Author results

4AY9
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STRUCTURE OF FOLLICLE-STIMULATING HORMONE IN COMPLEX WITH THE ENTIRE ECTODOMAIN OF ITS RECEPTOR
Descriptor:GLYCOPROTEIN HORMONES, ALPHA POLYPEPTIDE, FOLLITROPIN SUBUNIT BETA, ...
Authors:Jiang, X., Liu, H., Chen, X., He, X.
Deposit date:2012-06-19
Release date:2012-08-08
Last modified:2012-08-15
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structure of Follicle-Stimulating Hormone in Complex with the Entire Ectodomain of its Receptor.
Proc.Natl.Acad.Sci.USA, 109, 2012
4MQW
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STRUCTURE OF FOLLICLE-STIMULATING HORMONE IN COMPLEX WITH THE ENTIRE ECTODOMAIN OF ITS RECEPTOR (P31)
Descriptor:Glycoprotein hormones, alpha polypeptide, Follitropin subunit beta, ...
Authors:Jiang, X., Liu, H., Chen, X., He, X.
Deposit date:2013-09-16
Release date:2014-04-09
Last modified:2014-09-24
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Evidence for Follicle-stimulating Hormone Receptor as a Functional Trimer.
J.Biol.Chem., 289, 2014
1GKO
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AN ENGINEERED TRANSTHYRETIN MONOMER THAT IS NON-AMYLOIDOGENIC - UNLESS PARTIALLY DENATURED
Descriptor:TRANSTHYRETIN
Authors:Jiang, X., Smith, C.S., Petrassi, H.M., Hammarstrom, P., White, J.T., Sacchettini, J.C., Kelly, J.W.
Deposit date:2001-08-17
Release date:2001-11-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:An Engineered Transthyretin Monomer that is Nonamyloidogenic, Unless It is Partially Denatured
Biochemistry, 40, 2001
1SCF
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HUMAN RECOMBINANT STEM CELL FACTOR
Descriptor:STEM CELL FACTOR, PENTAETHYLENE GLYCOL, CALCIUM ION
Authors:Jiang, X., Gurel, O., Langley, K.E., Hendrickson, W.A.
Deposit date:1998-06-04
Release date:2000-07-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure of the active core of human stem cell factor and analysis of binding to its receptor kit.
EMBO J., 19, 2000
3WZF
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CRYSTAL STRUCTURE OF HUMAN CYTOPLASMIC ASPARTATE AMINOTRANSFERASE
Descriptor:Aspartate aminotransferase, cytoplasmic
Authors:Jiang, X., Chang, H., Zhou, Y., Chen, L., Yang, Q.
Deposit date:2014-09-24
Release date:2015-10-07
Method:X-RAY DIFFRACTION (2.991 Å)
Cite:Recombinant expression, purification and Preliminary crystallographic studies of human cytoplasmic aspartate aminotransferase
To be Published
4G9Z
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LASSA NUCLEOPROTEIN WITH DSRNA REVEALS NOVEL MECHANISM FOR IMMUNE SUPPRESSION
Descriptor:RNA (5'-R(P*GP*CP*CP*C)-3'), RNA (5'-R(P*GP*GP*GP*C)-3'), Nucleoprotein, ...
Authors:Jiang, X., Huang, Q., Wang, W., Dong, H., Ly, H., Liang, Y., Dong, C., Scottish Structural Proteomics Facility (SSPF)
Deposit date:2012-07-24
Release date:2013-04-03
Last modified:2013-07-24
Method:X-RAY DIFFRACTION (2.03 Å)
Cite:Structures of Arenaviral Nucleoproteins with Triphosphate dsRNA Reveal a Unique Mechanism of Immune Suppression.
J.Biol.Chem., 288, 2013
4GV3
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STRUCTURES OF LASSA AND TACARIBE VIRAL NUCLEOPROTEINS WITH OR WITHOUT 5 TRIPHOSPHATE DSRNA SUBSTRATE REVEAL A UNIQUE 3 -5 EXORIBONUCLEASE MECHANISM TO SUPPRESS TYPE I INTERFERON PRODUCTION
Descriptor:RNA (5'-R(*(GTP)P*GP*GP*C)-3'), RNA (5'-R(P*CP*GP*CP*CP*C)-3'), Nucleoprotein, ...
