1D2H
CRYSTAL STRUCTURE OF R175K MUTANT GLYCINE N-METHYLTRANSFERASE COMPLEXED WITH S-ADENOSYLHOMOCYSTEINE
Summary for 1D2H
| Entry DOI | 10.2210/pdb1d2h/pdb |
| Related | 1D2C 1D2G 1XVA |
| Descriptor | GLYCINE N-METHYLTRANSFERASE, S-ADENOSYL-L-HOMOCYSTEINE (3 entities in total) |
| Functional Keywords | methyltransferase, transferase |
| Biological source | Rattus norvegicus (Norway rat) |
| Cellular location | Cytoplasm: P13255 |
| Total number of polymer chains | 4 |
| Total formula weight | 131268.92 |
| Authors | Huang, Y.,Komoto, J.,Takusagawa, F.,Konishi, K.,Takata, Y. (deposition date: 1999-10-11, release date: 1999-10-25, Last modification date: 2024-02-07) |
| Primary citation | Huang, Y.,Komoto, J.,Konishi, K.,Takata, Y.,Ogawa, H.,Gomi, T.,Fujioka, M.,Takusagawa, F. Mechanisms for auto-inhibition and forced product release in glycine N-methyltransferase: crystal structures of wild-type, mutant R175K and S-adenosylhomocysteine-bound R175K enzymes. J.Mol.Biol., 298:149-162, 2000 Cited by PubMed: 10756111DOI: 10.1006/jmbi.2000.3637 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (3 Å) |
Structure validation
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