3BIC
Crystal structure of human methylmalonyl-CoA mutase
Summary for 3BIC
Entry DOI | 10.2210/pdb3bic/pdb |
Related | 1REQ |
Descriptor | Methylmalonyl-CoA mutase, mitochondrial precursor, CHLORIDE ION (3 entities in total) |
Functional Keywords | organic aciduria, methylmalonyl coa mutase deficiency, metabolic disease, structural genomics, structural genomics consortium, sgc, cobalamin, cobalt, disease mutation, isomerase, metal-binding, mitochondrion, transit peptide |
Biological source | Homo sapiens (human) |
Cellular location | Mitochondrion matrix: P22033 |
Total number of polymer chains | 2 |
Total formula weight | 169813.45 |
Authors | Ugochukwu, E.,Kochan, G.,Pantic, N.,Parizotto, E.,Pilka, E.S.,Pike, A.C.W.,Gileadi, O.,von Delft, F.,Arrowsmith, C.H.,Weigelt, J.,Edwards, A.M.,Oppermann, U.,Structural Genomics Consortium (SGC) (deposition date: 2007-11-30, release date: 2007-12-25, Last modification date: 2023-08-30) |
Primary citation | Froese, D.S.,Kochan, G.,Muniz, J.R.,Wu, X.,Gileadi, C.,Ugochukwu, E.,Krysztofinska, E.,Gravel, R.A.,Oppermann, U.,Yue, W.W. Structures of the human GTPase MMAA and vitamin B12-dependent methylmalonyl-CoA mutase and insight into their complex formation. J.Biol.Chem., 285:38204-38213, 2010 Cited by PubMed: 20876572DOI: 10.1074/jbc.M110.177717 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.6 Å) |
Structure validation
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