8SR8

Cryo-EM structure of TRPM2 chanzyme in the presence of EDTA (apo state)

Summary for 8SR8

• Entry DOI: 10.2210/pdb8sr8/pdb
• EMDB information: 40722 40895
• Descriptor: TRPM2 chanzyme, CHOLESTEROL (2 entities in total)
• Functional Keywords: trpm2 chanzyme, channel-enzyme, transport protein
• Biological source: Salpingoeca rosetta
• Total number of polymer chains: 4
• Total formula weight: 677649.78

Authors

Huang, Y.,Kumar, S.,Lu, W.,Du, J. (deposition date: 2023-05-05, release date: 2024-05-08)

• Primary citation: Huang, Y.,Kumar, S.,Lu, W.,Du, J.; Coupling enzymatic activity and gating in an ancient TRPM chanzyme and its molecular evolution; To Be Published,

Experimental method

ELECTRON MICROSCOPY (2.77 Å)