2YD0
Crystal structure of the soluble domain of human endoplasmic reticulum aminopeptidase 1 ERAP1
Replaces: 2XDTEntity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | ENDOPLASMIC RETICULUM AMINOPEPTIDASE 1 | polymer | 897 | 102596.0 | 1 | UniProt (Q9NZ08) Pfam (PF17900) Pfam (PF01433) Pfam (PF11838) In PDB | HOMO SAPIENS (HUMAN) | ADIPOCYTE-DERIVED LEUCINE AMINOPEPTIDASE, ARTS-1, AMINOPEPTIDASE PILS, PUROMYCIN-INSENSITIVE LEUCYL-SPECIFIC AMINOPEPTIDASE, TYPE 1 TUMOR NECROSIS FACTOR RECEPTOR SHEDDING AMINOPEPTIDASE REGULATOR, A-LAP, PILS-AP |
| 2 | B, C | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 2 | In PDB GlyTouCan (G42666HT) | |||
| 3 | A | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 1 | Chemie (NAG) | |||
| 4 | A | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 5 | A | POTASSIUM ION | non-polymer | 39.1 | 2 | Chemie (K) | |||
| 6 | A | 1,2-ETHANEDIOL | non-polymer | 62.1 | 1 | Chemie (EDO) | |||
| 7 | A | 2-(3-AMINO-2-HYDROXY-4-PHENYL-BUTYRYLAMINO)-4-METHYL-PENTANOIC ACID | non-polymer | 308.4 | 1 | Chemie (BES) | |||
| 8 | water | water | 18.0 | 288 | Chemie (HOH) |
Sequence modifications
A: 46 - 940 (UniProt: Q9NZ08)
| PDB | External Database | Details |
|---|---|---|
| Lys 941 | - | expression tag |
| Lys 942 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 102596.0 | |
| Branched | Number of molecules | 2 |
| Total formula weight | 848.8 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 735.3 | |
| All* | Total formula weight | 104180.1 |
