Beta-ketoacyl-ACP synthase III -2 (FabH2) (C113A) from Vibrio Cholerae soaked with octanoyl-CoA: conformational changes without clearly bound substrate

Summary for 4X9O

Related4WZU 4X0O 4X9K
Descriptor3-oxoacyl-[acyl-carrier-protein] synthase 3 protein 2 (2 entities in total)
Functional Keywordsstructural genomics, center for structural genomics of infectious diseases, csgid, fabh, beta-ketoacyl-acyl carrier protein synthase iii, transferase
Biological sourceVibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)
Total number of polymer chains2
Total molecular weight78072.23
Hou, J.,Cooper, D.R.,Shabalin, I.G.,Grabowski, M.,Shumilin, I.,Anderson, W.F.,Minor, W.,Center for Structural Genomics of Infectious Diseases (CSGID) (deposition date: 2014-12-11, release date: 2015-03-11, Last modification date: 2019-11-27)
Primary citation
Hou, J.,Zheng, H.,Cooper, D.R.,Chruszcz, M.,Chordia, M.D.,Grabowski, M.,Minor, W.,Center for Structural Genomics of Infectious Diseases (CSGID)
Structural and enzymatic studies of beta-ketoacyl-(acyl carrier protein) synthase III (FabH) from Vibrio cholerae
to be published,
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.23610 1.2% 6.7%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload
PDB entries from 2020-10-14