Authors:Jiang, X., Huang, Q., Wang, W., Dong, H., Ly, H., Liang, Y., Dong, C.
Deposit date:2012-08-30
Release date:2013-05-01
Last modified:2013-07-10
Method:X-RAY DIFFRACTION (1.68 Å)
Cite:Structures of Arenaviral Nucleoproteins with Triphosphate dsRNA Reveal a Unique Mechanism of Immune Suppression.
J.Biol.Chem., 288, 2013
4GV6
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STRUCTURES OF LASSA AND TACARIBE VIRAL NUCLEOPROTEINS WITH OR WITHOUT 5 TRIPHOSPHATE DSRNA SUBSTRATE REVEAL A UNIQUE 3 -5 EXORIBONUCLEASE MECHANISM TO SUPPRESS TYPE I INTERFERON PRODUCTION
Descriptor:RNA (5'-R(*(GTP)P*GP*GP*C)-3'), RNA (5'-R(P*CP*GP*CP*CP*C)-3'), Nucleoprotein, ...
Authors:Jiang, X., Huang, Q., Wang, W., Dong, H., Ly, H., Liang, Y., Dong, C.
Deposit date:2012-08-30
Release date:2013-05-01
Last modified:2013-07-10
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:Structures of Arenaviral Nucleoproteins with Triphosphate dsRNA Reveal a Unique Mechanism of Immune Suppression.
J.Biol.Chem., 288, 2013
4GV9
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LASSA NUCLEOPROTEIN C-TERMINAL DOMAIN IN COMPLEX WITH TRIPHOSPHATED DSRNA SOAKING FOR 5 MIN
Descriptor:RNA (5'-R(*(GTP)P*GP*GP*C)-3'), RNA (5'-R(P*CP*GP*CP*CP*C)-3'), Nucleoprotein, ...
Authors:Jiang, X., Huang, Q., Wang, W., Dong, H., Ly, H., Liang, Y., Dong, C.
Deposit date:2012-08-30
Release date:2013-05-01
Last modified:2013-07-10
Method:X-RAY DIFFRACTION (2.46 Å)
Cite:Structures of Arenaviral Nucleoproteins with Triphosphate dsRNA Reveal a Unique Mechanism of Immune Suppression.
J.Biol.Chem., 288, 2013
4GVE
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TACARIBE NUCLEOPROTEIN STRUCTURE
Descriptor:Nucleoprotein, ZINC ION, MAGNESIUM ION
Authors:Jiang, X., Huang, Q., Wang, W., Dong, H., Ly, H., Liang, Y., Dong, C.
Deposit date:2012-08-30
Release date:2013-05-01
Last modified:2013-07-10
Method:X-RAY DIFFRACTION (1.73 Å)
Cite:Structures of Arenaviral Nucleoproteins with Triphosphate dsRNA Reveal a Unique Mechanism of Immune Suppression.
J.Biol.Chem., 288, 2013
5AX8
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RECOMBINANT EXPRESSION, PURIFICATION AND PRELIMINARY CRYSTALLOGRAPHIC STUDIES OF THE MATURE FORM OF HUMAN MITOCHONDRIAL ASPARTATE AMINOTRANSFERASE
Descriptor:Aspartate aminotransferase, mitochondrial
Authors:Jiang, X., Wang, J., Chang, H., Zhou, Y.
Deposit date:2015-07-20
Release date:2016-03-16
Last modified:2016-04-06
Method:X-RAY DIFFRACTION (2.989 Å)
Cite:Recombinant expression, purification and crystallographic studies of the mature form of human mitochondrial aspartate aminotransferase
Biosci Trends, 10, 2016
5GXB
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CRYSTAL STRUCTURE OF A LACY/NANOBODY COMPLEX
Descriptor:Lactose permease, nanobody
Authors:Jiang, X., Wu, J.P., Yan, N., Kaback, H.R.
Deposit date:2016-09-16
Release date:2016-10-26
Last modified:2017-09-20
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Crystal structure of a LacY-nanobody complex in a periplasmic-open conformation.
