4I08

Crystal structure of beta-ketoacyl-acyl carrier protein reductase (FabG) from Vibrio cholerae in complex with NADPH

Summary for 4I08

• Entry DOI: 10.2210/pdb4i08/pdb
• Descriptor: 3-oxoacyl-[acyl-carrier-protein] reductase FabG, SULFATE ION, 1,2-ETHANEDIOL, ... (5 entities in total)
• Functional Keywords: structural genomics, center for structural genomics of infectious diseases, csgid, vibrio cholerae, fabg, rossmann fold, beta-ketoacyl-acyl carrier protein reductase, short chain dehydrogenase, nadp(h), oxidoreductase
• Biological source: Vibrio cholerae O1
• Total number of polymer chains: 2
• Total formula weight: 55291.83

Authors

Hou, J.,Chruszcz, M.,Zheng, H.,Osinski, T.,Anderson, W.F.,Minor, W.,Center for Structural Genomics of Infectious Diseases (CSGID) (deposition date: 2012-11-16, release date: 2012-12-12, Last modification date: 2023-09-20)

• Primary citation: Hou, J.,Zheng, H.,Chruszcz, M.,Zimmerman, M.D.,Shumilin, I.A.,Osinski, T.,Demas, M.,Grimshaw, S.,Minor, W.; Dissecting the Structural Elements for the Activation of beta-Ketoacyl-(Acyl Carrier Protein) Reductase from Vibrio cholerae.; J.Bacteriol., 198:463-476, 2015; PubMed: 26553852; DOI: 10.1128/JB.00360-15

Experimental method

X-RAY DIFFRACTION (2.063 Å)