Author results

3N3Z
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CRYSTAL STRUCTURE OF PDE9A (E406A) MUTANT IN COMPLEX WITH IBMX
Descriptor:High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A, 3-ISOBUTYL-1-METHYLXANTHINE, ZINC ION, ...
Authors:Hou, J., Luo, H.-B., Chen, Y., Xu, J., Zhao, R., Zou, L.
Deposit date:2010-05-21
Release date:2011-04-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Crystal structure of PDE9A (E406A) mutation in complex with IBMX
To be Published
3QI3
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CRYSTAL STRUCTURE OF PDE9A(Q453E) IN COMPLEX WITH INHIBITOR BAY73-6691
Descriptor:High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A, 1-(2-chlorophenyl)-6-[(2R)-3,3,3-trifluoro-2-methylpropyl]-1,7-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one, ZINC ION, ...
Authors:Hou, J., Xu, J., Liu, M., Zhao, R., Lou, H., Ke, H.
Deposit date:2011-01-26
Release date:2011-04-27
Last modified:2014-02-19
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural asymmetry of phosphodiesterase-9, potential protonation of a glutamic Acid, and role of the invariant glutamine.
Plos One, 6, 2011
3QI4
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CRYSTAL STRUCTURE OF PDE9A(Q453E) IN COMPLEX WITH IBMX
Descriptor:High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A, 3-ISOBUTYL-1-METHYLXANTHINE, ZINC ION, ...
Authors:Hou, J., Xu, J., Liu, M., Zhao, R., Lou, H., Ke, H.
Deposit date:2011-01-26
Release date:2011-04-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural asymmetry of phosphodiesterase-9, potential protonation of a glutamic Acid, and role of the invariant glutamine.
Plos One, 6, 2011
3ICC
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CRYSTAL STRUCTURE OF A PUTATIVE 3-OXOACYL-(ACYL CARRIER PROTEIN) REDUCTASE FROM BACILLUS ANTHRACIS AT 1.87 A RESOLUTION
Descriptor:Putative 3-oxoacyl-(acyl carrier protein) reductase, CHLORIDE ION, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
Authors:Hou, J., Chruszcz, M., Zheng, H., Cymborowski, M., Luo, H.-B., Skarina, T., Gordon, S., Savchenko, A., Edwards, A.M., Anderson, W., Minor, W., Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2009-07-17
Release date:2009-07-28
Last modified:2012-12-26
Method:X-RAY DIFFRACTION (1.87 Å)
Cite:Structure of a short-chain dehydrogenase/reductase from Bacillus anthracis.
Acta Crystallogr.,Sect.F, 68, 2012
3K3S
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CRYSTAL STRUCTURE OF ALTRONATE HYDROLASE (FRAGMENT 1-84) FROM SHIGELLA FLEXNERI.
Descriptor:Altronate hydrolase, MALONIC ACID, ACETATE ION, ...
Authors:Hou, J., Chruszcz, M., Xu, X., Le, B., Zimmerman, M.D., Savchenko, A., Edwards, A.M., Joachimiak, A., Minor, W., Midwest Center for Structural Genomics (MCSG)
Deposit date:2009-10-04
Release date:2009-10-27
Last modified:2015-04-29
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Crystal structure of altronate hydrolase (fragment 1-84) from Shigella Flexneri.
To be Published
3OP4
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CRYSTAL STRUCTURE OF PUTATIVE 3-KETOACYL-(ACYL-CARRIER-PROTEIN) REDUCTASE FROM VIBRIO CHOLERAE O1 BIOVAR ELTOR STR. N16961 IN COMPLEX WITH NADP+
Descriptor:3-oxoacyl-[acyl-carrier protein] reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ACETATE ION
Authors:Hou, J., Chruszcz, M., Onopriyenko, O., Grimshaw, S., Porebski, P., Zheng, H., Savchenko, A., Anderson, W., Minor, W., Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2010-08-31
Release date:2010-09-22
Last modified:2016-03-23
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Dissecting the Structural Elements for the Activation of beta-Ketoacyl-(Acyl Carrier Protein) Reductase from Vibrio cholerae.
J.Bacteriol., 198, 2015
3RRO
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CRYSTAL STRUCTURE OF 3-KETOACYL-(ACYL-CARRIER-PROTEIN) REDUCTASE (FABG) FROM VIBRIO CHOLERAE
Descriptor:3-ketoacyl-(acyl-carrier-protein) reductase, SULFATE ION, TRIETHYLENE GLYCOL, ...
