Loading
PDBj
MenuPDBj@FacebookPDBj@X(formerly Twitter)PDBj@BlueSkyPDBj@YouTubewwPDB FoundationwwPDBDonate
RCSB PDBPDBeBMRBAdv. SearchSearch help
Search by PDB author
1VCA
DownloadVisualize
BU of 1vca by Molmil
CRYSTAL STRUCTURE OF AN INTEGRIN-BINDING FRAGMENT OF VASCULAR CELL ADHESION MOLECULE-1 AT 1.8 ANGSTROMS RESOLUTION
Descriptor: HUMAN VASCULAR CELL ADHESION MOLECULE-1
Authors:Jones, E.Y, Harlos, K, Bottomley, M.J, Robinson, R.C, Driscoll, P.C, Edwards, R.M, Clements, J.M, Dudgeon, T.J, Stuart, D.I.
Deposit date:1995-03-21
Release date:1995-09-15
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of an integrin-binding fragment of vascular cell adhesion molecule-1 at 1.8 A resolution.
Nature, 373, 1995
1HNG
DownloadVisualize
BU of 1hng by Molmil
CRYSTAL STRUCTURE AT 2.8 ANGSTROMS RESOLUTION OF A SOLUBLE FORM OF THE CELL ADHESION MOLECULE CD2
Descriptor: CD2
Authors:Jones, E.Y, Davis, S.J, Williams, A.F, Harlos, K, Stuart, D.I.
Deposit date:1994-08-10
Release date:1995-02-07
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structure at 2.8 A resolution of a soluble form of the cell adhesion molecule CD2.
Nature, 360, 1992
7B50
DownloadVisualize
BU of 7b50 by Molmil
Notum complex with ARUK3003778
Descriptor: 3-(3,4-dichlorophenyl)sulfanyl-1$l^{4},2,7,8-tetrazabicyclo[4.3.0]nona-1(6),2,4,7-tetraen-9-one, DIMETHYL SULFOXIDE, Palmitoleoyl-protein carboxylesterase NOTUM, ...
Authors:Jones, E.Y, Fish, P.
Deposit date:2020-12-03
Release date:2022-01-12
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (1.33 Å)
Cite:Virtual Screening Directly Identifies New Fragment-Sized Inhibitors of Carboxylesterase Notum with Nanomolar Activity.
J.Med.Chem., 65, 2022
7B4X
DownloadVisualize
BU of 7b4x by Molmil
Notum complex with ARUK3002697
Descriptor: 1,2-ETHANEDIOL, 6-(4-methylphenyl)sulfanyl-2~{H}-[1,2,4]triazolo[4,3-b]pyridazin-3-one, DIMETHYL SULFOXIDE, ...
Authors:Jones, E.Y, Fish, P.
Deposit date:2020-12-02
Release date:2022-01-12
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (1.24 Å)
Cite:Structural Analysis and Development of Notum Fragment Screening Hits.
Acs Chem Neurosci, 13, 2022
8S7C
DownloadVisualize
BU of 8s7c by Molmil
Ternary Complex of Cachd1, FZD5 and LRP6
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Frizzled-5, ...
Authors:Zhao, Y, Ren, J, Jones, E.Y.
Deposit date:2024-02-29
Release date:2024-04-24
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (4.7 Å)
Cite:Cachd1 interacts with Wnt receptors and regulates neuronal asymmetry in the zebrafish brain.
Science, 384, 2024
2V2W
DownloadVisualize
BU of 2v2w by Molmil
T CELL CROSS-REACTIVITY AND CONFORMATIONAL CHANGES DURING TCR ENGAGEMENT
Descriptor: BETA-2 MICROGLOBULIN, HIV P17, HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, ...
Authors:Lee, J.K, Stewart-Jones, G, Dong, T, Harlos, K, Di Gleria, K, Dorrell, L, Douek, D.C, Van Der Merwe, P.A, Jones, E.Y, Mcmichael, A.J.
Deposit date:2007-06-07
Release date:2007-11-06
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:T Cell Cross-Reactivity and Conformational Changes During Tcr Engagement.
J.Exp.Med., 200, 2004
2V2X
DownloadVisualize
BU of 2v2x by Molmil
T cell cross-reactivity and conformational changes during TCR engagement.
Descriptor: BETA-2 MICROGLOBULIN, HIV P17, HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, ...
Authors:Lee, J.K, Stewart-Jones, G, Dong, T, harlos, K, Di Gleria, K, Dorrell, L, Douek, D.C, van der Merwe, P.A, Jones, E.Y, McMichael, A.J.
Deposit date:2007-06-07
Release date:2007-11-06
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:T Cell Cross-Reactivity and Conformational Changes During Tcr Engagement.
J.Exp.Med., 200, 2004
6FKM
DownloadVisualize
BU of 6fkm by Molmil
Drosophila Plexin A in complex with Semaphorin 1b
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, MIP07328p, Plexin A, ...
Authors:Rozbesky, D, Harlos, K, Jones, E.Y.
Deposit date:2018-01-24
Release date:2019-02-06
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.96 Å)
Cite:Structural basis of semaphorin-plexin cis interaction.
