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3L6Y
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BU of 3l6y by Molmil
Crystal structure of p120 catenin in complex with E-cadherin
Descriptor: Catenin delta-1, E-cadherin
Authors:Ishiyama, N, Lee, S.-H, Liu, S, Li, G.-Y, Smith, M.J, Reichardt, L.F, Ikura, M.
Deposit date:2009-12-27
Release date:2010-04-21
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (3 Å)
Cite:Dynamic and static interactions between p120 catenin and E-cadherin regulate the stability of cell-cell adhesion.
Cell(Cambridge,Mass.), 141, 2010
3L6X
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BU of 3l6x by Molmil
Crystal structure of p120 catenin in complex with E-cadherin
Descriptor: Catenin delta-1, E-cadherin, SULFATE ION
Authors:Ishiyama, N, Lee, S.-H, Liu, S, Li, G.-Y, Smith, M.J, Reichardt, L.F, Ikura, M.
Deposit date:2009-12-27
Release date:2010-04-21
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Dynamic and static interactions between p120 catenin and E-cadherin regulate the stability of cell-cell adhesion.
Cell(Cambridge,Mass.), 141, 2010
4K1O
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BU of 4k1o by Molmil
Crystal structure of the alphaN-catenin actin-binding domain
Descriptor: Catenin alpha-2, SULFATE ION
Authors:Ishiyama, N, Ikura, M.
Deposit date:2013-04-05
Release date:2013-05-01
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.603 Å)
Cite:An autoinhibited structure of alpha-catenin and its implications for vinculin recruitment to adherens junctions.
J.Biol.Chem., 288, 2013
4K1N
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BU of 4k1n by Molmil
Crystal structure of full-length mouse alphaE-catenin
Descriptor: Catenin alpha-1
Authors:Ishiyama, N, Ikura, M.
Deposit date:2013-04-05
Release date:2013-05-01
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (6.5 Å)
Cite:An autoinhibited structure of alpha-catenin and its implications for vinculin recruitment to adherens junctions.
J.Biol.Chem., 288, 2013
1SB9
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BU of 1sb9 by Molmil
Crystal structure of Pseudomonas aeruginosa UDP-N-acetylglucosamine 4-epimerase complexed with UDP-glucose
Descriptor: NICOTINAMIDE-ADENINE-DINUCLEOTIDE, URIDINE-5'-DIPHOSPHATE-GLUCOSE, wbpP
Authors:Ishiyama, N, Creuzenet, C, Lam, J.S, Berghuis, A.M.
Deposit date:2004-02-10
Release date:2004-05-25
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal Structure of WbpP, a Genuine UDP-N-acetylglucosamine 4-Epimerase from Pseudomonas aeruginosa: SUBSTRATE SPECIFICITY IN UDP-HEXOSE 4-EPIMERASES.
J.Biol.Chem., 279, 2004
1SB8
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BU of 1sb8 by Molmil
Crystal structure of Pseudomonas aeruginosa UDP-N-acetylglucosamine 4-epimerase complexed with UDP-N-acetylgalactosamine
Descriptor: NICOTINAMIDE-ADENINE-DINUCLEOTIDE, URIDINE-DIPHOSPHATE-N-ACETYLGALACTOSAMINE, wbpP
Authors:Ishiyama, N, Creuzenet, C, Lam, J.S, Berghuis, A.M.
Deposit date:2004-02-10
Release date:2004-05-25
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal Structure of WbpP, a Genuine UDP-N-acetylglucosamine 4-Epimerase from Pseudomonas aeruginosa: SUBSTRATE SPECIFICITY IN UDP-HEXOSE 4-EPIMERASES.
J.Biol.Chem., 279, 2004
6DUY
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BU of 6duy by Molmil
Crystal structure of the alpha-N-catenin actin-binding domain H1 mutant
Descriptor: Catenin alpha-2
Authors:Ishiyama, N, Ikura, M.
Deposit date:2018-06-22
Release date:2018-12-19
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.81 Å)
Cite:Force-dependent allostery of the alpha-catenin actin-binding domain controls adherens junction dynamics and functions.
Nat Commun, 9, 2018
6DUW
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BU of 6duw by Molmil
Crystal structure of the alpha-N-catenin actin-binding domain H1 mutant
Descriptor: Catenin alpha-2
Authors:Ishiyama, N, Ikura, M.
Deposit date:2018-06-22
Release date:2018-12-19
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Force-dependent allostery of the alpha-catenin actin-binding domain controls adherens junction dynamics and functions.
Nat Commun, 9, 2018
6DV1
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BU of 6dv1 by Molmil
Crystal structure of the alpha-E-catenin actin-binding domain
Descriptor: BROMIDE ION, Catenin alpha-1, SULFATE ION
Authors:Ishiyama, N, Ikura, M.
