MUTATION) IN COMPLEX WITH IBUPROFEN

Summary for 2WD9
Entry DOI10.2210/pdb2wd9/pdb
Related2VZE
DescriptorACYL-COENZYME A SYNTHETASE ACSM2A, MITOCHONDRIAL, IBUPROFEN, MAGNESIUM ION, ... (4 entities in total)
Functional Keywordsnucleotide-binding, fatty acid metabolism, transit peptide, lipid metabolism, nucleotide binding, mitochondrion, metal-binding, ligase activity, medium-chain fatty acid, fatty acid metabolic process, ligase, magnesium, atp-binding
Biological sourceHOMO SAPIENS (HUMAN)
Total number of polymer chains3
Total formula weight190286.77
Authors
Yue, W.W.,Kochan, G.T.,Pilka, E.S.,Bhatia, C.,von Delft, F.,Arrowsmith, C.H.,Edwards, A.M.,Weigelt, J.,Bountra, C.,Oppermann, U. (deposition date: 2009-03-21, release date: 2009-04-21, Last modification date: 2023-12-13)
Primary citationKochan, G.,Pilka, E.S.,Delft, F.V.,Oppermann, U.,Yue, W.W.
Structural Snapshots for the Conformation- Dependent Catalysis by Human Medium-Chain Acyl- Coenzyme a Synthetase Acsm2A.
J.Mol.Biol., 388:997-, 2009
Cited by
PubMed: 19345228
DOI: 10.1016/J.JMB.2009.03.064
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.6 Å)
Structure validation

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