Authors:Hou, J., Chruszcz, M., Cooper, D.R., Grabowski, M., Zheng, H., Osinski, T., Shumilin, I., Anderson, W., Minor, W., Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2011-04-29
Release date:2011-05-18
Last modified:2016-03-23
Method:X-RAY DIFFRACTION (2 Å)
Cite:Dissecting the Structural Elements for the Activation of beta-Ketoacyl-(Acyl Carrier Protein) Reductase from Vibrio cholerae.
J.Bacteriol., 198, 2015
3RSH
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STRUCTURE OF 3-KETOACYL-(ACYL-CARRIER-PROTEIN)REDUCTASE (FABG) FROM VIBRIO CHOLERAE O1 COMPLEXED WITH NADP+ (SPACE GROUP P62)
Descriptor:3-oxoacyl-[acyl-carrier protein] reductase, SULFATE ION, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
Authors:Hou, J., Chruszcz, M., Cooper, D.R., Grabowski, M., Zheng, H., Osinski, T., Shumilin, I., Anderson, W., Minor, W., Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2011-05-02
Release date:2011-05-11
Last modified:2016-03-23
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Dissecting the Structural Elements for the Activation of beta-Ketoacyl-(Acyl Carrier Protein) Reductase from Vibrio cholerae.
J.Bacteriol., 198, 2015
3T5P
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CRYSTAL STRUCTURE OF A PUTATIVE DIACYLGLYCEROL KINASE FROM BACILLUS ANTHRACIS STR. STERNE
Descriptor:BmrU protein, MAGNESIUM ION
Authors:Hou, J., Zheng, H., Chruszcz, M., Cooper, D.R., Onopriyenko, O., Grimshaw, S., Savchenko, A., Anderson, W.F., Minor, W., Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2011-07-27
Release date:2011-09-07
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of a putative diacylglycerol kinase from Bacillus anthracis str. Sterne
To be Published
3TZC
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CRYSTAL STRUCTURE OF 3-KETOACYL-(ACYL-CARRIER-PROTEIN) REDUCTASE (FABG)(Y155F) FROM VIBRIO CHOLERAE
Descriptor:3-oxoacyl-[acyl-carrier protein] reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, SULFATE ION
Authors:Hou, J., Chruszcz, M., Zheng, H., Grabowski, M., Domagalski, M., Anderson, W.F., Minor, W., Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2011-09-27
Release date:2011-10-19
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Dissecting the Structural Elements for the Activation of beta-Ketoacyl-(Acyl Carrier Protein) Reductase from Vibrio cholerae.
J.Bacteriol., 198, 2015
3TZK
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CRYSTAL STRUCTURE OF 3-KETOACYL-(ACYL-CARRIER-PROTEIN) REDUCTASE (FABG)(G92A) FROM VIBRIO CHOLERAE
Descriptor:3-oxoacyl-[acyl-carrier protein] reductase, SULFATE ION, UNKNOWN ATOM OR ION
Authors:Hou, J., Chruszcz, M., Zheng, H., Grabowski, M., Domagalski, M., Anderson, W.F., Minor, W., Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2011-09-27
Release date:2011-10-19
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Dissecting the Structural Elements for the Activation of beta-Ketoacyl-(Acyl Carrier Protein) Reductase from Vibrio cholerae.
J.Bacteriol., 198, 2015
3U09
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CRYSTAL STRUCTURE OF 3-KETOACYL-(ACYL-CARRIER-PROTEIN) REDUCTASE (FABG)(G92D) FROM VIBRIO CHOLERAE
Descriptor:3-oxoacyl-[acyl-carrier-protein] reductase FabG, SULFATE ION, UNKNOWN ATOM OR ION
Authors:Hou, J., Chruszcz, M., Zheng, H., Grabowski, M., Fratczak, Z., Anderson, W.F., Minor, W., Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2011-09-28
Release date:2011-10-19
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Dissecting the Structural Elements for the Activation of beta-Ketoacyl-(Acyl Carrier Protein) Reductase from Vibrio cholerae.
J.Bacteriol., 198, 2015
4GAF
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CRYSTAL STRUCTURE OF EBI-005, A CHIMERA OF HUMAN IL-1BETA AND IL-1RA, BOUND TO HUMAN INTERLEUKIN-1 RECEPTOR TYPE 1
Descriptor:EBI-005, Interleukin-1 receptor type 1, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Hou, J., Townson, S.A., Kovalchin, J.T., Masci, A., Kiner, O., Shu, Y., King, B., Thomas, C., Garcia, K.C., Furfine, E.S., Barnes, T.M.
Deposit date:2012-07-25
Release date:2013-02-20
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Design of a superior cytokine antagonist for topical ophthalmic use.
Proc.Natl.Acad.Sci.USA, 110, 2013
4GAI
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CRYSTAL STRUCTURE OF EBI-005, A CHIMERA OF HUMAN IL-1BETA AND IL-1RA
Descriptor:EBI-005
Authors:Hou, J., Townson, S.A., Kovalchin, J.T., Masci, A., Kiner, O., Shu, Y., King, B., Thomas, C., Garcia, K.C., Furfine, E.S., Barnes, T.M.
Deposit date:2012-07-25
Release date:2013-02-20
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (1.49 Å)
Cite:Design of a superior cytokine antagonist for topical ophthalmic use.
Proc.Natl.Acad.Sci.USA, 110, 2013
4I08
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CRYSTAL STRUCTURE OF BETA-KETOACYL-ACYL CARRIER PROTEIN REDUCTASE (FABG) FROM VIBRIO CHOLERAE IN COMPLEX WITH NADPH
Descriptor:3-oxoacyl-[acyl-carrier-protein] reductase FabG, SULFATE ION, 1,2-ETHANEDIOL, ...
Authors:Hou, J., Chruszcz, M., Zheng, H., Osinski, T., Anderson, W.F., Minor, W., Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2012-11-16
Release date:2012-12-12
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.063 Å)
Cite:Dissecting the Structural Elements for the Activation of beta-Ketoacyl-(Acyl Carrier Protein) Reductase from Vibrio cholerae.
J.Bacteriol., 198, 2015
4IIN
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CRYSTAL STRUCTURE OF A PUTATIVE 3-OXOACYL-[ACYL-CARRIER PROTEIN]REDUCTASE FROM HELICOBACTER PYLORI 26695 COMPLEXED WITH NAD+
Descriptor:3-ketoacyl-acyl carrier protein reductase (FabG), NICOTINAMIDE-ADENINE-DINUCLEOTIDE, POTASSIUM ION, ...
Authors:Hou, J., Osinski, T., Zheng, H., Shumilin, I., Shabalin, I., Shatsman, S., Anderson, W.F., Minor, W., Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2012-12-20
Release date:2013-01-09
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structure of a putative 3-oxoacyl-[acyl-carrier protein]reductase from Helicobacter pylori 26695 complexed with NAD+
To be Published
4IIU
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CRYSTAL STRUCTURE OF A PUTATIVE 3-OXOACYL-[ACYL-CARRIER PROTEIN]REDUCTASE FROM ESCHERICHIA COLI STRAIN CFT073 COMPLEXED WITH NADP+ AT 2.1 A RESOLUTION
Descriptor:3-oxoacyl-[acyl-carrier protein] reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Hou, J., Osinski, T., Zheng, H., Shumilin, I., Shabalin, I., Shatsman, S., Anderson, W.F., Minor, W., Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2012-12-20
Release date:2013-01-09
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure of a putative 3-oxoacyl-[acyl-carrier protein]reductase from Escherichia coli strain CFT073 complexed with NADP+ at 2.1 A resolution
To be Published
4IIV
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CRYSTAL STRUCTURE OF A PUTATIVE 3-OXOACYL-[ACYL-CARRIER PROTEIN]REDUCTASE FROM ESCHERICHIA COLI STRAIN CFT073 COMPLEXED WITH NADP+ AT 2.5 A RESOLUTION
Descriptor:3-oxoacyl-[acyl-carrier protein] reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Hou, J., Osinski, T., Zheng, H., Shumilin, I., Shabalin, I., Shatsman, S., Anderson, W.F., Minor, W., Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2012-12-20
Release date:2013-01-09
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of a putative 3-oxoacyl-[acyl-carrier protein]reductase from Escherichia coli strain CFT073 complexed with NADP+ at 2.5 A resolution
To be Published
4IJK
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CRYSTAL STRUCTURE OF A PUTATIVE 3-OXOACYL-[ACYL-CARRIER PROTEIN]REDUCTASE FROM HELICOBACTER PYLORI 26695
Descriptor:3-ketoacyl-acyl carrier protein reductase (FabG), SODIUM ION