Deposit date:2018-06-22
Release date:2018-12-19
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Force-dependent allostery of the alpha-catenin actin-binding domain controls adherens junction dynamics and functions.
Nat Commun, 9, 2018
2GNA
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BU of 2gna by Molmil
Crystal structure of UDP-GlcNAc inverting 4,6-dehydratase in complex with NADP and UDP-Gal
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, GALACTOSE-URIDINE-5'-DIPHOSPHATE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
Authors:Ishiyama, N, Creuzenet, C, Lam, J.S, Berghuis, A.M.
Deposit date:2006-04-09
Release date:2006-05-09
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural Studies of FlaA1 from Helicobacter pylori Reveal the Mechanism for Inverting 4,6-Dehydratase Activity.
J.Biol.Chem., 281, 2006
2GN8
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Crystal structure of UDP-GlcNAc inverting 4,6-dehydratase in complex with NADP and UDP
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, UDP-GlcNAc C6 dehydratase, ...
Authors:Ishiyama, N, Creuzenet, C, Lam, J.S, Berghuis, A.M.
Deposit date:2006-04-09
Release date:2006-05-09
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural Studies of FlaA1 from Helicobacter pylori Reveal the Mechanism for Inverting 4,6-Dehydratase Activity.
J.Biol.Chem., 281, 2006
2GN6
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BU of 2gn6 by Molmil
Crystal structure of UDP-GlcNAc inverting 4,6-dehydratase in complex with NADP and UDP-GlcNAc
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, UDP-GlcNAc C6 dehydratase, ...
Authors:Ishiyama, N, Creuzenet, C, Lam, J.S, Berghuis, A.M.
Deposit date:2006-04-09
Release date:2006-05-09
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural Studies of FlaA1 from Helicobacter pylori Reveal the Mechanism for Inverting 4,6-Dehydratase Activity.
J.Biol.Chem., 281, 2006
2GN9
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BU of 2gn9 by Molmil
Crystal structure of UDP-GlcNAc inverting 4,6-dehydratase in complex with NADP and UDP-Glc
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, UDP-GlcNAc C6 dehydratase, ...
Authors:Ishiyama, N, Creuzenet, C, Lam, J.S, Berghuis, A.M.
Deposit date:2006-04-09
Release date:2006-05-09
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural Studies of FlaA1 from Helicobacter pylori Reveal the Mechanism for Inverting 4,6-Dehydratase Activity.
J.Biol.Chem., 281, 2006
2GN4
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BU of 2gn4 by Molmil
Crystal structure of UDP-GlcNAc inverting 4,6-dehydratase in complex with NADPH and UDP-GlcNAc
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, UDP-GlcNAc C6 dehydratase, ...
Authors:Ishiyama, N, Creuzenet, C, Lam, J.S, Berghuis, A.M.
Deposit date:2006-04-09
Release date:2006-05-09
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural Studies of FlaA1 from Helicobacter pylori Reveal the Mechanism for Inverting 4,6-Dehydratase Activity.
J.Biol.Chem., 281, 2006
6OS4
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BU of 6os4 by Molmil
Calmodulin in complex with farnesyl cysteine methyl ester
Descriptor: CALCIUM ION, Calmodulin-1, s-farnesyl-l-cysteine methyl ester
Authors:Grant, B.M.M, Enomoto, M, Lee, K.Y, Back, S.I, Gebregiworgis, T, Ishiyama, N, Ikura, M, Marshall, C.
Deposit date:2019-05-01
Release date:2020-04-08
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Calmodulin disrupts plasma membrane localization of farnesylated KRAS4b by sequestering its lipid moiety.
Sci.Signal., 13, 2020
5WI4
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BU of 5wi4 by Molmil
CRYSTAL STRUCTURE OF DYNLT1/TCTEX-1 IN COMPLEX WITH ARHGEF2
Descriptor: Dynein light chain Tctex-type 1,Rho guanine nucleotide exchange factor 2, SULFATE ION
Authors:Balan, M, Ishiyama, N, Marshall, C.B, Ikura, M.
Deposit date:2017-07-18
Release date:2017-11-15
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2 Å)
Cite:MARK3-mediated phosphorylation of ARHGEF2 couples microtubules to the actin cytoskeleton to establish cell polarity.
Sci Signal, 10, 2017
6PW7
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BU of 6pw7 by Molmil
X-ray crystal structure of C. elegans STIM EF-SAM domain
Descriptor: CALCIUM ION, Stromal interaction molecule 1
Authors:Enomoto, M, Nishikawa, T, Back, S.I, Ishiyama, N, Zheng, L, Stathopulos, P.B, Ikura, M.
