3QI4
Crystal structure of PDE9A(Q453E) in complex with IBMX
Summary for 3QI4
Entry DOI | 10.2210/pdb3qi4/pdb |
Related | 3QI3 |
Descriptor | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A, 3-ISOBUTYL-1-METHYLXANTHINE, ZINC ION, ... (5 entities in total) |
Functional Keywords | pde, hydrolase |
Biological source | Homo sapiens (human) |
Cellular location | Isoform PDE9A1: Cell projection, ruffle membrane. Isoform PDE9A2: Cell projection, ruffle membrane. Isoform PDE9A3: Cytoplasm. Isoform PDE9A17: Cytoplasm: O76083 |
Total number of polymer chains | 2 |
Total formula weight | 124204.04 |
Authors | |
Primary citation | Hou, J.,Xu, J.,Liu, M.,Zhao, R.,Luo, H.B.,Ke, H. Structural asymmetry of phosphodiesterase-9, potential protonation of a glutamic Acid, and role of the invariant glutamine. Plos One, 6:e18092-e18092, 2011 Cited by PubMed: 21483814DOI: 10.1371/journal.pone.0018092 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
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