1OMY | | CRYSTAL STRUCTURE OF A RECOMBINANT ALPHA-INSECT TOXIN BMKAIT1 FROM THE SCORPION BUTHUS MARTENSII KARSCH | | 分子名称: | Alpha-neurotoxin TX12, CHLORIDE ION, ACETIC ACID | | 著者 | Huang, Y., Huang, Q., Chen, H., Tang, Y., Miyake, H., Kusunoki, M. | | 登録日 | 2003-02-26 | | 公開日 | 2003-09-09 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Crystallization and preliminary crystallographic study of rBmKalphaIT1, a recombinant alpha-insect toxin from the scorpion Buthus martensii Karsch.
Acta Crystallogr.,Sect.D, 59, 2003
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3HTX | | CRYSTAL STRUCTURE OF SMALL RNA METHYLTRANSFERASE HEN1 | | 分子名称: | HEN1, 5'-R(*GP*AP*UP*UP*UP*CP*UP*CP*UP*CP*UP*GP*CP*AP*AP*GP*CP*GP*AP*AP*AP*G)-3', 5'-R(P*UP*UP*CP*GP*CP*UP*UP*GP*CP*AP*GP*AP*GP*AP*GP*AP*AP*AP*UP*CP*AP*C)-3', ... | | 著者 | Huang, Y., Ji, L.-J., Huang, Q.-C., Vassylyev, D.G., Chen, X.-M., Ma, J.-B. | | 登録日 | 2009-06-12 | | 公開日 | 2009-09-29 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | Structural insights into mechanisms of the small RNA methyltransferase HEN1.
Nature, 461, 2009
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1D2G | | CRYSTAL STRUCTURE OF R175K MUTANT GLYCINE N-METHYLTRANSFERASE FROM RAT LIVER | | 分子名称: | GLYCINE N-METHYLTRANSFERASE | | 著者 | Huang, Y., Komoto, J., Takusagawa, F., Konishi, K., Takata, Y. | | 登録日 | 1999-10-08 | | 公開日 | 1999-10-25 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Mechanisms for auto-inhibition and forced product release in glycine N-methyltransferase: crystal structures of wild-type, mutant R175K and S-adenosylhomocysteine-bound R175K enzymes.
J.Mol.Biol., 298, 2000
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1D2H | | CRYSTAL STRUCTURE OF R175K MUTANT GLYCINE N-METHYLTRANSFERASE COMPLEXED WITH S-ADENOSYLHOMOCYSTEINE | | 分子名称: | GLYCINE N-METHYLTRANSFERASE, S-ADENOSYL-L-HOMOCYSTEINE | | 著者 | Huang, Y., Komoto, J., Takusagawa, F., Konishi, K., Takata, Y. | | 登録日 | 1999-10-11 | | 公開日 | 1999-10-25 | | 最終更新日 | 2017-10-04 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Mechanisms for auto-inhibition and forced product release in glycine N-methyltransferase: crystal structures of wild-type, mutant R175K and S-adenosylhomocysteine-bound R175K enzymes.
J.Mol.Biol., 298, 2000
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2GF7 | | DOUBLE TUDOR DOMAIN STRUCTURE | | 分子名称: | Jumonji domain-containing protein 2A, SULFATE ION | | 著者 | Huang, Y., Fang, J., Bedford, M.T., Zhang, Y., Xu, R.M. | | 登録日 | 2006-03-21 | | 公開日 | 2006-05-02 | | 最終更新日 | 2017-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Recognition of histone H3 lysine-4 methylation by the double tudor domain of JMJD2A
Science, 312, 2006
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2GFA | | DOUBLE TUDOR DOMAIN COMPLEX STRUCTURE | | 分子名称: | Jumonji domain-containing protein 2A, peptide | | 著者 | Huang, Y., Fang, J., Bedford, M.T., Zhang, Y., Xu, R.M. | | 登録日 | 2006-03-21 | | 公開日 | 2006-05-02 | | 最終更新日 | 2017-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Recognition of histone H3 lysine-4 methylation by the double tudor domain of JMJD2A
Science, 312, 2006
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1D2C | | METHYLTRANSFERASE | | 分子名称: | PROTEIN (GLYCINE N-METHYLTRANSFERASE) | | 著者 | Huang, Y., Takusagawa, F. | | 登録日 | 1999-09-23 | | 公開日 | 1999-10-06 | | 最終更新日 | 2018-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Mechanisms for auto-inhibition and forced product release in glycine N-methyltransferase: crystal structures of wild-type, mutant R175K and S-adenosylhomocysteine-bound R175K enzymes.
J.Mol.Biol., 298, 2000
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1I4O | | CRYSTAL STRUCTURE OF THE XIAP/CASPASE-7 COMPLEX | | 分子名称: | CASPASE-7, BACULOVIRAL IAP REPEAT-CONTAINING PROTEIN 4 | | 著者 | Huang, Y., Park, Y.C., Rich, R.L., Segal, D., Myszka, D.G., Wu, H. | | 登録日 | 2001-02-22 | | 公開日 | 2001-03-21 | | 最終更新日 | 2017-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structural basis of caspase inhibition by XIAP: differential roles of the linker versus the BIR domain.
Cell(Cambridge,Mass.), 104, 2001
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1PW4 | | CRYSTAL STRUCTURE OF THE GLYCEROL-3-PHOSPHATE TRANSPORTER FROM E.COLI | | 分子名称: | Glycerol-3-phosphate transporter | | 著者 | Huang, Y., Lemieux, M.J., Song, J., Auer, M., Wang, D.N. | | 登録日 | 2003-06-30 | | 公開日 | 2003-08-05 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | | 主引用文献 | Structure and Mechanism of the Glycerol-3-Phosphate Transporter from Escherichia Coli
Science, 301, 2003
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2FMM | | CRYSTAL STRUCTURE OF EMSY-HP1 COMPLEX | | 分子名称: | Protein EMSY, Chromobox protein homolog 1, SULFATE ION | | 著者 | Huang, Y. | | 登録日 | 2006-01-09 | | 公開日 | 2006-05-23 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Crystal structure of the HP1-EMSY complex reveals an unusual mode of HP1 binding.
Structure, 14, 2006
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2IJG | |
3FIP | |
3MJ0 | |
5WQA | | CRYSTAL STRUCTURE OF PDE4D CATALYTIC DOMAIN COMPLEXED WITH SELAGINPULVILINS K | | 分子名称: | cAMP-specific 3',5'-cyclic phosphodiesterase 4D, 1-[2-(4-hydroxyphenyl)ethynyl]-9,9-bis(4-methoxyphenyl)-7-oxidanyl-fluorene-2-carbaldehyde, ZINC ION, ... | | 著者 | Huang, Y., Zhang, T., Zheng, X., Yin, S., Luo, H.B. | | 登録日 | 2016-11-24 | | 公開日 | 2017-02-22 | | 最終更新日 | 2017-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | The discovery, complex crystal structure, and recognition mechanism of a novel natural PDE4 inhibitor from Selaginella pulvinata
Biochem. Pharmacol., 130, 2017
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6A6L | |
3X2R | | STRUCTURE OF THE NONAMERIC BACTERIAL AMYLOID SECRETION CHANNEL CSGG | | 分子名称: | CsgG | | 著者 | Huang, Y., Cao, B., Zhao, Y., Kou, Y., Ni, D., Zhang, X.C. | | 登録日 | 2014-12-29 | | 公開日 | 2015-01-21 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Structure of the nonameric bacterial amyloid secretion channel
Proc.Natl.Acad.Sci.USA, 111, 2014
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4Q79 | | STRUCTURE OF A HG-DERIVATIVE CSGG | | 分子名称: | CsgG, MERCURY (II) ION | | 著者 | Huang, Y., Zhang, C.X., Cao, B., Zhao, Y., Kou, Y., Ni, D. | | 登録日 | 2014-04-24 | | 公開日 | 2014-12-17 | | 最終更新日 | 2015-04-08 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | Structure of the nonameric bacterial amyloid secretion channel
Proc.Natl.Acad.Sci.USA, 111, 2014
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1K0U | | INHIBITION OF S-ADENOSYLHOMOCYSTEINE HYDROLASE BY "ACYCLIC SUGAR" ADENOSINE ANALOGUE D-ERITADENINE | | 分子名称: | S-ADENOSYL-L-HOMOCYSTEINE HYDROLASE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, D-ERITADENINE | | 著者 | Takusagawa, F., Huang, Y., Komoto, J., Takata, Y., Gomi, T., Ogawa, H., Fujioka, M., Powell, D. | | 登録日 | 2001-09-20 | | 公開日 | 2001-10-17 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Inhibition of S-adenosylhomocysteine hydrolase by acyclic sugar adenosine analogue D-eritadenine. Crystal structure of S-adenosylhomocysteine hydrolase complexed with D-eritadenine.
J.Biol.Chem., 277, 2002
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4Q35 | | STRUCTURE OF A MEMBRANE PROTEIN | | 分子名称: | LPS-assembly protein LptD, LPS-assembly lipoprotein LptE, (HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE, ... | | 著者 | Huang, Y., Qiao, S., Luo, Q., Zhao, Y. | | 登録日 | 2014-04-11 | | 公開日 | 2014-06-25 | | 最終更新日 | 2014-07-09 | | 実験手法 | X-RAY DIFFRACTION (2.393 Å) | | 主引用文献 | Structural basis for lipopolysaccharide insertion in the bacterial outer membrane
Nature, 511, 2014
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5AYW | | STRUCTURE OF A MEMBRANE COMPLEX | | 分子名称: | Outer membrane protein assembly factor BamA, Outer membrane protein assembly factor BamB, Outer membrane protein assembly factor BamC, ... | | 著者 | Huang, Y., Han, L., Zheng, J. | | 登録日 | 2015-09-14 | | 公開日 | 2016-02-24 | | 最終更新日 | 2017-09-27 | | 実験手法 | X-RAY DIFFRACTION (3.555 Å) | | 主引用文献 | Structure of the BAM complex and its implications for biogenesis of outer-membrane proteins
Nat.Struct.Mol.Biol., 23, 2016
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5IN1 | |
5Y82 | |
5Y83 | |
6AKW | | CRYSTAL STRUCTURE OF RNA DIOXYGENASE BOUND WITH AN INHIBITOR | | 分子名称: | Alpha-ketoglutarate-dependent dioxygenase FTO, 2-OXOGLUTARIC ACID, 2-[[2,6-bis(chloranyl)-4-(3,5-dimethyl-1,2-oxazol-4-yl)phenyl]amino]benzoic acid | | 著者 | Yang, C.-G., Huang, Y., Gan, J. | | 登録日 | 2018-09-04 | | 公開日 | 2019-05-29 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Small-Molecule Targeting of Oncogenic FTO Demethylase in Acute Myeloid Leukemia.
Cancer Cell, 35, 2019
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6JKK | | CRYSTAL STRUCTURE OF BUBR1 KINASE DOMAIN | | 分子名称: | Mitotic checkpoint control protein kinase BUB1, GLYCEROL, DI(HYDROXYETHYL)ETHER | | 著者 | Lin, L., Ye, S., Huang, Y., Liu, X., Zhang, R., Yao, X. | | 登録日 | 2019-03-01 | | 公開日 | 2019-06-26 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | BubR1 phosphorylates CENP-E as a switch enabling the transition from lateral association to end-on capture of spindle microtubules.
Cell Res., 2019
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