Deposit date:2019-07-22
Release date:2019-11-13
Last modified:2020-02-12
Method:X-RAY DIFFRACTION (1.89 Å)
Cite:Coordination of a Single Calcium Ion in the EF-hand Maintains the Off State of the Stromal Interaction Molecule Luminal Domain.
J.Mol.Biol., 432, 2020
3HSM
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BU of 3hsm by Molmil
Crystal structure of distal N-terminal beta-trefoil domain of Ryanodine Receptor type 1
Descriptor: Ryanodine receptor 1
Authors:Amador, F.J, Liu, S, Ishiyama, N, Plevin, M.J, Wilson, A, MacLennan, D.H, Ikura, M.
Deposit date:2009-06-10
Release date:2009-07-28
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of type I ryanodine receptor amino-terminal beta-trefoil domain reveals a disease-associated mutation "hot spot" loop
Proc.Natl.Acad.Sci.USA, 106, 2009
6AMB
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BU of 6amb by Molmil
Crystal Structure of the Afadin RA1 domain in complex with HRAS
Descriptor: Afadin, GTPase HRas, MAGNESIUM ION, ...
Authors:Smith, M.J, Ishiyama, N, Ikura, M.
Deposit date:2017-08-09
Release date:2017-11-01
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Evolution of AF6-RAS association and its implications in mixed-lineage leukemia.
Nat Commun, 8, 2017
3JRR
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BU of 3jrr by Molmil
Crystal structure of the ligand binding suppressor domain of type 3 inositol 1,4,5-trisphosphate receptor
Descriptor: Inositol 1,4,5-trisphosphate receptor type 3
Authors:Chan, J, Ishiyama, N, Ikura, M.
Deposit date:2009-09-08
Release date:2010-09-15
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:A 1.9 angstrom crystal structure of the suppressor domain of type 3 inositol 1,4,5-trisphosphate receptor
To be Published
4O2R
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BU of 4o2r by Molmil
Structure of Mus musculus Rheb G63V mutant bound to GDP
Descriptor: GTP-binding protein Rheb, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION
Authors:Mazhab-Jafari, M.T, Marshall, C.B, Ho, J, Ishiyama, N, Stambolic, V, Ikura, M.
Deposit date:2013-12-17
Release date:2014-03-26
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Structure-guided mutation of the conserved G3-box glycine in Rheb generates a constitutively activated regulator of mammalian target of rapamycin (mTOR).
J.Biol.Chem., 289, 2014
4O25
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BU of 4o25 by Molmil
Structure of Wild Type Mus musculus Rheb bound to GTP
Descriptor: GTP-binding protein Rheb, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION
Authors:Mazhab-Jafari, M.T, Marshall, C.B, Ho, J, Ishiyama, N, Stambolic, V, Ikura, M.
Deposit date:2013-12-16
Release date:2014-03-26
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure-guided mutation of the conserved G3-box glycine in Rheb generates a constitutively activated regulator of mammalian target of rapamycin (mTOR).
J.Biol.Chem., 289, 2014
4O2L
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BU of 4o2l by Molmil
Structure of Mus musculus Rheb G63A mutant bound to GTP
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ACETATE ION, GTP-binding protein Rheb, ...
Authors:Mazhab-Jafari, M.T, Marshall, C.B, Ho, J, Ishiyama, N, Stambolic, V, Ikura, M.
Deposit date:2013-12-17
Release date:2014-03-26
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structure-guided mutation of the conserved G3-box glycine in Rheb generates a constitutively activated regulator of mammalian target of rapamycin (mTOR).
J.Biol.Chem., 289, 2014
3UJ4
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BU of 3uj4 by Molmil
Crystal structure of the apo-inositol 1,4,5-trisphosphate receptor
Descriptor: Inositol 1,4,5-trisphosphate receptor type 1, SULFATE ION
Authors:Ikura, M, Seo, M.D, Ishiyama, N, Stathopulos, P.
Deposit date:2011-11-07
Release date:2012-02-15
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural and functional conservation of key domains in InsP3 and ryanodine receptors.
Nature, 483, 2012
3UJ0
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Crystal structure of the inositol 1,4,5-trisphosphate receptor with ligand bound form.
Descriptor: D-MYO-INOSITOL-1,4,5-TRIPHOSPHATE, Inositol 1,4,5-trisphosphate receptor type 1
Authors:Ikura, M, Seo, M.D, Ishiyama, N, Stathopulos, P.
Deposit date:2011-11-07
Release date:2012-02-15
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:Structural and functional conservation of key domains in InsP3 and ryanodine receptors.
Nature, 483, 2012

 

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