6TR7

N-[2-(5-fluoro-1H-indol-3-yl)ethyl]acetamide-Notum complex

Summary for 6TR7

Entry DOI	10.2210/pdb6tr7/pdb
Descriptor	Palmitoleoyl-protein carboxylesterase NOTUM, SULFATE ION, 1,2-ETHANEDIOL, ... (6 entities in total)
Functional Keywords	wnt receptor frizzled8 carbamazepine, oncoprotein
Biological source	Homo sapiens (Human)
Total number of polymer chains	1
Total formula weight	45550.04
Authors	Zhao, Y.,Jones, E.Y. (deposition date: 2019-12-17, release date: 2020-01-08, Last modification date: 2024-01-24)
Primary citation	Zhao, Y.,Ren, J.,Hillier, J.,Jones, M.,Lu, W.,Jones, E.Y. Structural characterization of melatonin as an inhibitor of the Wnt deacylase Notum. J. Pineal Res., 68:e12630-e12630, 2020 Cited by PubMed: 31876313 DOI: 10.1111/jpi.12630 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.47 Å)

Structure validation