2YD0

Crystal structure of the soluble domain of human endoplasmic reticulum aminopeptidase 1 ERAP1

Replaces:  2XDT

Summary for 2YD0

• Entry DOI: 10.2210/pdb2yd0/pdb
• Descriptor: ENDOPLASMIC RETICULUM AMINOPEPTIDASE 1, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (8 entities in total)
• Functional Keywords: hydrolase, glycoprotein, metal-binding, metalloprotease, protease, adaptive immunity
• Biological source: HOMO SAPIENS (HUMAN)
• Total number of polymer chains: 1
• Total formula weight: 104180.06

Authors

Vollmar, M.,Kochan, G.,Krojer, T.,Ugochukwu, E.,Muniz, J.R.C.,Raynor, J.,Chaikuad, A.,Allerston, C.,von Delft, F.,Bountra, C.,Arrowsmith, C.H.,Weigelt, J.,Edwards, A.,Knapp, S. (deposition date: 2011-03-17, release date: 2011-04-13, Last modification date: 2020-07-29)

• Primary citation: Kochan, G.,Krojer, T.,Harvey, D.,Fischer, R.,Chen, L.,Vollmar, M.,von Delft, F.,Kavanagh, K.L.,Brown, M.A.,Bowness, P.,Wordsworth, P.,Kessler, B.M.,Oppermann, U.; Crystal Structures of the Endoplasmic Reticulum Aminopeptidase-1 (Erap1) Reveal the Molecular Basis for N-Terminal Peptide Trimming.; Proc.Natl.Acad.Sci.USA, 108:7745-, 2011; PubMed: 21508329; DOI: 10.1073/PNAS.1101262108

Experimental method

X-RAY DIFFRACTION (2.7 Å)