2YPL

Structural features underlying T-cell receptor sensitivity to concealed MHC class I micropolymorphisms

Summary for 2YPL

Entry DOI	10.2210/pdb2ypl/pdb
Related	2YPK
Descriptor	HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, B-57 ALPHA CHAIN, BETA-2-MICROGLOBULIN, KF11 P24 GAG PEPTIDE, ... (6 entities in total)
Functional Keywords	immune system-viral protein complex, micropolymorphism, immune system/viral protein
Biological source	HOMO SAPIENS (HUMAN) More
Cellular location	Membrane; Single-pass type I membrane protein: P18465 Secreted: P61769
Total number of polymer chains	5
Total formula weight	93725.50
Authors	Stewart-Jones, G.B.,Simpson, P.,van der Merwe, P.A.,Easterbrook, P.,McMichael, A.J.,Rowland-Jones, S.L.,Jones, E.Y.,Gillespie, G.M. (deposition date: 2012-10-30, release date: 2012-11-28, Last modification date: 2023-12-20)
Primary citation	Stewart-Jones, G.B.,Simpson, P.,Anton Van Der Merwe, P.,Easterbrook, P.,Mcmichael, A.J.,Rowland-Jones, S.L.,Jones, E.Y.,Gillespie, G.M. Structural Features Underlying T-Cell Receptor Sensitivity to Concealed Mhc Class I Micropolymorphisms. Proc.Natl.Acad.Sci.USA, 109:E3483-, 2012 Cited by PubMed: 23161907 DOI: 10.1073/PNAS.1207896109 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.4 Å)

Structure validation