Embo J., 2020
6TR5
DownloadVisualize
BU of 6tr5 by Molmil
Melatonin-Notum complex
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, DIMETHYL SULFOXIDE, N-[2-(5-methoxy-1H-indol-3-yl)ethyl]acetamide, ...
Authors:Zhao, Y, Jones, E.Y.
Deposit date:2019-12-17
Release date:2020-01-15
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (1.509 Å)
Cite:Structural characterization of melatonin as an inhibitor of the Wnt deacylase Notum.
J. Pineal Res., 68, 2020
6TR7
DownloadVisualize
BU of 6tr7 by Molmil
N-[2-(5-fluoro-1H-indol-3-yl)ethyl]acetamide-Notum complex
Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Palmitoleoyl-protein carboxylesterase NOTUM, ...
Authors:Zhao, Y, Jones, E.Y.
Deposit date:2019-12-17
Release date:2020-01-08
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (1.47 Å)
Cite:Structural characterization of melatonin as an inhibitor of the Wnt deacylase Notum.
J. Pineal Res., 68, 2020
6TR6
DownloadVisualize
BU of 6tr6 by Molmil
N-acetylserotonin-Notum complex
Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, DIMETHYL SULFOXIDE, ...
Authors:Zhao, Y, Jones, E.Y.
Deposit date:2019-12-17
Release date:2020-01-08
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:Structural characterization of melatonin as an inhibitor of the Wnt deacylase Notum.
J. Pineal Res., 68, 2020
3GJE
DownloadVisualize
BU of 3gje by Molmil
Rational development of high-affinity T-cell receptor-like antibodies
Descriptor: Fab Heavy Chain, Fab Light Chain
Authors:Stewart-Jones, G, Wadle, A, Hombach, A, Shenderov, E, Held, G, Fischer, E, Kleber, S, Stenner-Liewen, F, Bauer, S, McMichael, A, Knuth, A, Abken, H, Hombach, A.A, Cerundolo, V, Jones, E.Y, Renner, C.
Deposit date:2009-03-08
Release date:2009-04-28
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Rational development of high-affinity T-cell receptor-like antibodies
Proc.Natl.Acad.Sci.USA, 106, 2009
3GJF
DownloadVisualize
BU of 3gjf by Molmil
Rational development of high-affinity T-cell receptor-like antibodies
Descriptor: Antibody heavy chain, Antibody light chain, Beta-2-microglobulin, ...
Authors:Stewart-Jones, G, Wadle, A, Hombach, A, Shenderov, E, Held, G, Fischer, E, Kleber, S, Stenner-Liewen, F, Bauer, S, McMichael, A, Knuth, A, Abken, H, Hombach, A.A, Cerundolo, V, Jones, E.Y, Renner, C.
Deposit date:2009-03-08
Release date:2009-04-28
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Rational development of high-affinity T-cell receptor-like antibodies
Proc.Natl.Acad.Sci.USA, 106, 2009
3GIV
DownloadVisualize
BU of 3giv by Molmil
Antigen processing influences HIV-specific cytotoxic T lymphocyte immunodominance
Descriptor: Beta-2-microglobulin, HIV-1 peptide, HLA class I histocompatibility antigen, ...
Authors:Stewart-Jones, G, Iversen, A.K.N, Jones, E.Y.
Deposit date:2009-03-06
Release date:2009-06-30
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2 Å)
Cite:Antigen processing influences HIV-specific cytotoxic T lymphocyte immunodominance
Nat.Immunol., 10, 2009
4WBH
DownloadVisualize
BU of 4wbh by Molmil
STRUCTURE OF THE WNT DEACYLASE NOTUM - CRYSTAL FORM I APO - 2.2A
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, Protein notum homolog, ...
Authors:Zebisch, M, Jones, E.Y.
Deposit date:2014-09-03
Release date:2015-02-25
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Notum deacylates Wnt proteins to suppress signalling activity
Nature, 519, 2015
4V2E
DownloadVisualize
BU of 4v2e by Molmil
FLRT3 LRR domain
Descriptor: FIBRONECTIN LEUCINE RICH TRANSMEMBRANE PROTEIN 3
Authors:Seiradake, E, del Toro, D, Nagel, D, Cop, F, Haertl, R, Ruff, T, Seyit-Bremer, G, Harlos, K, Border, E.C, Acker-Palmer, A, Jones, E.Y, Klein, R.
Deposit date:2014-10-08
Release date:2014-11-05
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Flrt Structure: Balancing Repulsion and Cell Adhesion in Cortical and Vascular Development.
Neuron, 84, 2014
4V2D
DownloadVisualize
BU of 4v2d by Molmil
FLRT2 LRR domain
Descriptor: FIBRONECTIN LEUCINE RICH TRANSMEMBRANE PROTEIN 2
Authors:Seiradake, E, del Toro, D, Nagel, D, Cop, F, Haertl, R, Ruff, T, Seyit-Bremer, G, Harlos, K, Border, E.C, Acker-Palmer, A, Jones, E.Y, Klein, R.