Authors:Hou, J., Osinski, T., Zheng, H., Shumilin, I., Shabalin, I.G., Shatsman, S., Anderson, W.F., Minor, W., Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2012-12-21
Release date:2013-01-09
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.54 Å)
Cite:Crystal structure of a putative 3-oxoacyl-[acyl-carrier protein]reductase from Helicobacter pylori 26695
To be Published
4JRM
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CRYSTAL STRUCTURE OF BETA-KETOACYL-ACP SYNTHASE II (FABF) FROM VIBRIO CHOLERAE (SPACE GROUP P212121) AT 1.75 ANGSTROM
Descriptor:3-oxoacyl-[acyl-carrier-protein] synthase 2, ACETATE ION, GLYCEROL
Authors:Hou, J., Chruszcz, M., Shabalin, I.G., Zheng, H., Cooper, D.R., Anderson, W.F., Minor, W., Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2013-03-21
Release date:2013-04-03
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Crystal structure of beta-ketoacyl-ACP synthase II (FabF) from Vibrio cholerae (space group P43) at 2.2 Angstrom
To be Published
4JRO
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CRYSTAL STRUCTURE OF 3-OXOACYL-[ACYL-CARRIER PROTEIN]REDUCTASE (FABG)FROM LISTERIA MONOCYTOGENES IN COMPLEX WITH NADP+
Descriptor:FabG protein, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Hou, J., Zheng, H., Cooper, D.R., Osinski, T., Shatsman, S., Anderson, W.F., Minor, W., Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2013-03-21
Release date:2013-04-03
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (1.92 Å)
Cite:Crystal structure of 3-oxoacyl-[acyl-carrier protein]reductase (FabG)from Listeria monocytogenes in complex with NADP+
To be Published
4NHD
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CRYSTAL STRUCTURE OF BETA-KETOACYL-ACP SYNTHASE III (FABH) FROM VIBRIO CHOLERAE IN COMPLEX WITH COENZYME A
Descriptor:3-oxoacyl-[acyl-carrier-protein] synthase 3 protein 1, COENZYME A, CALCIUM ION, ...
Authors:Hou, J., Zheng, H., Langner, K., Anderson, W.F., Minor, W., Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2013-11-04
Release date:2013-12-25
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (1.78 Å)
Cite:Crystal structure of beta-ketoacyl-ACP synthase III (FabH) from Vibrio Cholerae in complex with Coenzyme A
To be Published
4WJZ
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CRYSTAL STRUCTURE OF BETA-KETOACYL-ACYL CARRIER PROTEIN REDUCTASE (FABG)(G141A) FROM VIBRIO CHOLERAE
Descriptor:3-oxoacyl-[acyl-carrier-protein] reductase FabG, PHOSPHATE ION
Authors:Hou, J., Zheng, H., Anderson, W.F., Minor, W., Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2014-10-01
Release date:2014-11-12
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Dissecting the Structural Elements for the Activation of beta-Ketoacyl-(Acyl Carrier Protein) Reductase from Vibrio cholerae.
J.Bacteriol., 198, 2015
4WK6
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CRYSTAL STRUCTURE OF 3-KETOACYL-(ACYL-CARRIER-PROTEIN) REDUCTASE (FABG) (G141A) FROM VIBRIO CHOLERAE IN COMPLEX WITH NADPH
Descriptor:3-oxoacyl-[acyl-carrier protein] reductase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, PENTAETHYLENE GLYCOL
Authors:Hou, J., Zheng, H., Anderson, W.F., Minor, W., Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2014-10-01
Release date:2014-11-12
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (2.21 Å)
Cite:Dissecting the Structural Elements for the Activation of beta-Ketoacyl-(Acyl Carrier Protein) Reductase from Vibrio cholerae.
J.Bacteriol., 198, 2015
4WRR
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A PUTATIVE DIACYLGLYCEROL KINASE FROM BACILLUS ANTHRACIS STR. STERNE
Descriptor:putative diacylglycerol kinase, MAGNESIUM ION
Authors:Hou, J., Zheng, H., Cooper, D.R., Zimmerman, M.D., Anderson, W.F., Minor, W., Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2014-10-24
Release date:2014-11-05
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (2.16 Å)
Cite:Crystal structure of a putative diacylglycerol kinase from Bacillus anthracis str. Sterne
to be published
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