6TR6

N-acetylserotonin-Notum complex

Summary for 6TR6

Entry DOI	10.2210/pdb6tr6/pdb
Descriptor	Palmitoleoyl-protein carboxylesterase NOTUM, 2-acetamido-2-deoxy-beta-D-glucopyranose, SULFATE ION, ... (7 entities in total)
Functional Keywords	wnt notum inhibitor, oncoprotein
Biological source	Homo sapiens (Human)
Total number of polymer chains	1
Total formula weight	45045.78
Authors	Zhao, Y.,Jones, E.Y. (deposition date: 2019-12-17, release date: 2020-01-08, Last modification date: 2024-01-24)
Primary citation	Zhao, Y.,Ren, J.,Hillier, J.,Jones, M.,Lu, W.,Jones, E.Y. Structural characterization of melatonin as an inhibitor of the Wnt deacylase Notum. J. Pineal Res., 68:e12630-e12630, 2020 Cited by PubMed: 31876313 DOI: 10.1111/jpi.12630 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.35 Å)

Structure validation