Deposit date:2014-10-08
Release date:2014-11-05
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Flrt Structure: Balancing Repulsion and Cell Adhesion in Cortical and Vascular Development
Neuron, 84, 2014
4V2B
DownloadVisualize
BU of 4v2b by Molmil
rat Unc5D Ig domain 1
Descriptor: PROTEIN UNC5D
Authors:Seiradake, E, del Toro, D, Nagel, D, Cop, F, Haertl, R, Ruff, T, Seyit-Bremer, G, Harlos, K, Border, E.C, Acker-Palmer, A, Jones, E.Y, Klein, R.
Deposit date:2014-10-08
Release date:2014-11-05
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (2 Å)
Cite:Flrt Structure: Balancing Repulsion and Cell Adhesion in Cortical and Vascular Development
Neuron, 84, 2014
4UZ7
DownloadVisualize
BU of 4uz7 by Molmil
STRUCTURE OF THE WNT DEACYLASE NOTUM - CRYSTAL FORM VI - 2.2A
Descriptor: CHLORIDE ION, PROTEIN NOTUM HOMOLOG
Authors:Zebisch, M, Jones, E.Y.
Deposit date:2014-09-04
Release date:2015-02-25
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Notum Deacylates Wnt Proteins to Suppress Signalling Activity.
Nature, 519, 2015
2V5Y
DownloadVisualize
BU of 2v5y by Molmil
Crystal structure of the receptor protein tyrosine phosphatase mu ectodomain
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE MU, SODIUM ION
Authors:Aricescu, A.R, Siebold, C, Choudhuri, K, Chang, V.T, Lu, W, Davis, S.J, van der Merwe, P.A, Jones, E.Y.
Deposit date:2007-07-11
Release date:2007-09-11
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structure of a Tyrosine Phosphatase Adhesive Interaction Reveals a Spacer-Clamp Mechanism.
Science, 317, 2007
2V5N
DownloadVisualize
BU of 2v5n by Molmil
STRUCTURE OF HUMAN IGF2R DOMAINS 11-12
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CATION-INDEPENDENT MANNOSE-6-PHOSPHATE RECEPTOR
Authors:Brown, J, Delaine, C, Zaccheo, O.J, Siebold, C, Gilbert, R.J, van Boxel, G, Denley, A, Wallace, J.C, Hassan, A.B, Forbes, B.E, Jones, E.Y.
Deposit date:2007-07-06
Release date:2007-12-11
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structure and Functional Analysis of the Igf-II/Igf2R Interaction
Embo J., 27, 2008
2V5O
DownloadVisualize
BU of 2v5o by Molmil
STRUCTURE OF HUMAN IGF2R DOMAINS 11-14
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CATION-INDEPENDENT MANNOSE-6-PHOSPHATE RECEPTOR, CHLORIDE ION
Authors:Brown, J, Delaine, C, Zaccheo, O.J, Siebold, C, Gilbert, R.J, van Boxel, G, Denley, A, Wallace, J.C, Hassan, A.B, Forbes, B.E, Jones, E.Y.
Deposit date:2007-07-06
Release date:2007-12-11
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (2.91 Å)
Cite:Structure and Functional Analysis of the Igf-II/Igf2R Interaction
Embo J., 27, 2008
2YPL
DownloadVisualize
BU of 2ypl by Molmil
Structural features underlying T-cell receptor sensitivity to concealed MHC class I micropolymorphisms
Descriptor: AGA T-CELL RECEPTOR ALPHA CHAIN, AGA T-CELL RECEPTOR BETA CHAIN, BETA-2-MICROGLOBULIN, ...
Authors:Stewart-Jones, G.B, Simpson, P, van der Merwe, P.A, Easterbrook, P, McMichael, A.J, Rowland-Jones, S.L, Jones, E.Y, Gillespie, G.M.
Deposit date:2012-10-30
Release date:2012-11-28
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural Features Underlying T-Cell Receptor Sensitivity to Concealed Mhc Class I Micropolymorphisms.
Proc.Natl.Acad.Sci.USA, 109, 2012
4UFR
DownloadVisualize
BU of 4ufr by Molmil
Structure of the ectodomain of LGR5 in complex with R-spondin-2 (Fu1Fu2)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, LEUCINE-RICH REPEAT-CONTAINING G-PROTEIN COUPLED RECEPTOR 5, ...
Authors:Zebisch, M, Jones, E.Y.
Deposit date:2015-03-18
Release date:2015-07-08
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal Structure of R-Spondin 2 in Complex with the Ectodomains of its Receptors Lgr5 and Znrf3.
J.Struct.Biol., 191, 2015
4UZ1
DownloadVisualize
BU of 4uz1 by Molmil
STRUCTURE OF THE WNT DEACYLASE NOTUM - CRYSTAL FORM III - 1.4A
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, NOTUM, SULFATE ION
Authors:Zebisch, M, Jones, E.Y.
Deposit date:2014-09-04
Release date:2015-02-25
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Notum Deacylates Wnt Proteins to Suppress Signalling Activity.
Nature, 519, 2015

238582

PDB entries from 2025-07-09

PDB statisticsPDBj update infoContact PDBjnumon