Proc.Natl.Acad.Sci.USA, 113, 2016
5WYP
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CRYSTAL STRUCTURE OF DNA POLYMERASE SLIDING CLAMP FROM CAULOBACTER CRESCENTUS
Descriptor:DNA polymerase III subunit beta
Authors:Jiang, X., Zhang, L., Teng, M., Li, X.
Deposit date:2017-01-15
Release date:2018-03-21
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of DNA polymerase sliding clamp from Caulobacter crescentus
To Be Published
4JAI
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CRYSTAL STRUCTURE OF AURORA KINASE A IN COMPLEX WITH N-{4-[(6-OXO-5,6-DIHYDROBENZO[C][1,8]NAPHTHYRIDIN-1-YL)AMINO]PHENYL}BENZAMIDE
Descriptor:Aurora kinase A, N-{4-[(6-oxo-5,6-dihydrobenzo[c][1,8]naphthyridin-1-yl)amino]phenyl}benzamide
Authors:Jiang, X., Josephson, K., Huck, B., Goutopoulos, A., Karra, S.
Deposit date:2013-02-18
Release date:2013-05-22
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:SAR and evaluation of novel 5H-benzo[c][1,8]naphthyridin-6-one analogs as Aurora kinase inhibitors.
Bioorg.Med.Chem.Lett., 23, 2013
4JAJ
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CRYSTAL STRUCTURE OF AURORA KINASE A IN COMPLEX WITH BENZO[C][1,8]NAPHTHYRIDIN-6(5H)-ONE
Descriptor:Aurora kinase A, benzo[c][1,8]naphthyridin-6(5H)-one
Authors:Jiang, X., Josephson, K., Huck, B., Goutopoulos, A., Karra, S.
Deposit date:2013-02-18
Release date:2013-05-22
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:SAR and evaluation of novel 5H-benzo[c][1,8]naphthyridin-6-one analogs as Aurora kinase inhibitors.
Bioorg.Med.Chem.Lett., 23, 2013
2GU0
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CRYSTAL STRUCTURE OF HUMAN ROTAVIRUS NSP2 (GROUP C / BRISTOL STRAIN)
Descriptor:Nonstructural protein 2
Authors:Jiang, X., Prasad, B.V.V.
Deposit date:2006-04-28
Release date:2006-09-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structure-function analysis of rotavirus NSP2 octamer by using a novel complementation system
J.Virol., 80, 2006
4NKI
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CRYSTAL STRUCTURE OF A FAB
Descriptor:Fab light chain, Fab heavy chain, 1,2-ETHANEDIOL
Authors:Jiang, X.
Deposit date:2013-11-12
Release date:2014-11-12
Last modified:2015-04-22
Method:X-RAY DIFFRACTION (2.41 Å)
Cite:Epitope characterization of an anti-PD-L1 antibody using orthogonal approaches.
J.Mol.Recognit., 28, 2015
5WZZ
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THE SIAH E3 UBIQUITIN LIGASES PROMOTE WNT/ BETA-CATENIN SIGNALING THROUGH MEDIATING WNT-INDUCED AXIN DEGRADATION
Descriptor:E3 ubiquitin-protein ligase SIAH1, Axin-1, ZINC ION
Authors:Ji, L., Jiang, B., Jiang, X., Charlat, O., Chen, A., Mickanin, C., Bauer, A., Xu, W., Yan, X.-X., Cong, F.
Deposit date:2017-01-19
Release date:2017-08-16
Last modified:2017-08-30
Method:X-RAY DIFFRACTION (2.103 Å)
Cite:The SIAH E3 ubiquitin ligases promote Wnt/ beta-catenin signaling through mediating Wnt-induced Axin degradation
Genes Dev., 31, 2017
2LIR
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NMR SOLUTION STRUCTURE OF YEAST ISO-1-CYTOCHROME C MUTANT P71H IN OXIDIZED STATES
Descriptor:Cytochrome c iso-1, HEME C
Authors:Lan, W., Wang, Z., Yang, Z., Zhu, J., Ying, T., Jiang, X., Zhang, X., Wu, H., Liu, M., Tan, X., Cao, C., Huang, Z.X.
Deposit date:2011-08-31
Release date:2011-12-07
Method:SOLUTION NMR
Cite:Conformational toggling of yeast iso-1-cytochrome C in the oxidized and reduced States.
Plos One, 6, 2011
2LIT
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NMR SOLUTION STRUCTURE OF YEAST ISO-1-CYTOCHROME C MUTANT P71H IN REDUCED STATES
Descriptor:Cytochrome c iso-1, HEME C
Authors:Lan, W., Wang, Z., Yang, Z., Zhu, J., Ying, T., Jiang, X., Zhang, X., Wu, H., Liu, M., Tan, X., Cao, C., Huang, Z.X.
Deposit date:2011-08-31
Release date:2011-12-07
Method:SOLUTION NMR
Cite:Conformational toggling of yeast iso-1-cytochrome C in the oxidized and reduced States.
Plos One, 6, 2011
5EQJ
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CRYSTAL STRUCTURE OF THE TWO-SUBUNIT TRNA M1A58 METHYLTRANSFERASE FROM SACCHAROMYCES CEREVISIAE
Descriptor:tRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit TRM6, tRNA (adenine(58)-N(1))-methyltransferase catalytic subunit TRM61
Authors:Zhu, Y., Wang, M., Wang, C., Fan, X., Jiang, X., Teng, M., Li, X.
Deposit date:2015-11-13
Release date:2016-09-14
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of the two-subunit tRNA m(1)A58 methyltransferase TRM6-TRM61 from Saccharomyces cerevisiae.
Sci Rep, 6, 2016
5ERG
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CRYSTAL STRUCTURE OF THE TWO-SUBUNIT TRNA M1A58 METHYLTRANSFERASE TRM6-TRM61 IN COMPLEX WITH SAM
Descriptor:tRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit TRM6, tRNA (adenine(58)-N(1))-methyltransferase catalytic subunit TRM61, S-ADENOSYLMETHIONINE
Authors:Zhu, Y., Wang, M., Wang, C., Fan, X., Jiang, X., Teng, M., Li, X.
Deposit date:2015-11-14
Release date:2016-09-14
Method:X-RAY DIFFRACTION (2.202 Å)
Cite:Crystal structure of the two-subunit tRNA m(1)A58 methyltransferase TRM6-TRM61 from Saccharomyces cerevisiae.
Sci Rep, 6, 2016
4RDJ
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CRYSTAL STRUCTURE OF NOROVIRUS BOXER P DOMAIN
Descriptor:Capsid
Authors:Hao, N., Chen, Y., Xia, M., Liu, W., Tan, M., Jiang, X., Li, X.
Deposit date:2014-09-19
Release date:2015-01-14
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Crystal structures of GI.8 Boxer virus P dimers in complex with HBGAs, a novel evolutionary path selected by the Lewis epitope
Protein Cell, 2014
4RDK
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CRYSTAL STRUCTURE OF NOROVIRUS BOXER P DOMAIN IN COMPLEX WITH LEWIS B TETRASACCHARIDE
Descriptor:Capsid, ALPHA-L-FUCOSE, 2-(ACETYLAMINO)-2-DEOXY-A-D-GLUCOPYRANOSE, ...
Authors:Hao, N., Chen, Y., Xia, M., Liu, W., Tan, M., Jiang, X., Li, X.
Deposit date:2014-09-19
Release date:2015-01-14
Method:X-RAY DIFFRACTION (1.629 Å)
Cite:Crystal structures of GI.8 Boxer virus P dimers in complex with HBGAs, a novel evolutionary path selected by the Lewis epitope
Protein Cell, 2014
4RDL
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CRYSTAL STRUCTURE OF NOROVIRUS BOXER P DOMAIN IN COMPLEX WITH LEWIS Y TETRASACCHARIDE
Descriptor:Capsid, ALPHA-L-FUCOSE, BETA-D-GALACTOSE, ...
Authors:Hao, N., Chen, Y., Xia, M., Liu, W., Tan, M., Jiang, X., Li, X.
Deposit date:2014-09-19
Release date:2015-01-14
Method:X-RAY DIFFRACTION (1.449 Å)
Cite:Crystal structures of GI.8 Boxer virus P dimers in complex with HBGAs, a novel evolutionary path selected by the Lewis epitope
Protein Cell, 2014
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