Beta-ketoacyl-ACP synthase III -2 (FabH2) (C113A) from Vibrio Cholerae soaked with octanoyl-CoA: conformational changes without clearly bound substrate

Summary for 4X9O

Related4WZU 4X0O 4X9K
Descriptor3-oxoacyl-[acyl-carrier-protein] synthase 3 protein 2 (2 entities in total)
Functional Keywordsstructural genomics, center for structural genomics of infectious diseases, csgid, fabh, beta-ketoacyl-acyl carrier protein synthase iii, transferase
Biological sourceVibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)
Cellular locationCytoplasm  Q9KLJ3
Total number of polymer chains2
Total molecular weight78072.23
Hou, J.,Cooper, D.R.,Shabalin, I.G.,Grabowski, M.,Shumilin, I.,Anderson, W.F.,Minor, W.,Center for Structural Genomics of Infectious Diseases (CSGID) (deposition date: 2014-12-11, release date: 2015-03-11, Last modification date: 2017-09-20)
Primary citation
Hou, J.,Zheng, H.,Cooper, D.R.,Chruszcz, M.,Chordia, M.D.,Grabowski, M.,Minor, W.,Center for Structural Genomics of Infectious Diseases (CSGID)
Structural and enzymatic studies of beta-ketoacyl-(acyl carrier protein) synthase III (FabH) from Vibrio cholerae
to be published,
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.236101.2%6.7%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution