2XIQ
Crystal structure of human methylmalonyl-CoA mutase in complex with adenosylcobalamin and malonyl-CoA
Summary for 2XIQ
Entry DOI | 10.2210/pdb2xiq/pdb |
Related | 2XIJ |
Descriptor | METHYLMALONYL-COA MUTASE, MITOCHONDRIAL, COBALAMIN, 5'-DEOXYADENOSINE, ... (5 entities in total) |
Functional Keywords | organic aciduria, isomerase, metabolic disease, vitamin b12 |
Biological source | HOMO SAPIENS (HUMAN) |
Total number of polymer chains | 2 |
Total formula weight | 174542.00 |
Authors | Yue, W.W.,Froese, D.S.,Kochan, G.,Chaikuad, A.,Krojer, T.,Muniz, J.,Ugochukwu, E.,Arrowsmith, C.,Weigelt, J.,Edwards, A.,Bountra, C.,Oppermann, U. (deposition date: 2010-06-30, release date: 2010-09-29, Last modification date: 2023-12-20) |
Primary citation | Froese, D.S.,Kochan, G.,Muniz, J.,Wu, X.,Gileadi, C.,Ugochukwu, E.,Krysztofinska, E.,Gravel, R.A.,Oppermann, U.,Yue, W.W. Structures of the Human Gtpase Mmaa and Vitamin B12-Dependent Methylmalonyl-Coa Mutase and Insight Into Their Complex Formation. J.Biol.Chem., 285:38204-, 2010 Cited by PubMed: 20876572DOI: 10.1074/JBC.M110.177717 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.95 Å) |
Structure validation
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